• 原料直供
• 试剂商城
• 直接询价

分类

• {SNA} Alcohols, Building Blocks, C11 to C30+, Chemical Synthesis, Organic Building Blocks, Oxygen Compounds
• {SA} Alcohols, Building Blocks, C11 to C30+, Chemical Synthesis, Organic Building Blocks, Oxygen Compounds
• Pharmaceuticals
• Intermediates & Fine Chemicals
• {uni_hamburg} no charge; carbocycle; aromatic; 6RingOnly; 6ring; alcohol; 1fragment
• Aromatics
• {SNA} Analytical Standards, EP Standards, EP Standards C - D, Pharmacopeia Metrological Institutes Standards, 分析/色谱
• {SNA} Analytical Standards, Analytical/Chromatography, Chromatography, EP Standards, EP Standards C - D, Pharmaceutical Standards, Pharmacopeia Standards

产品应用

• 主要用于有机合成，医药工业作为苯甲托品，苯海拉明的中间体。

相关文献及参考

• Short: III/35D2
• Short: II/27B
• Merck: 14,1090 Beilstein:6,678
• The protection of OH groups as benzhydryl ethers can be catalyzed by sulfuric acid: Org. Synth. Coll., 4, 72 (1963); Angew. Chem. Int. Ed., 15, 281 (1976). See also Benzhydryl­ bromide, L02211. Thiols, e.g. in cysteine residues in peptide synthesis, can be protected as thioethers in the presence of TFA or HBr/AcOH: J. Chem. Soc. (C), 2683 (1970). The group can be cleaved by TFA in the presence of a cation scavenger, e.g. phenol or anisole (same ref.), or by Na in liquid NH3: J. Am. Chem. Soc., 84, 3887 (1962). See Appendix 6.
• Kumar, C., et al.: Eur. J. Med. Chem., 44, 1223 (2009),
• Carboxyl groups can be protected by esterification in benzene with tosic acid catalyst. Deprotection can be effected with the same catalyst by refluxing in toluene, which undergoes electrophilic alkylation: Tetrahedron Lett., 37, 1965 (1996).
• Merck: 14,1090

安全信息

TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - guinea pig
DOSE/DURATION           : 2 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JPETAB Journal of Pharmacology and Experimental Therapeutics.  (Williams &
   Wilkins Co., 428 E. Preston St., Baltimore, MD 21202)  V.1-    1909/10-
   Volume(issue)/page/year: 24,405,1925

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Administration onto the skin
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : >5 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   FCTXAV Food and Cosmetics Toxicology.  (London, UK)  V.1-19, 1963-81.  For
   publisher information, see FCTOD7.  Volume(issue)/page/year: 17,713,1979

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 5 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   FCTXAV Food and Cosmetics Toxicology.  (London, UK)  V.1-19, 1963-81.  For
   publisher information, see FCTOD7.  Volume(issue)/page/year: 17,713,1979

其他信息

• TCI Shanghai:二苯甲醇 Benzhydrol,>;99.0%(GC)(91-01-0)
• 二苯甲醇价格(试剂级):更新日期 产品编号 产品名称 包装 价格 2011/08/23 AB485602 二苯基甲醇 100g 433元 2011/08/23 30075481 二苯基甲醇 100g 400元 2011/04/16 D0898 二苯甲醇 Benzhydrol 500G 869元
• Alfa Aesar:二苯基甲醇,99% Benzhydrol, 99%(91-01-0)
• 易溶于乙醇、醚、氯仿和二硫化碳。水中溶解度:0.5 g/L (20°C)
• 用途二:主要用于有机合成，医药工业作为苯甲托品，苯海拉明的中间体。
• 图谱信息:二苯甲醇(91-01-0)红外图谱(IR1) 二苯甲醇(91-01-0)质谱(MS) 二苯甲醇(91-01-0)红外图谱(IR2) 二苯甲醇(91-01-0)Raman光谱 二苯甲醇(91-01-0)核磁图( 13 CNMR) 二苯甲醇(91-01-0)核磁图( 1 HNMR)
• MSDS 信息:Diphenylcarbinol(91-01-0).msds
• MOL 文件:91-01-0.mol
• Hazard Note:Irritant
• 海关编码:29062900
• 用途一:用作医药中间体，用于合成苯甲托品、苯海拉明等药物
• Acros Organics:二苯基甲醇 Benzhydrol, 99%(91-01-0)
• Sigma Aldrich:91-01-0(sigmaaldrich)
• 上游原料:锌粉 --> 二苯甲酮
• 下游产品:酸性蓝 74 --> 奈福泮 --> 二苯甲基哌嗪 --> 氯代(邻氯苯基)二苯基甲烷 --> (2-氯苯基)二苯基甲醇 --> C.I.酸性绿16