Hematoporphyrin 血卟啉
CAS 14459-29-1 MFCD00005077
化学结构图
SMILES: CC1=C(C(C)O)C2=CC3=NC(=CC4NC(C=C5N=C(C=C1N2)C(C)=C5CCC(O)=O)=C(CCC(O)=O)C=4C)C(C(C)O)=C3C
化学属性
| Mol. Formula | C34H38N4O6 |
|---|---|
| Mol. Weight | 598.69 |
别名和识别编码
| Chemical Name | Hematoporphyrin |
|---|---|
| Synonym | Hematoporphyrin Photodyn 8,13-双(1-羟乙基)-3,7,12,17-四甲基-21H,23H-卟吩-2,18-二丙酸 血卟啉 HP 1,3,5,8-Tetramethyl-2,4-bis(alpha-hydroxyethyl)prophine-6,7-dipropionic |
| MDL Number | MFCD00005077 |
| PubChem Substance ID | 24895696 |
| Beilstein Registry Number | 78957 |
| CAS Number | 14459-29-1 |
| EC Number | 238-450-7 |
| Chemical Name Translation | 血卟啉 |
| Wiswesser Line Notation | T D5 I5 N5-16-5 A D- I- N- AM D-N I-M N-NJ EYQ F JK2VQ O2VQ TYQ U |
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分类
- Biochemicals and Reagents, Catalysis and Inorganic Chemistry, Chemical Synthesis, Hematoporphyrin, Plasma & Blood Proteins, Plasma, Blood, and Related Proteins and Reagents, Porphyrins, Proteins and Derivatives
- {SNA} Biochemicals and Reagents, Catalysis and Inorganic Chemistry, Chemical Synthesis, Hematoporphyrin, Plasma & Blood Proteins, Plasma, Blood, and Related Proteins and Reagents, Porphyrins, Proteins and Derivatives
相关文献及参考
- [2]. Yuan SX, et, al. Underlying mechanism of the photodynamic activity of hematoporphyrin‑induced apoptosis in U87 glioma cells. Int J Mol Med. 2018 Apr;41(4):2288-2296.
- [3]. Tomio L, et, al. Effect of hematoporphyrin and red light on AH-130 solid tumors in rats. Acta Radiol Oncol. 1983;22(1):49-53.
- Beil. 26 ,IV,3157
- FT-IR 1 (2), 575:C / FT-IR 2 (3), 3425:C / RegBook 1 (2), 2313:A / Sigma FT-IR 1 (2), 33:A / Structure Index 1 , 362:B:3
- Merck 14 ,4636
- [1]. Olsen, K.W., Affinity chromatography of heme-binding proteins: synthesis and characterization of hematin- and hematoporphyrin-agarose. Methods Enzymol, 1986. 123: p. 324-31.
- [1]. Olsen, K.W., Affinity chromatography of heme-binding proteins: synthesis and characterization of hematin- and hematoporphyrin-agarose. Methods Enzymol, 1986. 123: p. 324-31.
- [2]. Yuan SX, et, al. Underlying mechanism of the photodynamic activity of hematoporphyrin‑induced apop
安全信息
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 307 mg/kg TOXIC EFFECTS : Behavioral - altered sleep time (including change in righting reflex) Behavioral - ataxia Lungs, Thorax, or Respiration - other changes REFERENCE : NYKZAU Nippon Yakurigaku Zasshi. Japanese Journal of Pharmacology. (Nippon Yakuri Gakkai, c/o Kyoto Daigaku Igakubu Yakurigaku Kyoshitsu, Konoe-cho, Yoshida, Sakyo-ku, Kyoto 606, Japan) V.40- 1944- Volume(issue)/page/year: 57,219,1961
TYPE OF TEST : DNA inhibition TEST SYSTEM : Rodent - mouse Leukocyte DOSE/DURATION : 1 mg/L REFERENCE : TUMOAB Tumori. (Casa Editrice Ambrosiana, Via G. Frua 6, 20146 Milan, Italy) V.1- 1911- Volume(issue)/page/year: 67,183,1981
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