Glycidyl Phenyl Ether 环氧丙基苯基醚

CAS 122-60-1 MFCD00005133

化学结构图

122-60-1
SMILES: c1ccc(OCC2CO2)cc1

化学属性

Mol. FormulaC9H10O2
Mol. Weight150
Refractive index1.5290 to 1.5320
Boiling Point245
Density1.109
Melting Point3.5
Flash Point125°C(lit.)
TSCAYes
Vapor Density5.2 (vs air)
Vapor Pressure0.03 mmHg ( 20 °C)
Solubility2.4 G/L (20 ºC)

别名和识别编码

Chemical NameGlycidyl Phenyl Ether
CAS Number122-60-1
Alfabeta NamePHENOXYMETHYLOXIRANE 2()-
MDL NumberMFCD00005133
Synonym (2,3-epoxypropoxy)benzene (±)-Phenyl glycidyl ether 1,2-EPOXYETHYL PHENYL ETHER 1,2-Epoxy-3-phenoxypropane 1,2-Epoxy-3-phenoxypropane, 2,3-Epoxypropylphenylether 1,2-epoxy-3-phenoxy-propan 1,2-epoxy-3-phenoxy-propane 1,2-环氧-3-苯氧基丙烷 1,2-环氧-3-苯氧基丙烷 2,3-环氧丙基苯基醚 缩水甘油苯基醚 1-Phenoxy-2,3-epoxypropane 2,3-EPOXYPROPYL PHENYL ETHER 2,3-Epoxypropyl phenyl ether 2,3-环 2,3-环氧丙基苯醚 2-(PHENOXYMETHYL)OXIRANE Ether, 2,3-epoxypropyl phen Ether, phenylglycidyl Glycidylphenylether Oxirane, (phenoxymethyl)-phenol-glycidaether Phenylglycidether phenyl glycide e {} {} {} {} {Chem {} {} {} {} {Chemi {} {} {} {} {uni_hambur 环氧树脂活性稀释剂690 缩水甘油苯基醚 苯基缩水甘油醚
PubChem Substance ID31217
EC Number204-557-2
Beilstein Registry Number2744
Reaxys-RN2744
Chemical Name Translation环氧丙基苯基醚
Wiswesser Line NotationT3OTJ B1OR
LabNetwork Molecule IDLN00158191
InChIInChI=1S/C9H10O2/c1-2-4-8(5-3-1)10-6-9-7-11-9/h1-5,9H,6-7H2
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分类

  • {SNA} Epoxide Monomers, Monomers, Polymer Science, 材料科学
  • {SNA} Epoxide Monomers, Materials Science, Monomers, Polymer Science
  • {uni_hamburg} no charge; oxygen heterocycle; carbocycle; aromatic; 3ring; 6ring; ether; racemate; 1fragment

相关文献及参考

  • Beil. 17 ,V,3,13
  • Fieser 1 ,355
  • Aldrich MSDS 1 , 858:C / Corp MSDS 1 (1), 1525:A / FT-IR 2 (2), 1817:A / FT-IR 1 (1), 1064:C / FT-NMR 1 (2), 223:A / NMR-Reference 2 (1), 858:C / RegBook 1 (1), 1251:K / Sax 6 , 2189 / Structure Index 1 , 191:B:6 / Vapor Phase 3 , 996:C
  • Short: III/38B Title: Refractive Indices of Organic Liquids Author: Wohlfarth, Ch.; Wohlfarth, B. Editor: Lechner, M.D. Source: Landolt-Börnstein, New Series Volume: III/38B Year: 1996 Keyword: organic compounds; refractive index; liquids ISBN: 3-540-60596-7 ISBN: 978-3-540-60596-6 Internet Resource: DOI:10.1007/b85533 RefComment: VII, 4210 pages, Hardcover Abstract: Volume III/38 Optical Constants provides critically evaluated data on refractive indices of inorganic and organic liquids and their wavelength dependence (dispension). Part A contains the inorganic, organometallic, and organononmetallic liquids, and the binary liquid mixtures (about 900 pure substances and their mixtures). Part B contains data of more than 7600 organic liquids.
  • Short: EINECS Title: EINECS (European Inventory of Existing Commercial Chemical Substances) Source: Official Journal of the European Communities Volume: C 146 A (15.06.1990) Page: 1 Year: 1990 Internet Resource: http://ecb.jrc.ec.europa.eu/esis/index.php?PGM=ein Publish_Date: 1990/06/15

安全信息

Warnings IRRITANT 危化品目录(2015) 危险化学品
GHS Symbol
WGK Germany3
Hazard Codes 6.1 T
Hazard statements
  • H312+H332
  • H315 Causes skin irritation 会刺激皮肤
  • H317 May cause an allergic skin reaction 可能导致皮肤过敏
  • H335 May cause respiratory irritation 可能导致呼吸道刺激
  • H350 May cause cancer 可能致癌
  • H412 Harmfutoaquaticlifewithlonglastingeffects 对水生生物有害并具有长期影响。
  • H341 Suspected of causing genetic defects 怀疑导致遗传性缺陷
  • H318 Causes serious eye damage 严重伤害眼睛
  • H303 May be harmfully swallowed 吞食可能有害
Personal Protective Equipment Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter
RTECSTZ3675000
Precautionary statements
  • P201 Obtain special instructions before use. 使用前获取专门指示。
  • P202 Do not handle until all safety precautions have been read and understood. 已阅读并理解所有的安全预防措施之前,切勿操作。
  • P260 Do not breathe dust/fume/gas/mist/vapours/spray. 不要吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
  • P270 Do not eat, drink or smoke when using this product. 使用本产品时不要吃东西,喝水或吸烟。
  • P271 Use only outdoors or in a well-ventilated area.? 只能在室外或通风良好的地方使用。
  • P272 Contaminated work clothing should not be allowed out of the workplace. 污染的工作服不得带出工作场所。
  • P273 Avoid release to the environment. 避免释放到环境中。
  • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
  • P302+P352
  • P302+P352+P312+P362+P364
  • P304+P340
  • P304+P340+P312
  • P305+P351+P338+P337+P313
  • P308+P313
  • P403+P233
  • P405 Store locked up. 上锁保管。
  • P501 Dispose of contents/container to..… 处理内容物/容器.....
Signal word Danger
Risk Statements
  • R20 Harmful by inhalation 吸入有害
  • R37/38 Irritating to respiratory system and skin 对呼吸系统和皮肤有刺激性
  • R43 May cause sensitisation by skin contact 皮肤接触会产生过敏反应
  • R45 May cause cancer 可能致癌
  • R52/53
  • R68 Possible risk of irreversible effects 可能有不可挽回的作用的危险
Safety Statements
  • S45 In case of accident or if you feel unwell seek medical advice immediately (show the label where possible) 发生事故时或感觉不适时,立即求医(可能时出示标签);
  • S53 Avoid exposure - obtain special instructions before use 避免接触,使用前获得特别指示说明;
  • S61 Avoid release to the environment. Refer to special instructions/safety data sheet 避免释放到环境中,参考特别指示/安全收据说明书;
UN Number 2810
Packing GroupIII
TYPE OF TEST            : TCLo - Lowest published toxic concentration
ROUTE OF EXPOSURE       : Inhalation
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 12 ppm/6H/2Y-I
TOXIC EFFECTS :
   Tumorigenic - Carcinogenic by RTECS criteria
   Sense Organs and Special Senses (Olfaction) - tumors
REFERENCE :
   AJPAA4 American Journal of Pathology.  (Lippincott/Harper, Journal
   Fulfillment Dept., 2350 Virginia Ave., Hagerstown, MD 21740)  V.1-    1925-
   Volume(issue)/page/year: 111,140,1983

TYPE OF TEST            : LC50 - Lethal concentration, 50 percent kill
ROUTE OF EXPOSURE       : Inhalation
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : >100 ppm/4H
TOXIC EFFECTS :
   Lungs, Thorax, or Respiration - acute pulmonary edema
REFERENCE :
   AMIHAB AMA Archives of Industrial Health.  (Chicago, IL)  V.11-21, 1955-60.
   For publisher information, see AEHLAU.  Volume(issue)/page/year: 14,250,1956

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 760 mg/kg
TOXIC EFFECTS :
   Autonomic Nervous System - smooth muscle relaxant (mechanism undefined,
   spasmolytic)
REFERENCE :
   ARZNAD Arzneimittel-Forschung. Drug Research.  (Editio Cantor Verlag,
   Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.)  V.1-    1951-
   Volume(issue)/page/year: 15,1355,1965

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 3850 mg/kg
TOXIC EFFECTS :
   Behavioral - somnolence (general depressed activity)
   Behavioral - changes in motor activity (specific assay)
   Behavioral - ataxia
REFERENCE :
   AMIHAB AMA Archives of Industrial Health.  (Chicago, IL)  V.11-21, 1955-60.
   For publisher information, see AEHLAU.  Volume(issue)/page/year: 14,250,1956

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Administration onto the skin
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 1500 uL/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   AMIHBC AMA Archives of Industrial Hygiene and Occupational Medicine.
   (Chicago, IL)  V.2-10, 1950-54. For publisher information, see AEHLAU.
   Volume(issue)/page/year: 10,61,1954

TYPE OF TEST

TYPE OF TEST            : Morphological transformation
TEST SYSTEM             : Rodent - hamster Embryo
DOSE/DURATION           : 6250 ug/L
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 67,9,1979

TYPE OF TEST            : Host-mediated assay
TEST SYSTEM             : Rodent - mouse Bacteria - Salmonella typhimurium
DOSE/DURATION           : 2500 mg/kg
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 67,9,1979

TYPE OF TEST            : Mutation test systems - not otherwise specified
TEST SYSTEM             : Bacteria - Escherichia coli
DOSE/DURATION           : 300 umol/L
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 231,205,1990

TYPE OF TEST            : Mutation in microorganisms
TEST SYSTEM             : Bacteria - Escherichia coli
DOSE/DURATION           : 20 umol/L
REFERENCE :
   ARTODN Archives of Toxicology.  (Springer-Verlag, Heidelberger Pl. 3, D-1000
   Berlin 33, Fed. Rep. Ger.)  V.32-    1974-  Volume(issue)/page/year:
   46,277,1980

TYPE OF TEST            : Mutation in microorganisms
TEST SYSTEM             : Bacteria - Salmonella typhimurium
DOSE/DURATION           : 33 ug/plate
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 172,105,1986

TYPE OF TEST            : Sister chromatid exchange
TEST SYSTEM             : Rodent - hamster Lung
DOSE/DURATION           : 400 umol/L
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/pa

TYPE OF TEST            : TCLo - Lowest published toxic concentration
ROUTE OF EXPOSURE       : Inhalation
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 11 ppm/6H
SEX/DURATION            : male 19 day(s) pre-mating
TOXIC EFFECTS :
   Reproductive - Fertility - male fertility index (e.g. # males impregnating
   females per # males exposed to fertile nonpregnant females)
REFERENCE :
   TXAPA9 Toxicology and Applied Pharmacology.  (Academic Press, Inc., 1 E.
   First St., Duluth, MN 55802) V.1-    1959-  Volume(issue)/page/year:
   64,204,1982

其他信息

  • 毒性分级:中毒
  • 用途一:用作有机合成中间体。
  • 方法一:由苯酚、环氧氯丙烷在氢氧化钠存在下缩合而得。将苯酚、氢氧化钠、混合搅拌至全部溶解,冷却至5-6℃,缓缓加入环氧氯丙烷。加毕,于25℃搅拌45h,反应物用乙醚提取,提取液加无水碳酸钾干燥,过滤。滤液回收乙醚,经减压蒸馏,收集120-123℃(1.46kPa)馏分即为环氧丙基苯基醚。
  • 海关编码:29109000
  • 蒸气密度:5.2 (vs air)
  • 类别:有毒物品
  • 职业标准:TWA 6 毫克/ 立方米; STEL 60 毫克/ 立方米
  • 储运特性:库房通风低温干燥; 与食品、氧化剂分开储运
  • TCI Shanghai:环氧丙基苯基醚 Glycidyl Phenyl Ether,>;99.0%(GC)(122-60-1)
  • Acros Organics:苯基缩水甘油醚 Glycidyl phenyl ether, 99%(122-60-1)
  • MOL 文件:122-60-1.mol
  • 爆炸物危险特性:可形成过氧化物; 后者可爆
  • MSDS 信息:苯缩水甘油醚(122-60-1).msds
  • Sigma Aldrich:122-60-1(sigmaaldrich)
  • 苯基缩水甘油醚价格(试剂级):更新日期 产品编号 产品名称 包装 价格 2014/06/02 G0098 环氧丙基苯基醚 Glycidyl Phenyl Ether 25G 224元 2014/06/02 G0098 环氧丙基苯基醚 Glycidyl Phenyl Ether 500G 583元 2010/06/21 135352500 苯基缩水甘油醚 Glycidyl phenyl ether 99% 250 GR 914元
  • 可燃性危险特性:明火可燃; 遇热放出有毒蒸气
  • 急性毒性:口服-大鼠 LD50: 3850 毫克/ 公斤; 口服- 小鼠 LD50: 1400 毫克/ 公斤
  • 上游原料:碳酸钾 --> 环氧氯丙烷
  • 灭火剂:泡沫、干粉、二氧化碳、雾状水
  • Alfa Aesar:缩水甘油基苯基醚,99% Glycidyl phenyl ether, 99%(122-60-1)
  • 外观性质:无色液体。
  • 图谱信息:苯基缩水甘油醚(122-60-1)质谱(MS)
  • 蒸气压:0.03 mm Hg ( 20 °C)
  • 刺激数据:皮肤-兔子 10 毫克/ 24小时 重度; 眼睛-兔子 111 毫克 轻度

系列性分类


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