4-Chloro-7-Nitrobenzo-2-Oxa-1,3-Diazole 4-氯-7-硝基苯并-2-氧杂-1,3-二唑

CAS 10199-89-0 MFCD00005808

化学结构图

10199-89-0
SMILES: [O-][N+](=O)C1=CC=C(Cl)C2=NON=C12

化学属性

Mol. FormulaC6H2ClN3O3
Mol. Weight200
Melting Point97-99
TSCAYes
Solubility可溶
Density0.94
Stability对光敏感

别名和识别编码

Chemical Name4-Chloro-7-Nitrobenzo-2-Oxa-1,3-Diazole
CAS Number10199-89-0
Synonym 7-Chloro-4-nitro-2,1,3-benzoxadiazole NBD-chloride 4-Chloro-7-nitro-2,1,3-benzoxadiazole NBD-Cl NBD-C 1 4-氯-7-硝基-1,2,3-苯并噁二唑
PubChem Substance ID87563199
EC Number233-496-4
Beilstein Registry Number614212
MDL NumberMFCD00005808
Reaxys-RN614212
Alfabeta NameCHLORONITROBENZOXADIAZOLE 47213-----,,
Chemical Name Translation4-氯-7-硝基苯并-2-氧杂-1,3-二唑
Wiswesser Line NotationT56 BNONJ FNW IG
LabNetwork Molecule IDLN00179726
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分类

  • {SNA} Alphabetical, Benzofurazans, Carbohydrate Labels, Carbohydrate Labels for Chromatography, Derivatization Reagents, Derivatization Reagents HPLC, Derivatization Reagents TLC, Detection, Enzyme Substrates, Fluorescence, Fluorescent Indicators and Probes, Fluorescent Labels, Fluorescent Stains, Functional Group Reactive Labels, Functional Group Reactive Labels for Chromatography, Functional Group Reactive Labels for Immunoassays, Glutathione S-Transferase, Halogenated, Labels and Other Fluorophores for Membrane Research, Lipophilic and Membrane Probes, Peroxidase Substrates, Protein Stains, Protein Stains For Immunoassays,

产品应用

  • HPLC荧光标记试剂。用于高效液相色谱标记

相关文献及参考

  • Fluorogenic reagent for amines and thiols: Anal. Biochem., 53, 290 (1973).
  • Rudat, B. et al.: Eur. J. Med. Chem., 46, 4457 (2011); Michail, K. et al.: Int. J. Pharm. Pharmac. Sci., 3, 180 (2011); Walsh, M. et al.: J. Fluoresc., 21, 105 (2011);
  • Reagent for pre-column derivatization of amines: Anal. Chim. Acta, 130, 377 (1981), 170, 81 (1985); and of imino acids: Anal. Biochem., 138, 390 (1984), allowing detection after HPLC.

安全信息

GHS Symbol
WGK Germany3
Hazard Codes Xn
Hazard statements
  • H315 Causes skin irritation 会刺激皮肤
  • H301 Toxic if swallowed 吞食有毒
  • H319 Causes serious eye irritation 严重刺激眼睛
Personal Protective Equipment dust mask type N95 (US), Eyeshields, Faceshields, Gloves
RTECSDF8002400
Precautionary statements
  • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
  • P362 Take off contaminated clothing and wash before reuse. 脱掉污染的衣服，清洗后方可重新使用
  • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
  • P332+P313
  • P305+P351+P338
  • P301+P310
  • P337+P313
  • P305+P351+P338+P337+P313
Signal word
Safety Statements
  • S36/37/39 Wear suitable protective clothing, gloves and eye/face protection 穿戴适当的防护服、手套和眼睛/面保护；
  • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后，立即用大量水冲洗并征求医生意见；
  • S37 Wear suitable gloves 戴适当手套；
Risk Statements
  • R36/38 Irritating to eyes and skin 对眼睛和皮肤有刺激性
Warnings IRRITANT
Packing GroupIII
UN Number
Storage condition 储存温度2-8℃ 
TYPE OF TEST            : Mutation in microorganisms
TEST SYSTEM             : Bacteria - Salmonella typhimurium
DOSE/DURATION           : 2 ug/plate
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 88,351,1981

TYPE OF TEST            : DNA inhibition
TEST SYSTEM             : Rodent - mouse Leukocyte
DOSE/DURATION           : 4 umol/L
REFERENCE :
   CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut
   Sts., Philadelphia, PA 19106)  V.1-    1941-  Volume(issue)/page/year:
   35,3735,1975

其他信息

  • 溶于水。

系列性分类

  1. Life Science 生命科学
  2. Biochemicals and Reagents 生化试剂
  3. Fluorescent Probes, Labels, Particles and Stains - Biochemicals and Reagents
  4. Detection - Fluorescent Probes, Labels, Particles and Stains
  1. Life Science 生命科学
  2. Biochemicals and Reagents 生化试剂
  3. Luminescent Compounds/Detection - Biochemicals and Reagents
  4. Wavelength Index - Luminescent Compounds/Detection
  1. Life Science 生命科学
  2. Biochemicals and Reagents 生化试剂
  3. Fluorescent Probes, Labels, Particles and Stains - Biochemicals and Reagents
  4. Functional Group Reactive Labels - Fluorescent Probes, Labels, Particles and Stains
  5. Functional Group Reactive Labels for Immunoassays - Functional Group Reactive Labels
  1. Chemical Synthesis 化学合成
  2. Building Blocks 合成砌块
  3. Heterocyclic Building Blocks 杂环合成砌块
  4. Oxadiazoles 恶二唑
  1. Life Science 生命科学
  2. Biochemicals and Reagents 生化试剂
  3. Enzymes, Inhibitors, and Substrates - Biochemicals and Reagents
  4. Enzyme Substrates - Enzymes, Inhibitors, and Substrates
  5. Substrates by Enzyme - Enzyme Substrates
  6. Glutathione S-Transferase - Substrates by Enzyme
  1. Chemical Synthesis 化学合成
  2. Building Blocks 合成砌块
  3. Heterocyclic Building Blocks 杂环合成砌块
  4. Halogenated Heterocycles 卤代杂环
  5. Oxadiazoles - Halogenated Heterocycles
  1. Chemical Synthesis 化学合成
  2. Building Blocks 合成砌块
  3. Heterocyclic Building Blocks 杂环合成砌块
  4. Halogenated Heterocycles 卤代杂环
  5. Others
  1. Chemical Synthesis 化学合成
  2. Building Blocks 合成砌块
  3. Heterocyclic Building Blocks 杂环合成砌块
  4. Others 其他杂环
  5. Se-Containing
  1. Analytical & Chromatography 分析化学与色谱
  2. Labeling Reagents for HPLC
  1. Life Science 生命科学
  2. Biochemicals and Reagents
  3. Luminescent Compounds/Detection
  4. Chemiluminescent compounds
  1. Life Science 生命科学
  2. Biochemicals and Reagents
  3. Fluorescent Probes, Labels, Particles and Stains
  4. Functional Group Reactive Labels
  5. Functional Group Reactive Labels for Flow Cytometry
  1. Life Science 生命科学
  2. Biochemicals and Reagents
  3. Luminescent Compounds/Detection
  4. Fluorescent Probes, Labels, Particles and Stains
  5. Functional Group Reactive Labels
  6. Functional Group Reactive Labels for Flow Cytometry

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