Phthalimide 邻苯二甲酰亚胺

CAS 85-41-6 MFCD00005881

化学结构图

85-41-6
SMILES: O=C1NC(=O)c2ccccc21

化学属性

Mol. FormulaC8H5NO2
Mol. Weight147
Density1.21
Melting Point232-235
Flash Point165°(329°F)
SolubilitySoluble in water (1 mg/ml at 19.5 °C), aqueous alkali hydroxides, acetone (2.5%), and hot methanol.
TSCAYes
Boiling Point366°C

别名和识别编码

Chemical NamePhthalimide
Synonym Phthalimid 1,3-Isoindolinedione 3-二酮 邻苯二甲酰亚胺 Benzene-1,2-dicarboxylic acid imide Phthalimide 2-Diazoindan-1,3-dione 2,5-Isoindoledione 1H-Isoindole-1,3(2H)-dione Benzoimide 酞酰亚胺 Phthalsäureimid o-Phthalic imide 酞酰亚胺;异吲哚-1 酞酰亚异吲哚-1 Phenylimide o-Phthalic imide Ftalimmide 1,3-Isoindoledione Isoindole-1,3-dione Phthalic dicarboximide 酞酰亚胺,异吲哚-1 Phthalic dicarboximide; Phthalimide; Isoindole-1,3-dione 1H-isoindolinedione-1,3(2H)-dione 1H-Isoindol-1,3(2H)-dion Benzene-1,2-dicarboxylic acid imideIsoindole-1,3-dione phtalimide 3-二酮;酞酰亚异吲哚-1 1,2-Benzenedicarboximide
CAS Number85-41-6
EC Number201-603-3
Beilstein Registry Number118522
MDL NumberMFCD00005881
PubChem Substance ID87574609
Merck Number7373
Chemical Name Translation邻苯二甲酰亚胺
Reaxys-RN118522
Wiswesser Line NotationT56 BVMVJ
LabNetwork Molecule IDLN00194295
信息真实价格透明    资金保障    专业采购外包团队在线服务   
信息真实价格透明    资金保障    专业采购外包团队在线服务   
品牌质保精细包装    现货库存    一流品牌服务   

分类

  • {uni_hamburg} no charge; nitrogen heterocycle; carbocycle; aromatic; large ring; fused rings; 5ring; 6ring; 9ring; amide; lactame; 1fragment
  • {SA} Building Blocks, Carbonyl Compounds, Chemical Synthesis, Cyclic Imides, Organic Building Blocks
  • {SNA} Alphabetical Index of Analytical Standards, Analytical Standards, Analytical/Chromatography, Chromatography, Environmental Standards,
  • {SNA} Building Blocks, Carbonyl Compounds, Chemical Synthesis, Cyclic Imides, Organic Building Blocks
  • {SNA} Analytical Standards, N-P, 农残和代谢标准品, 分析/色谱, 按照字母排序
  • {SNA} All alphabetically sorted, Alphabetical Index of Analytical Standards, Analytical Standards, Analytical/Chromatography, Chromatography, Environmental Standards,

产品应用

  • A reagent used to transform allyl- and alkyl halides into protected primary amines

相关文献及参考

  • Short: II/27B
  • Merck: 14,7373
  • {
  • Merck: 14,7373 Beilstein:21,458
  • Short: II/3

安全信息

Signal word Warning
GHS Symbol
WGK Germany1
Safety Statements
  • S24/25 Avoid contact with skin and eyes 避免皮肤和眼睛接触;
Risk Statements
  • R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
Precautionary statements
  • P262 Do not get in eyes, on skin, or on clothing. 不要接触眼睛,皮肤或衣服。
  • P273 Avoid release to the environment. 避免释放到环境中。
  • P501 Dispose of contents/container to..… 处理内容物/容器.....
RTECSTI3920000
Personal Protective Equipment Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
Storage condition 密封阴凉保存。
Hazard statements
  • H303 May be harmfully swallowed 吞食可能有害
Warnings 危化品目录(2015)
TYPE OF TEST            : LD - Lethal dose
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : >500 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   NCNSA6 National Academy of Sciences, National Research Council,
   Chemical-Biological Coordination Center, Review.  (Washington, DC)
   Volume(issue)/page/year: 5,23,1953

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 5 gm/kg
TOXIC EFFECTS :
   Behavioral - somnolence (general depressed activity)
REFERENCE :
   FRPSAX Farmaco, Edizione Scientifica. (Casella Postale 227, 27100 Pavia,
   Italy)  V.8-43 1953-88 For publisher information, see FRMCE8
   Volume(issue)/page/year: 20,3,1965

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 1175 mg/kg
TOXIC EFFECTS :
   Behavioral - convulsions or effect on seizure threshold
REFERENCE :
   MEXPAG Medicina Experimentalis.  (Basel, Switzerland)  V.1-11, 1959-64;
   V.18-19, 1968-69.  For publisher information, see JNMDBO.
   Volume(issue)/page/year: 11,149,1964

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE                    : 6200 ug/kg
SEX/DURATION            : female 9 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Specific Developmental Abnormalities - other developmental
   abnormalities
REFERENCE :
   PHARAT Pharmazie.  (VEB Verlag Volk und Gesundheit, Neue Gruenstr. 18,
   Berlin DDR-1020, Ger. Dem. Rep.)  V.1-    1946-  Volume(issue)/page/year:
   31,172,1976

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE                    : 100 mg/kg
SEX/DURATION            : female 9 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Fertility - abortion
   Reproductive - Fertility - post-implantation mortality (e.g. dead and/or
   resorbed implants per total number of implants)
REFERENCE :
   PHARAT Pharmazie.  (VEB Verlag Volk und Gesundheit, Neue Gruenstr. 18,
   Berlin DDR-1020, Ger. Dem. Rep.)  V.1-    1946-  Volume(issue)/page/year:
   31,172,1976

Restrict 危险品

其他信息

  • 能升华。稍呈酸性。微溶于水、乙醚、苯和氯仿,稍溶于乙醇,易溶于碱溶液、冰醋酸和吡啶。易溶于碱性水溶液,溶于沸乙醇、沸乙酸,微溶于水,几乎不溶于苯和石油醚。

系列性分类