2-Amino-4-chloro-6-methylpyrimidine 4-chloro-6-methylpyrimidin-2-amine

CAS 5600-21-5 MFCD00006091

化学结构图

5600-21-5
SMILES: Cc1cc(Cl)nc(N)n1

化学属性

Mol. FormulaC5H6ClN3
Mol. Weight143.57
Melting Point182-186°C
TSCANo
Density1.349
Appearance 白色固体粉末,结晶(乙醇)。
Boiling Point326°C at 760 mmHg

别名和识别编码

Chemical Name2-Amino-4-chloro-6-methylpyrimidine
CAS Number5600-21-5
Alfabeta NameAMINOCHLOROMETHYLPYRIMIDINE 246-----
MDL NumberMFCD00006091
PubChem Substance ID21810
Beilstein Registry Number114297
EC Number227-018-3
Reaxys-RN114297
Synonym 4-Chloro-6-methylpyrimidin-2-amine {LY} 4-Chloro-6-methylpyrimidin-2-amine 4-amino-6-chloro-2-methylpyrimidine 4-chloro-6-methyl-2-pyridinamine {} {LY} 4-Chloro-6-methylpyrimidin-2-amine {} {} {LY} 4-Chloro-6-methylpyrimidin-2-amine {} {} {} {LY} 4-Chloro-6-methylpyrimidin-2-amine {} {} {} {} {LY} 4-Chloro-6-methylpyrimidin-2-amine {} {} {} {} {} { {} {} {} {} {} {LY} 4-Chloro-6-methylpyrimidin-2-amine {} {} {} {} {} {} {LY} 4-Chloro-6-methylpyrimidin-2-amine {} {} {} {} {} {} {} {LY} 4-Chloro-6-methylpyrimidin-2-amine {} {} {} {} {} {} {} {} {LY} 4-Chloro-6-methylpyrimidin-2-amine {} {} {} {} {} {} {} {} {} {LY} 4-Chloro-6-methylpyrimidin-2-amine {} {} {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {} {} {LY} 4-Chloro-6-methylpyrimidin-2-amine {} {} {} {} {} {} {} {} {} {} {} {LY} 4-Chloro-6-methylpyrimidin-2-amine {} {} {} {} {} {} {} {} {} {} {} {} {LY} 4-Chloro-6-methylpyrimidin-2-amine {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 4-Ch
Chemical Name Translation4-chloro-6-methylpyrimidin-2-amine
Wiswesser Line NotationT6N CNJ BZ DG F1
LabNetwork Molecule IDLN00161997
InChIInChI=1S/C5H6ClN3/c1-3-2-4(6)9-5(7)8-3/h2H,1H3,(H2,7,8,9)
Canonical SMILESNC1=NC(C)=CC(Cl)=N1
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分类

  • Building Blocks, C4 to C5, Chemical Synthesis, Halogenated Heterocycles, Heterocyclic Building Blocks, Pyrimidines
  • {uni_hamburg} no charge; nitrogen heterocycle; aromatic; 6RingOnly; 6ring; 1fragment
  • {SNA} Building Blocks, C4 to C5, Chemical Synthesis, Halogenated Heterocycles, Heterocyclic Building Blocks, Pyrimidines

产品应用

  • 主要用于合成嘧啶类青霉素和嘧啶类头孢菌素。

相关文献及参考

  • Short: EINECS
  • Short: III/5a
  • Beilstein:25(3/4)2171

安全信息

Warnings IRRITANT, AVOID SKIN CONTACT
WGK Germany3
RTECSUV6329600
Personal Protective Equipment Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
Signal word Warning
Hazard statements
  • H315 Causes skin irritation 会刺激皮肤
  • H319 Causes serious eye irritation 严重刺激眼睛
  • H335 May cause respiratory irritation 可能导致呼吸道刺激
Precautionary statements
  • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
  • P264+P265
  • P271 Use only outdoors or in a well-ventilated area.? 只能在室外或通风良好的地方使用。
  • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
  • P302+P350
  • P302+P352
  • P304+P340
  • P305+P351+P338
  • P312 Call a POISON CENTER or doctor/physician if you feel unwell. 如果你感觉不适,呼叫解毒中心或医生/医师。
  • P319
  • P321 Specific treatment (see … on this label). 具体治疗(见本标签上的)。
  • P332+P313
  • P332+P317
  • P337+P313
  • P337+P317
  • P362 Take off contaminated clothing and wash before reuse. 脱掉污染的衣服,清洗后方可重新使用
  • P362+P364
  • P403+P233
  • P405 Store locked up. 上锁保管。
  • P501 Dispose of contents/container to..… 处理内容物/容器.....
Safety Statements
  • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后,立即用大量水冲洗并征求医生意见;
  • S36/37/39 Wear suitable protective clothing, gloves and eye/face protection 穿戴适当的防护服、手套和眼睛/面保护;
  • S60 This material and its container must be disposed of as hazardous waste 该物质及其容器必须作为危险废物处置;
  • S37 Wear suitable gloves 戴适当手套;
  • S22 Do not breathe dust 不要吸入粉尘;
  • S37/39 Wear suitable gloves and eye/face protection 穿戴适当的手套和眼睛/面保护;
  • S24/25 Avoid contact with skin and eyes 避免皮肤和眼睛接触;
Risk Statements
  • R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
GHS Symbol
Hazard Codes Xi
TYPE OF TEST            : Mutation in microorganisms
TEST SYSTEM             : Microorganism - not otherwise specified
DOSE/DURATION           : 50 mg/L
REFERENCE :
   SOGEBZ Soviet Genetics.  English translation of GNKAA5.  (Plenum Pub. Corp.,
   233 Spring St., New York, NY 10013)  V.2-    1966- Volume(issue)/page/year:
   6,1623,1970

Storage condition -20°C, sealed storage, away from moisture and light {LY} -20°C, sealed storage, away from moisture and light {} {LY} -20°C, sealed storage, away from moisture and light {} {} {LY} -20°C, sealed storage, away from moisture and light {} {} {} {LY} -20°C, sealed storage, away from moisture and light {} {} {} {} {LY} -20°C, sealed storage, away from moisture and light {} {} {} {} {} {LY} -20°C, sealed storage, away from moisture and light {} {} {} {} {} {} {LY} -20°C, sealed storage, away from moisture and light {} {} {} {} {} {} {} {LY} -20°C, sealed storage, away from moisture and light {} {} {} {} {} {} {} {} {LY} -20°C, sealed storage, away from moisture and light {} {} {} {} {} {} {} {} {} {LY} -20°C, sealed storage, away from moisture and light {} {} {} {} {} {} {} {} {} {} {LY} -20°C, sealed storage, away from moisture and light {} {} {} {} {} {} {} {} {} {} {} {LY} -20°C, sealed storage, away from moisture and light {} {} {} {} {} {} {} {} {} {} {} {} {LY} -20°C

其他信息

  • Sigma Aldrich:5600-21-5(sigmaaldrich)
  • 海关编码:29335995
  • 用途二:主要用于合成嘧啶类青霉素和嘧啶类头孢菌素。
  • MSDS 信息:2-Amino-4-chloro-6-methylpyrimidine(5600-21-5).msds
  • MOL 文件:5600-21-5.mol
  • TCI Shanghai:2-氨基-4-氯-6-甲基嘧啶 2-Amino-4-chloro-6-methylpyrimidine,>;98.0%(T)(5600-21-5)
  • 检测方法:HPLC
  • 2-氨基-4-氯-6-甲基嘧啶价格(试剂级):更新日期 产品编号 产品名称 包装 价格 2014/06/02 A1088 2-氨基-4-氯-6-甲基嘧啶 2-Amino-4-chloro-6-methylpyrimidine 5G 364元 2014/06/02 A1088 2-氨基-4-氯-6-甲基嘧啶 2-Amino-4-chloro-6-methylpyrimidine 25G 999元 2010/06/21 153750250 2-氨基-4-氯-6-甲基嘧啶 2-Amino-4-chloro-6-methylpyrimidine 98% 25 GR 1650元
  • 用途一:安锥赛的中间体。
  • Acros Organics:2-氨基-4-氯-6-甲基嘧啶 2-Amino-4-chloro-6-methylpyrimidine, 98%(5600-21-5)
  • ,溶于甲醇,几乎不溶于水。
  • 上游原料:乙醚 --> 钠 --> 三氯氧磷 --> 乙酰乙酸乙酯 --> 盐酸胍
  • Alfa Aesar:2-氨基-4-氯-6-甲基嘧啶,98% 2-Amino-4-chloro-6-methylpyrimidine, 98%(5600-21-5)

系列性分类


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