2,2'-(Piperazine-1,4-diyl)diethanesulfonic acid 1,4-哌嗪二乙磺酸

CAS 5625-37-6 MFCD00006159

化学结构图

5625-37-6
SMILES: O=S(=O)(O)CCN1CCN(CCS(=O)(=O)O)CC1

化学属性

Mol. FormulaC8H18N2O6S2
Mol. Weight302.37
Density1.505
Melting Point>300 °C
TSCAYes
SolubilitySoluble in 1M NaOH (0.5 M at 20 °C), water (~1 g/L at 100 °C), and 0.5 N NaOH (0.1 M).

别名和识别编码

Chemical Name2,2'-(Piperazine-1,4-diyl)diethanesulfonic acid
MDL NumberMFCD00006159
CAS Number5625-37-6
EC Number227-057-6
Beilstein Registry Number817713
Synonym PIPES {LY} PIPES {} {LY} PIPES {} {} {LY} PIPES {} {} {} {LY} PIPES {} {} {} {} {LY} PIPES {} {} {} {} {} {LY} PIPES {} {} {} {} {} {} {LY} PIPES {} {} {} {} {} {} {} {LY} PIPES {} {} {} {} {} {} {} {} {LY} PIPES {} {} {} {} {} {} {} {} {} {LY} PIPES {} {} {} {} {} {} {} {} {} {} {LY} PIPES {} {} {} {} {} {} {} {} {} {} {} {LY} PIPES {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} PIPES {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} PIPES {} {} {} {} {} {} {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} PIPES {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} PIPES {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} PIPES {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} PIPES {} {} {} {} {} {} {} {} {} {} {}
Merck Number7479
PubChem Substance ID79723
Chemical Name Translation1,4-哌嗪二乙磺酸
Reaxys-RN817713
LabNetwork Molecule IDLN00195594
InChIInChI=1S/C8H18N2O6S2/c11-17(12,13)7-5-9-1-2-10(4-3-9)6-8-18(14,15)16/h1-8H2,(H,11,12,13)(H,14,15,16)
Canonical SMILESO=S(CCN1CCN(CCS(=O)(O)=O)CC1)(O)=O
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分类

  • {SNA} BioXtra Buffers, Buffers A to Z, Good’s Buffers, 生化试剂, 生物缓冲液
  • {SNA} BioPerformance Certified Buffers, Buffers / Buffer Salts, Buffers / Buffer salts, Buffers A to Z, Core Bioreagents, Good’s Buffers, Life Science Reagents for DNA/RNA Electrophoresis, Life Science Reagent

产品应用

  • mRNA的杂交选择 -预杂交缓冲液组分。

相关文献及参考

  • Merck: 14,7479
  • Merck: 14,7479 Beilstein:23(5)2,380
  • Biological buffer, pKa = 6.8 at 20o: Biochemistry, 5, 467 (1966).

安全信息

Signal word Warning
GHS Symbol
WGK Germany3
Safety Statements
  • S22 Do not breathe dust 不要吸入粉尘;
  • S24/25 Avoid contact with skin and eyes 避免皮肤和眼睛接触;
  • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后,立即用大量水冲洗并征求医生意见;
  • S36/37/39 Wear suitable protective clothing, gloves and eye/face protection 穿戴适当的防护服、手套和眼睛/面保护;
Risk Statements
  • R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
Precautionary statements
  • P260 Do not breathe dust/fume/gas/mist/vapours/spray. 不要吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P262 Do not get in eyes, on skin, or on clothing. 不要接触眼睛,皮肤或衣服。
  • P305+P351+P338
Personal Protective Equipment Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
Storage condition 2-8°C {LY} 2-8°C Store at RT. {} {LY} 2-8°C {} {} {LY} 2-8°C {} {} {} {LY} 2-8°C {} {} {} {} {LY} 2-8°C {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C
Hazard statements

其他信息

  • 哌嗪-N,N'-二(2-乙磺酸)价格(试剂级):更新日期 产品编号 产品名称 包装 价格 2011/08/23 xw020028 哌嗪-N,N’-二(2-乙磺酸)PIPES 50g 160元 2011/04/16 P1233 哌嗪-1,4-双(2-乙基磺酸) Piperazine-1,4-bis(2-ethanesulfonic Acid) 25G 402元 2011/04/16 P1233 哌嗪-1,4-双(2-乙基磺酸) Piperazine-1,4-bis(2-ethanesulfonic Acid) 500G 4030元
  • 海关编码:29335995
  • MOL 文件:5625-37-6.mol
  • 外观性质:白色粉末。pH range 6.1 - 7.5 pKa (25 °C) 6.8 熔点:>300℃
  • useful pH range 6.1 - 7.5 pKa (25 °C) 6.8
  • 检测方法:T
  • PIPES [piperazine-N,N′-bis(2-ethanesulfonic acid)] is frequently used as a buffering agent in biochemistry. It is an ethanesulfonic acid buffer developed by Good et al. in the 1960s. PIPES has a pKa near the physiological pH which makes it useful in cell culture work. It has been documented to minimize lipid loss when buffering glutaraldehyde histology in plant and animal tissues.
  • TCI Shanghai:哌嗪-1,4-双(2-乙基磺酸) Piperazine-1,4-bis(2-ethanesulfonic Acid),>;99.0%(T)(5625-37-6)
  • Sigma Aldrich:5625-37-6(sigmaaldrich)
  • Alfa Aesar:哌嗪-1,4-二乙磺酸,98% PIPES, 98%(5625-37-6)
  • Acros Organics:哌嗪-1,4-双(2-乙烷磺酸) PIPES, for biochemistry, 98.5+%(5625-37-6)
  • useful pH range 6.1 - 7.5
  • MSDS 信息:Piperazine-1,4-bis(2-ethanesulfonic acid)(5625-37-6).msds

系列性分类


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