2-Fluoropyridine 2-氟吡啶

CAS 372-48-5 MFCD00006224

化学结构图

372-48-5
SMILES: Fc1ccccn1

化学属性

Mol. FormulaC5H4FN
Mol. Weight97.09
Boiling Point125.9°C at 760 mmHg
Density1.128
Refractive index1.4660 to 1.4690
Flash Point28.3°C
TSCANo
Appearance 无色透明液体
pH:A

别名和识别编码

Chemical Name2-Fluoropyridine
CAS Number372-48-5
Alfabeta NameFLUOROPYRIDINE 2-
MDL NumberMFCD00006224
Synonym 2-Fluoropyridine {LY} 2-Fluoropyridine {} {LY} 2-Fluoropyridine {} {} {LY} 2-Fluoropyridine {} {} {} {LY} 2-Fluoropyridine {} {} {} {} {LY} 2-Fluoropyridine {} {} {} {} {} {LY} 2-Fluoropyridine {} {} {} {} {} {} {LY} 2-Fluoropyridine {} {} {} {} {} {} {} {LY} 2-Fluoropyridine {} {} {} {} {} {} {} {} {LY} 2-Fluoropyridine {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-Fluoropyridine {} {} {} {} {} {} {} {} {} {} {LY} 2-Fluoropyridine {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-Fluoropyridine {} {} {} {} {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-Fluoropyridine {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-Fluoropyridine {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-Fluoropyridine {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-Fluoropyridine {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2
EC Number206-757-5
Beilstein Registry Number1515
PubChem Substance ID9746
Chemical Name Translation2-氟吡啶
Reaxys-RN1515
InChIKeyMTAODLNXWYIKSO-UHFFFAOYSA-N
LabNetwork Molecule IDLN00008275
InChIInChI=1S/C5H4FN/c6-5-3-1-2-4-7-5/h1-4H
Canonical SMILESFC1=NC=CC=C1
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分类

  • {SNA} Building Blocks, C5, Chemical Synthesis, Fluorinated Building Blocks, Heterocyclic Building Blocks, Heterocyclic Fluorinated Building Blocks, Other Fluorinated Heterocycles, Pyridines
  • {uni_hamburg} no charge; nitrogen heterocycle; aromatic; 6RingOnly; 6ring; 1fragment

相关文献及参考

  • Short: II/6
  • Short: II/14a
  • Short: II/27C
  • The possibility of metallation at C-3, together with the ready nucleophilic displacement of the activated fluorine makes 2-fluoropyridine a useful precursor of a wide range of 2,3-disubstituted pyridines. See, e.g.: J. Org. Chem., 53, 2740 (1988):

安全信息

Warnings IRRITANT, FLAMMABLE
Signal word Warning
GHS Symbol
WGK Germany3
Safety Statements
  • S16 Keep away from sources of ignition - No smoking 远离火源,禁止吸烟;
  • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后,立即用大量水冲洗并征求医生意见;
  • S33 Take precautionary measures against static discharges 对静电采取预防措施;
  • S36 Wear suitable protective clothing 穿戴适当的防护服;
  • S36/37/39 Wear suitable protective clothing, gloves and eye/face protection 穿戴适当的防护服、手套和眼睛/面保护;
  • S37 Wear suitable gloves 戴适当手套;
  • S60 This material and its container must be disposed of as hazardous waste 该物质及其容器必须作为危险废物处置;
  • S7 Keep container tightly closed 保存在严格密闭容器中;
Risk Statements
  • R10 Flammable 易燃
  • R20/21/22 Harmful by inhalation, in contact with skin and if swallowed 吸入、皮肤接触和不慎吞咽有害
  • R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
Precautionary statements
  • P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking. 远离热源/火花/明火/热的表面。——禁止吸烟。
  • P240 Ground/bond container and receiving equipment. 与地面接触/连接集装箱和接受设备。
  • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
  • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
  • P303+P361+P353
  • P305+P351+P338
  • P362 Take off contaminated clothing and wash before reuse. 脱掉污染的衣服,清洗后方可重新使用
  • P501 Dispose of contents/container to..… 处理内容物/容器.....
Hazard statements
  • H226 Flammable liquid and vapour 易燃液体和蒸气
  • H315 Causes skin irritation 会刺激皮肤
  • H319 Causes serious eye irritation 严重刺激眼睛
  • H335 May cause respiratory irritation 可能导致呼吸道刺激
Personal Protective Equipment Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter
RTECSUT3900000
Packing GroupIII
UN Number 1993
Hazard Codes 3 Xn
Hazard Class3
Storage condition 2-8°C {LY} 2-8°C Flammables area {} {LY} 2-8°C {} {} {LY} 2-8°C {} {} {} {LY} 2-8°C {} {} {} {} {LY} 2-8°C {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°
TYPE OF TEST            : Mutation in microorganisms
TEST SYSTEM             : Bacteria - Salmonella typhimurium
DOSE/DURATION           : 5 mg/plate
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 176,185,1987

其他信息

  • TCI Shanghai:2-氟吡啶 2-Fluoropyridine,>;97.0%(GC)(372-48-5)
  • Hazard Note:Flammable/Irritant
  • 用途一:用作医药、农药中间体
  • MSDS 信息:2-Fluoropyridine(372-48-5).msds
  • 图谱信息:2-氟吡啶(372-48-5)核磁图( 1 HNMR) 2-氟吡啶(372-48-5)红外图谱(IR1) 2-氟吡啶(372-48-5)核磁图( 13 CNMR) 2-氟吡啶(372-48-5)质谱(MS)
  • 2-氟吡啶价格(试剂级):更新日期 产品编号 产品名称 包装 价格 2014/06/02 F0217 2-氟吡啶 2-Fluoropyridine 25G 526元 2010/06/21 119630500 2-氟吡啶 2-Fluoropyridine 98% 50 ML 1494元 2010/06/21 119632500 2-氟吡啶 2-Fluoropyridine 98% 250 ML 5227元
  • Acros Organics:2-氟吡啶 2-Fluoropyridine, 98%(372-48-5)
  • 海关编码:29333999
  • MOL 文件:372-48-5.mol
  • 下游产品:2-(5-溴-2-噻酚)吡啶 --> 2-氟-3-吡啶硼酸
  • Alfa Aesar:2-氟吡啶,99% 2-Fluoropyridine, 99%(372-48-5)
  • Sigma Aldrich:372-48-5(sigmaaldrich)

系列性分类