4-Hydroxy-2,2,6,6-tetramethyl-piperidinooxy 哌啶醇氧化物

CAS 2226-96-2 MFCD00006478

化学结构图

2226-96-2
SMILES: CC1(C)CC(O)CC(C)(C)N1[O]

化学属性

Mol. FormulaC9H18NO2
Mol. Weight172.24
Melting Point69-71 °C
Flash Point146°(295°F)
TSCAYes
Density1.187
Solubility易溶于乙醇、苯等有机溶剂，易溶于水。
Boiling Point302.58 °C at 760 mmHg

别名和识别编码

Chemical Name4-Hydroxy-2,2,6,6-tetramethyl-piperidinooxy
CAS Number2226-96-2
Synonym Tempol {LY} Tempol {} {LY} Tempol {} {} {LY} Tempol {} {} {} {LY} Tempol {} {} {} {} {LY} Tempol {} {} {} {} {} {LY} Tempol {} {} {} {} {} {} {LY} Tempol {} {} {} {} {} {} {} {LY} Tempol {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Tempol {} {} {} {} {} {} {} {} {} {LY} Tempol {} {} {} {} {} {} {} {} {} {} {LY} Tempol {} {} {} {} {} {} {} {} {} {} {} {LY} Tempol {} {} {} {} {} {} {} {} {} {} {} {} {LY} Tempol {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Tempol {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Tempol {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Tempol {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Tempol {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Tempol {} {} {} {} {} {} {} {} {} {} {} {}
MDL NumberMFCD00006478
Beilstein Registry Number1422990
EC Number218-760-9
PubChem Substance ID87571222
Reaxys-RN11328213
Merck Number9141
Chemical Name Translation哌啶醇氧化物
LabNetwork Molecule IDLN00188889
Canonical SMILES[O]N1C(C)(C)CC(O)CC1(C)C
信息真实价格透明    资金保障    专业采购外包团队在线服务   
信息真实价格透明    资金保障    专业采购外包团队在线服务   
品牌质保精细包装    现货库存    一流品牌服务   

分类

  • {SNA} Chemical Synthesis, Radical Chemistry, Stable Radicals, Synthetic Reagents, TEMPO Derivatives
  • {uni_hamburg} no charge; nitrogen heterocycle; alicycle; 6RingOnly; 6ring; alcohol; 1fragment
  • {SNA} Electron Spin Resonance (ESR/EPR) Spectroscopy, Spectroscopy, Spin Labels, 分析/色谱, 分析试剂
  • Analytical Reagents, Analytical/Chromatography, Chemical Synthesis, Electron Spin Resonance (ESR/EPR) Spectroscopy, Radical Chemistry, Spectroscopy, Spin Labels, Stable Radicals, Synthetic Reagents, TEMPO Derivatives
  • {SNA} Analytical Reagents, Analytical/Chromatography, Electron Spin Resonance (ESR/EPR) Spectroscopy, Spectroscopy, Spin Labels
  • {SNA} Chemical Synthesis,
  • {SNA} Chemical Synthesis,

产品应用

  • A free radical scavenger

相关文献及参考

  • [2]. Chatterjee PK, et al. Tempol, a membrane-permeable radical scavenger, reduces oxidant stress-mediated renal dysfunction and injury in the rat. Kidney Int. 2000 Aug;58(2):658-73.
  • Compare also 4-Acetamido-TEMPO, B23456 and TEMPO, A12733.
  • Flather, M., et al.: Lancet, 355, 1575 (2000),
  • Merck 14 ,9141
  • Merck:9141
  • Merck:9141 Beilstein: 21,1,161
  • Perez, M. J., Cederbaum, A. I., Spin trapping agents (Tempol and POBN) protect HepG2 cells overexpressing CYP2E1 against arachidonic acid toxicity. Free Radic. Biol. Med. 30 , 734, (2001) 摘要
  • Recommended as a stabilizer (antioxidant) for the protection of unsaturated fatty acids and their derivatives: J. Am. Chem. Soc., 101, 6748 (1979
  • Recommended as a stabilizer (antioxidant) for the protection of unsaturated fatty acids and their derivatives: J. Am. Chem. Soc., 101, 6748 (1979).
  • Reviews: Synthesis and reactions of stable nitroxyl radicals: Synthesis, 190, 401 (1971); Ad

安全信息

Precautionary statements
  • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
  • P270 Do not eat, drink or smoke when using this product. 使用本产品时不要吃东西，喝水或吸烟。
  • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
  • P301+P312
  • P301+P312+P330
  • P302+P352
  • P302+P352+P332+P313+P362+P364
  • P305+P351+P338
  • P305+P351+P338+P337+P313
  • P332+P313
  • P362 Take off contaminated clothing and wash before reuse. 脱掉污染的衣服，清洗后方可重新使用
  • P501 Dispose of contents/container to..… 处理内容物/容器.....
GHS Symbol
WGK Germany1
Signal word Warning
Hazard statements
  • H315 Causes skin irritation 会刺激皮肤
  • H335 May cause respiratory irritation 可能导致呼吸道刺激
  • H302 Harmful if swallowed 吞食有害
  • H319 Causes serious eye irritation 严重刺激眼睛
RTECSTN8991000
Hazard Codes Xn
Personal Protective Equipment dust mask type N95 (US), Eyeshields, Gloves
Safety Statements
  • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后，立即用大量水冲洗并征求医生意见；
  • S36 Wear suitable protective clothing 穿戴适当的防护服；
  • S36/3/39
  • S37/39 Wear suitable gloves and eye/face protection 穿戴适当的手套和眼睛/面保护；
  • S60 This material and its container must be disposed of as hazardous waste 该物质及其容器必须作为危险废物处置；
Risk Statements
  • R22 Harmful if swallowed 吞咽有害
  • R36/38 Irritating to eyes and skin 对眼睛和皮肤有刺激性
Storage condition Store at room temperature {LY} Store at room temperature {} {LY} Store at room temperature {} {} {LY} Store at room temperature {} {} {} {LY} Store at room temperature {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 1053 mg/kg
TOXIC EFFECTS :
   Sense Organs and Special Senses (Eye) - effect, not otherwise specified
   Behavioral - convulsions or effect on seizure threshold
   Lungs, Thorax, or Respiration - dyspnea
REFERENCE :
   NTIS** National Technical Information Service.  (Springfield, VA 22161)
   Formerly U.S. Clearinghouse for Scientific & Technical Information.
   Volume(issue)/page/year: OTS0536225

TYPE OF TEST            : Mutation in microorganisms
TEST SYSTEM             : Bacteria - Salmonella typhimurium
DOSE/DURATION           : 24 umol/plate
REFERENCE :
   ABBIA4 Archives of Biochemistry and Biophysics.  (Academic Press, Inc., 1 E.
   First St., Duluth, MN 55802)  V.31-    1951-  Volume(issue)/page/year:
   251,393,1986

其他信息

  • 外观性质:桔黄色片状固体或结晶。
  • Acros Organics:4-羟基-2,2,6,6-四甲基哌啶氧 4-Hydroxy-2,2,6,6-tetramethyl-piperidinooxy, free radical, 98%(2226-96-2)
  • MOL 文件:3637-10-3.mol
  • 用途二:该品对丙烯酸酯类、甲基丙烯酸酯类、丙烯酸、丙烯腈、苯乙烯、丁二烯有较好的阻聚效果。其阻聚性能优于酚类、芳胺类、醚类、醌类和硝基化合物等阻聚剂。
  • 用途三:本品适用于防止烯烃类单位的生产，分离,精制,储存或者运输过程中的自聚,控制和调节烯烃类及其衍生物在有机合成反应中的聚合度。
  • 存储方法:易吸潮，需在密闭干燥条件下储存、防高温，应保持包装的完整，存于通风，整洁的库房，避免与其它酸性化学品存放。
  • Sigma Aldrich:2226-96-2(sigmaaldrich)
  • Alfa Aesar:4-羟基-2,2,6,6-四甲基哌啶-1-氧自由基,98+% 4-Hydroxy-TEMPO, free radical, 98+%(2226-96-2)
  • TCI Shanghai:4-羟基-2,2,6,6-四甲基哌啶-1-氧基自由基 4-Hydroxy-2,2,6,6-tetramethylpiperidine 1-Oxyl Free Radical,>;98.0%(GC)(2226-96-2)
  • MOL 文件:2226-96-2.mol
  • MSDS 信息:2,2,6,6-Tetramethyl freeagaoxy-4-piperidyl(2226-96-2).msds
  • 阻聚剂701价格(试剂级):更新日期 产品编号 产品名称 包装 价格 2014/06/02 H0865 4-羟基-2,2,6,6-四甲基哌啶1-氧基自由基 4-Hydroxy-2,2,6,6-tetramethylpiperidine 1-Oxyl Free Radical 25G 580元 2014/06/02 H0865 4-羟基-2,2,6,6-四甲基哌啶1-氧基自由基 4-Hydroxy-2,2,6,6-tetramethylpiperidine 1-Oxyl Free Radical 5G 175元 2010/06/21 175050010 4-羟基-2,2,6,6-四甲基哌啶-1-氧自由基 4-Hydroxy-2,2,6,6-tetramethyl-piperidinooxy 98%, free radical 1 GR 247元
  • 海关编码:29333999
  • 储存注意事项:阻聚剂701易吸潮，需在密闭干燥条件下储存、防高温，应保持包装的完整，存于通风，整洁的库房，避免与其它酸性化学品存放。
  • 高效阻聚剂系列:高效阻聚剂ZJ-705 高效阻聚剂ZJ-701氮氧自由基 对羟基苯甲醚 N-N二正丁基二硫代氨基甲酸铜 吩噻嗪（硫代二苯胺） 醋酸铜 对苯二酚
  • 用途一:用于防止烯烃单体在生产、分离、精制、储存或者运输过程中的自聚，控制和调节烯烃类及其衍生物的聚合度

系列性分类

  1. Chemical Synthesis 化学合成
  2. Building Blocks 合成砌块
  3. Heterocyclic Building Blocks 杂环合成砌块
  4. Homopiperidines 同哌啶
  1. Chemical Synthesis 化学合成
  2. Building Blocks 合成砌块
  3. Heterocyclic Building Blocks 杂环合成砌块
  4. Piperidines 哌啶
  1. Analytical & Chromatography 分析化学与色谱
  2. Analytical Reagents
  3. Spectroscopy - Analytical Reagents
  4. Electron Spin Resonance (ESR/EPR) Spectroscopy - Spectroscopy
  5. Spin Labels - Electron Spin Resonance (ESR/EPR) Spectroscopy
  1. Chemical Synthesis 化学合成
  2. Synthetic Reagents 合成试剂
  3. Radical Chemistry - Synthetic Reagents
  4. Stable Radicals - Radical Chemistry
  5. TEMPO Derivatives - Stable Radicals
  1. Chemical Synthesis 化学合成
  2. Synthetic Reagents 合成试剂
  3. Radical Chemistry - Synthetic Reagents
  4. Stable Radicals - Radical Chemistry
  5. TEMPO Derivatives - Stable Radicals
  1. Analytical & Chromatography 分析化学与色谱
  2. ESR Spectrometry
  1. Chemical Synthesis 化学合成
  2. Synthetic Reagents 合成试剂
  3. Radical Chemistry - Synthetic Reagents
  4. Stable Radicals
  5. Others
  1. Medical Research Areas
  2. Metabolism
  3. Reactive Oxygen Species  (活性氧)

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