Quinoxaline 喹喔啉

CAS 91-19-0 MFCD00006719

化学结构图

91-19-0
SMILES: c1ccc2nccnc2c1

化学属性

Mol. FormulaC8H6N2
Mol. Weight130.15
Density1.124
Boiling Point229.5°C at 760 mmHg
Melting Point29-32°C
Flash Point98°(208°F)
TSCAYes
Solubility可溶
Appearance 白色结晶。熔点28℃(29-30℃),沸点229℃,140℃(5.33kPa),108-110℃(1.6kPa),相对密度1.1334(40/4℃),折光率1.6231(40℃)。易溶于水、醇、醚、苯。该品的一水合物熔点37℃。

别名和识别编码

Chemical NameQuinoxaline
CAS Number91-19-0
Alfabeta NameQUINOXALINE
MDL NumberMFCD00006719
EC Number202-047-4
Beilstein Registry Number109351
Synonym Quinoxaline {LY} Quinoxaline {} {LY} Quinoxaline {} {} {LY} Quinoxaline {} {} {} {LY} Quinoxaline {} {} {} {} {LY} Quinoxaline {} {} {} {} {} {LY} Quinoxaline {} {} {} {} {} {} {LY} Quinoxaline {} {} {} {} {} {} {} {LY} Quinoxaline {} {} {} {} {} {} {} {} {LY} Quinoxaline {} {} {} {} {} {} {} {} {} {LY} Quinoxaline {} {} {} {} {} {} {} {} {} {} {LY} Quinoxaline {} {} {} {} {} {} {} {} {} {} {} {LY} Quinoxaline {} {} {} {} {} {} {} {} {} {} {} {} {LY} Quinoxaline {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Quinoxaline {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Quinoxaline {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Quinoxaline {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Quinoxaline {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Quinoxaline {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Quinoxaline {} {} {} {} {} {} {} {} {} {}
PubChem Substance ID87575557
Merck Number8078
Reaxys-RN109351
Chemical Name Translation喹喔啉
Wiswesser Line NotationT66 BN ENJ
LabNetwork Molecule IDLN00010378
InChIInChI=1S/C8H6N2/c1-2-4-8-7(3-1)9-5-6-10-8/h1-6H
Canonical SMILESC12=CC=CC=C1N=CC=N2
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分类

  • {uni_hamburg} no charge; nitrogen heterocycle; carbocycle; aromatic; large ring; fused rings; 6ring; 10ring; 1fragment
  • {SNA} Additional Standards, All alphabetical sorted, Analytical Standards, Antibiotics Standards, Chemical Structure, Chromatography, Clinical Standards, Colorant Standards, Colors, Food and Cosmetic Component Standards, Organic Pollutant Standards, Others, Q-Z, Volatile & Semivolatile Standards, 分析/色谱
  • {SNA} All alphabetical sorted, Analytical Standards, Analytical/Chromatography, Antibiotics, Chemical Structure,
  • {SNA} Building Blocks, Chemical Synthesis, Heterocyclic Building Blocks, Quinoxalines

相关文献及参考

  • Short: II/3 Title: Luminescence of Organic Substances Author: Schmillen, A.; Legler, R. Editor: Hellwege, K.-H.; Hellwege, A.M. Source: Landolt-Börnstein, New Series Volume: II/3 Year: 1967 ISBN: 3-540-03895-7 ISBN: 978-3-540-03895-5 Internet Resource: DOI:10.1007/b86158 RefComment: 270 figs., VIII, 416 pages. Hardcover Abstract: For more than 1000 luminescent organic substances the most important data are represented as wave numbers of absorption and emission bands, decay times and quantum efficiencies. Additional tables contain further information for restricted groups of substances (figures on typical spectra, wave numbers of sharp single bands, influence of surrounding molecules, etc.).
  • Short: III/20a Title: Nuclear Quadrupole Resonance Spectroscopy Data: Nuclei D ... Cl Author: Chihara, H.; Nakamura, N. Editor: Hellwege, K.-H.; Hellwege, A.M. Source: Landolt-Börnstein, New Series Volume: III/20a Year: 1988 Keyword: NQR ISBN: 3-540-18161-X ISBN: 978-3-540-18161-3 Internet Resource: DOI:10.1007/b31153 RefComment: IX,677 pages. Hardcover Abstract: Nuclear Quadrupole Resonance Spectroscopy has become a standard method for structural research in molecular and solid state physics as well as for different branches of chemistry. The volumes cover data for more than 8,000 substances in the solid state. Data for free molecules have been published in volumes II/14 and II/15 of the New Series. The tables are arranged according to the atomic number of the elements.
  • Short: III/35B Title: Nuclear Magnetic Resonance (NMR) Data: Chemical Shifts and Coupling Constants for Fluorine-19 and Nitrogen-15 Author: Balasubramanian, M.; Gupta, R.R.; Jain, M.; Perumal, S. Editor: Gupta, R.R.; Lechner, M.D. Source: Landolt-Börnstein, New Series Volume: III/35B Year: 1998 ISBN: 3-540-63275-1 ISBN: 978-3-540-63275-7 Internet Resource: DOI:10.1007/b55685 RefComment: VII, 242 pages. With CD-ROM. Hardcover Abstract: This volume provides a comprehens

安全信息

Warnings IRRITANT
Signal word Warning
GHS Symbol
WGK Germany3
Safety Statements
  • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后,立即用大量水冲洗并征求医生意见;
  • S36 Wear suitable protective clothing 穿戴适当的防护服;
  • S36/37/39 Wear suitable protective clothing, gloves and eye/face protection 穿戴适当的防护服、手套和眼睛/面保护;
  • S37 Wear suitable gloves 戴适当手套;
Risk Statements
  • R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
Precautionary statements
  • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
  • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
  • P302+P352+P332+P313+P362+P364
  • P305+P351+P338
  • P305+P351+P338+P337+P313
  • P362 Take off contaminated clothing and wash before reuse. 脱掉污染的衣服,清洗后方可重新使用
Hazard statements
  • H315 Causes skin irritation 会刺激皮肤
  • H319 Causes serious eye irritation 严重刺激眼睛
  • H335 May cause respiratory irritation 可能导致呼吸道刺激
Personal Protective Equipment dust mask type N95 (US), Eyeshields, Gloves
RTECSVD1225000
Hazard Codes Xi
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 250 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   NTIS** National Technical Information Service.  (Springfield, VA 22161)
   Formerly U.S. Clearinghouse for Scientific & Technical Information.
   Volume(issue)/page/year: AD607-952

Storage condition Store at room temperature {LY} Store at room temperature {} {LY} Store at room temperature {} {} {LY} Store at room temperature {} {} {} {LY} Store at room temperature {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {}

其他信息

  • TCI Shanghai:喹喔啉 Quinoxaline,>;99.0%(GC)(91-19-0)
  • MSDS 信息:Quinoxaline(91-19-0).msds
  • Acros Organics:喹诺西林 Quinoxaline, 99%(91-19-0)
  • MOL 文件:91-19-0.mol
  • Alfa Aesar:喹喔啉,98+% Quinoxaline, 98+%(91-19-0)
  • 方法一:由邻苯二胺与乙二醛经环合而得。在反应锅中加水,投入亚硫酸氢钠,搅拌,慢慢加入乙二醛,温度上升到75-80℃,析出白色结晶。继续搅拌10min,再加水及邻苯二胺,于75-80℃保温1h。冷却至50℃,用碳酸钠中和至pH=8,加热至60℃,静置后分去水层,即得含量80%的苯并吡嗪,收率90%。
  • Hazard Note:Irritant
  • 海关编码:29339990
  • 下游产品:奥拉多司 --> 2,3-吡嗪二羧酸 --> 2,3-吡嗪二酸酐
  • 图谱信息:喹喔啉(91-19-0)质谱(MS) 喹喔啉(91-19-0)核磁图( 13 CNMR) 喹喔啉(91-19-0)核磁图( 1 HNMR)
  • 喹喔啉价格(试剂级):更新日期 产品编号 产品名称 包装 价格 2014/06/02 Q0020 喹喔啉 Quinoxaline 25G 493元 2010/06/21 132225000 喹喔啉 Quinoxaline 99% 500 GR 2465元 2010/06/21 132221000 喹喔啉 Quinoxaline 99% 100 GR 624元
  • Sigma Aldrich:91-19-0(sigmaaldrich)
  • 用途一:用作抗结核药物吡嗪酰胺的中间体。
  • 上游原料:亚硫酸氢钠 --> 1,2-苯二胺 --> 乙二醛

系列性分类


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