CAS 485-71-2 MFCD00006783-(-)-Cinchonidine 辛可尼定 -LabNovo

(-)-Cinchonidine 辛可尼定

CAS 485-71-2 MFCD00006783

化学结构图

SMILES: C=C[C@H]1CN2CC[C@H]1C[C@H]2[C@H](O)c1ccnc2ccccc12

化学属性

Mol. Formula	C19H22N2O
Mol. Weight	294.39
Density	1.2
Melting Point	204-206°C
TSCA	Yes
Solubility	不溶
Refractive index	-107.5 ° (C=1, EtOH)
Boiling Point	464.5°C at 760 mmHg

别名和识别编码

Chemical Name	Cinchonidine
CAS Number	485-71-2
Synonym	Cinchonidine {LY} Cinchonidine cinchonidine cinchonidine hydrochloride cinchonidine monohydrochloride cinchonidine sulfate(2:1) cinchonidine, (1beta,3alpha,4beta,8alpha,9R)-isomer {} {LY} Cinchonidine {} {} {LY} Cinchonidine {} {} {} {LY} Cinchonidine {} {} {} {} {LY} Cinchonidine {} {} {} {} {} {LY} Cinchonidine {} {} {} {} {} {} {LY} Cinchonidine {} {} {} {} {} {} {} {LY} Cinchonidine {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Cinchonidine {} {} {} {} {} {} {} {} {} {LY} Cinchonidine {} {} {} {} {} {} {} {} {} {} {LY} Cinchonidine {} {} {} {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {} {} {} {LY} Cinchonidine {} {} {} {} {} {} {} {} {} {} {} {} {LY} Cinchonidine {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Cinchonidine {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Cinchonidine {} {} {} {} {} {} {} {} {} {} {
MDL Number	MFCD00006783
EC Number	207-622-3
Beilstein Registry Number	89690
PubChem Substance ID	101744
Merck Number	2286
Reaxys-RN	5286475
Chemical Name Translation	辛可尼定
Wiswesser Line Notation	T66 BNJ EYQ- DT66 A B CNTJ A1U1
LabNetwork Molecule ID	LN01352347
InChI	InChI=1S/C19H22N2O/c1-2-13-12-21-10-8-14(13)11-18(21)19(22)16-7-9-20-17-6-4-3-5-15(16)17/h2-7,9,13-14,18-19,22H,1,8,10-12H2/t13-,14-,18-,19+/m0/s1
Canonical SMILES	C=C[C@H]1C[N@](CC[C@H]1C2)[C@]2([H])[C@H](O)C3=CC=NC4=CC=CC=C34

信息真实价格透明资金保障专业采购外包团队在线服务

品牌质保精细包装现货库存一流品牌服务

产品应用

Occurs in most varieties of Cinchona

安全信息

Signal word Warning

GHS Symbol

WGK Germany3

Safety Statements

S36/37 Wear suitable protective clothing and gloves 穿戴适当的防护服和手套；

Risk Statements

R20/21/22 Harmful by inhalation, in contact with skin and if swallowed 吸入、皮肤接触和不慎吞咽有害
R22 Harmful if swallowed 吞咽有害
R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
R43 May cause sensitisation by skin contact 皮肤接触会产生过敏反应
R48/22
R63 Possible risk of harm to the unborn child 可能危害未出生婴儿

Precautionary statements

P201 Obtain special instructions before use. 使用前获取专门指示。
P202 Do not handle until all safety precautions have been read and understood. 已阅读并理解所有的安全预防措施之前，切勿操作。
P203
P260 Do not breathe dust/fume/gas/mist/vapours/spray. 不要吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
P270 Do not eat, drink or smoke when using this product. 使用本产品时不要吃东西，喝水或吸烟。
P271 Use only outdoors or in a well-ventilated area.? 只能在室外或通风良好的地方使用。
P272 Contaminated work clothing should not be allowed out of the workplace. 污染的工作服不得带出工作场所。
P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
P281 Use personal protective equipment as required. 使用所需的个人防护装备。
P301+P312
P301+P312+P330
P301+P317
P302+P352
P304+P312
P304+P340
P308+P313
P312 Call a POISON CENTER or doctor/physician if you feel unwell. 如果你感觉不适，呼叫解毒中心或医生/医师。
P314 Get medical advice/attention if you feel unwell. 获取医疗咨询/就医，如果你觉得不舒服
P317
P318
P319
P321 Specific treatment (see … on this label). 具体治疗（见本标签上的）。
P330 Rinse mouth. 漱口
P333+P313
P333+P317
P362+P364
P363 Wash contaminated clothing before reuse. 被污染的衣服洗净后方可重新使用。
P405 Store locked up. 上锁保管。
P501 Dispose of contents/container to..… 处理内容物/容器.....

Hazard statements

H302 Harmful if swallowed 吞食有害
H317 May cause an allergic skin reaction 可能导致皮肤过敏
H332 Harmful if inhaled 吸入有害
H361 Suspected of damaging fertility or the unborn child 怀疑对生育能力或未出生婴儿造成伤害
H361d Suspected of damaging the unborn child 怀疑对未出生婴儿造成伤害
H373 May causes damage to organs through prolonged or repeated exposure 长期或频繁接触可能会损伤器官

Personal Protective Equipment Eyeshields, Faceshields, Gloves, type N95 (US), type P1 (EN143) respirator filter

RTECSGD2975000

Storage condition 2-8°C, protect from light, stored under nitrogen {LY} 2-8°C, protect from light, stored under nitrogen Light Sensitive {} {LY} 2-8°C, protect from light, stored under nitrogen {} {} {LY} 2-8°C, protect from light, stored under nitrogen {} {} {} {LY} 2-8°C, protect from light, stored under nitrogen {} {} {} {} {LY} 2-8°C, protect from light, stored under nitrogen {} {} {} {} {} {LY} 2-8°C, protect from light, stored under nitrogen {} {} {} {} {} {} {LY} 2-8°C, protect from light, stored under nitrogen {} {} {} {} {} {} {} {LY} 2-8°C, protect from light, stored under nitrogen {} {} {} {} {} {} {} {} {LY} 2-8°C, protect from light, stored under nitrogen {} {} {} {} {} {} {} {} {} {LY} 2-8°C, protect from light, stored under nitrogen {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C, protect from light, stored under nitrogen {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C, protect from light, stored under nitrogen {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C, protect from l

Hazard Codes 6.1 Xn Xn,Xi

Packing GroupIII

UN Number 1544

Hazard Class6.1(b)

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Bird - quail
DOSE/DURATION           : >316 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   EESADV Ecotoxicology and Environmental Safety.  (Academic Press, Inc., 1 E.
   First St., Duluth, MN 55802)  V.1-    1977-  Volume(issue)/page/year:
   6,149,1982

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 206 mg/kg
TOXIC EFFECTS :
   Behavioral - somnolence (general depressed activity)
   Behavioral - muscle contraction or spasticity
REFERENCE :
   APTOA6 Acta Pharmacologica et Toxicologica.  (Copenhagen, Denmark)  V.1-59,
   1945-86.  For publisher information, see PHTOEH  Volume(issue)/page/year:
   4,265,1948

其他信息

Alfa Aesar:辛可尼丁,99% (-)-Cinchonidine, 99% (total base), may cont. up to 5% quinine(485-71-2)
海关编码:29392900
MSDS 信息:L-Cinchonidine(485-71-2).msds
Acros Organics:辛可尼丁/4-喹啉基-(5-乙烯基-1-氮杂双环[2.2.2]辛烷-2-基)甲醇 Cinchonidine, 98.5-101%(485-71-2)
Sigma Aldrich:485-71-2(sigmaaldrich)
图谱信息:辛可尼丁(485-71-2)质谱(MS) 辛可尼丁(485-71-2)红外图谱(IR1) 辛可尼丁(485-71-2)红外图谱(IR2) 辛可尼丁(485-71-2)核磁图( 13 CNMR)
下游产品:(S)-7,7'-双[二(3,5-二甲基苯基羟亚磷基))-1,1'-螺二氢茚 --> (R)-7,7'-二联苯羟亚膦-1,1'-螺旋菌 --> (S)-1,1-螺二氢茚-7,7-二酚 --> (11AR)-(+)-10,11,12,13-四氢茚并[7,1-DE:1',7'-FG][1,3,2]二氧磷-5-双[-1-苯乙基]胺 --> 苯基-[R-1,1-螺二氢茚-7,7-二基]-亚磷酸酯 --> N-二甲基-1，1-螺旋茚丹-7，7-二基磷铵 --> 消旋螺环二酚(RAC-1) --> 二氯[1,1'-双(耳叔丁基膦)二茂铁钯(II) ]PALLADIUM(II) --> 1,1'-双(二叔丁基膦)二茂铁 --> 2-(二环己基膦基)联苯 --> S-氰戊菊酯 --> 奎宁硫酸盐 --> 福辛普利 --> 贝那普利 --> N-苄基氯化辛可宁丁
TCI Shanghai:辛可尼定 Cinchonidine,>;98.0%(T)(485-71-2)
辛可尼丁价格(试剂级):更新日期产品编号产品名称包装价格 2011/04/16 C0347 辛可尼定 Cinchonidine 25G 771元 2011/04/16 C0347 辛可尼定 Cinchonidine 250G 5280元 2010/06/21 110331000 辛可尼丁 Cinchonidine 98.5-101% 100 GR 1319元
不溶于水，溶于醇和氯仿。
辛可尼丁价格(试剂级):更新日期产品编号产品名称包装价格 2014/06/02 C0347 辛可尼定 Cinchonidine 25G 707元 2014/06/02 C0347 辛可尼定 Cinchonidine 250G 5100元 2010/06/21 110331000 辛可尼丁 Cinchonidine 98.5-101% 100 GR 1319元
敏感性:Light Sensitive
比旋光度:-115 ° (c=1, EtOH)
存储注意事项:光敏感
MOL 文件:485-71-2.mol