2,6-Dichloro-4-Nitroaniline 2,6-二氯-4-硝基苯胺

CAS 99-30-9 MFCD00007677

化学结构图

99-30-9
SMILES: Nc1c(Cl)cc([N+](=O)[O-])cc1Cl

化学属性

Mol. FormulaC6H4Cl2N2O2
Mol. Weight207.01
Melting Point190-192 °C
TSCAYes
Boiling Point130 °C at 2 mmHg
Flash Point149.1±26.5 °C
Solubility1 g/L (60 °C)
Density1.624

别名和识别编码

Chemical Name2,6-Dichloro-4-Nitroaniline
MDL NumberMFCD00007677
CAS Number99-30-9
Synonym 2,6-Dichloro-4-nitroaniline {LY} 2,6-Dichloro-4-nitroaniline {} {LY} 2,6-Dichloro-4-nitroaniline {} {} {LY} 2,6-Dichloro-4-nitroaniline {} {} {} {LY} 2,6-Dichloro-4-nitroaniline {} {} {} {} {LY} 2,6-Dichloro-4-nitroaniline {} {} {} {} {} {LY} 2,6-Dichloro-4-nitroaniline {} {} {} {} {} {} {LY} 2,6-Dichloro-4-nitroaniline {} {} {} {} {} {} {} {LY} 2,6-Dichloro-4-nitroaniline {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2,6-Dichloro-4-nitroaniline {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {} {LY} 2,6-Dichloro-4-nitroaniline {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2,6-Dichloro-4-nitroaniline {} {} {} {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {} {} {} {LY} 2,6-Dichloro-4-nitroaniline {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2,6-Dichloro-4-nitroaniline {} {} {} {} {} {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2,6-Dichloro-4-nitroaniline
PubChem Substance ID87567068
Beilstein Registry Number1459581
EC Number202-746-4
Chemical Name Translation2,6-二氯-4-硝基苯胺
Reaxys-RN1459581
Wiswesser Line NotationZR BG FG DNW
LabNetwork Molecule IDLN00225197
InChIInChI=1S/C6H4Cl2N2O2/c7-4-1-3(10(11)12)2-5(8)6(4)9/h1-2H,9H2
Canonical SMILESNC1=C(C=C([N+]([O-])=O)C=C1Cl)Cl
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分类

  • {SNA} All Fungicides, Analytical Standards, Aromatics, D, Fungicides, 农残和代谢标准品, 分析/色谱, 按照字母排序
  • {SNA} Amines, Building Blocks, C6, Chemical Synthesis, Nitrogen Compounds,

产品应用

  • 用作重要的染料中间体,用于分散黄棕3GL、分解黄棕2RFL、分散棕3R、分散棕5R。在50年代末期,开始作为杀菌剂商品出售。作为广谱性农用杀菌剂,可防治甘薯、洋麻、黄瓜、莴苣、棉花、烟草、草莓、马铃薯等的菌核病;甘薯、棉花及桃子的软腐病;马铃薯和西红柿的晚疫病;杏、扁桃及苹果的枯萎病;小麦的黑穗病;蚕豆花腐病。氯硝胺可与大多数杀虫剂、杀菌剂、波尔多合剂及石灰硫磺等混配使用。

相关文献及参考

  • Beilstein:12,735

安全信息

RTECSBX2975000
GHS Symbol
Precautionary statements
  • P260 Do not breathe dust/fume/gas/mist/vapours/spray. 不要吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
  • P273 Avoid release to the environment. 避免释放到环境中。
  • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
  • P284 Wear respiratory protection.? 佩戴呼吸保护装置。
  • P301+P310
  • P302+P350
  • P302+P352+P332+P313+P362+P364
  • P305+P351+P338+P337+P313
  • P312 Call a POISON CENTER or doctor/physician if you feel unwell. 如果你感觉不适,呼叫解毒中心或医生/医师。
  • P332+P313
  • P337+P313
  • P362 Take off contaminated clothing and wash before reuse. 脱掉污染的衣服,清洗后方可重新使用
Hazard statements
  • H300 Fatal if swallowed 吞食致命
  • H303 May be harmfully swallowed 吞食可能有害
  • H310 Fatal in contact with skin 皮肤接触致命
  • H330 Fatal if inhaled 吸入致命
  • H373 May causes damage to organs through prolonged or repeated exposure 长期或频繁接触可能会损伤器官
  • H411 Toxictoaquaticlifewithlonglastingeffects 对水生生物有毒性并具有长期影响。
WGK Germany3
Personal Protective Equipment dust mask type N95 (US), Eyeshields, Gloves
Signal word Danger
Safety Statements
  • S24 Avoid contact with skin 避免皮肤接触;
  • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后,立即用大量水冲洗并征求医生意见;
  • S28 After contact with skin, wash immediately with plenty of ... (to be specified by the manufacturer) 皮肤接触后,立即用大量…(由生产厂家指定)冲洗;
  • S36/37 Wear suitable protective clothing and gloves 穿戴适当的防护服和手套;
  • S37 Wear suitable gloves 戴适当手套;
  • S45 In case of accident or if you feel unwell seek medical advice immediately (show the label where possible) 发生事故时或感觉不适时,立即求医(可能时出示标签);
  • S61 Avoid release to the environment. Refer to special instructions/safety data sheet 避免释放到环境中,参考特别指示/安全收据说明书;
Risk Statements
  • R26/27/28 Very toxic by inhalation, in contact with skin and if swallowed 吸入,皮肤接触及吞食都有剧毒
  • R33 Danger of cumulative effects 有累积作用的危险
  • R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
  • R51/53
Hazard Codes 9
Packing GroupIII
Hazard Class6.1(b)
Storage condition 2-8°C, protect from light {LY} 2-8°C, protect from light {} {LY} 2-8°C, protect from light {} {} {LY} 2-8°C, protect from light {} {} {} {LY} 2-8°C, protect from light {} {} {} {} {LY} 2-8°C, protect from light {} {} {} {} {} {LY} 2-8°C, protect from light {} {} {} {} {} {} {LY} 2-8°C, protect from light {} {} {} {} {} {} {} {LY} 2-8°C, protect from light {} {} {} {} {} {} {} {} {LY} 2-8°C, protect from light {} {} {} {} {} {} {} {} {} {LY} 2-8°C, protect from light {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C, protect from light {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C, protect from light {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C, protect from light {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C, protect from light {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C, protect from light {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C, protect from light {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {}
UN Number 3077
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 80 gm/kg/78W-I
TOXIC EFFECTS :
   Tumorigenic - equivocal tumorigenic agent by RTECS criteria
   Liver - tumors
   Blood - tumors
REFERENCE :
   NTIS** National Technical Information Service.  (Springfield, VA 22161)
   Formerly U.S. Clearinghouse for Scientific & Technical Information.
   Volume(issue)/page/year: PB223-159

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 2400 mg/kg
TOXIC EFFECTS :
   Behavioral - tremor
   Behavioral - convulsions or effect on seizure threshold
   Behavioral - ataxia
REFERENCE :
   TSCAT* Office of Toxic Substances Report.  (U.S. Environmental Protection
   Agency, Office of Toxic Substances, 401 M St., SW, Washington, DC 20460)
   Volume(issue)/page/year: OTS 206512

TYPE OF TEST            : LC50 - Lethal concentration, 50 percent kill
ROUTE OF EXPOSURE       : Inhalation
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : >21600 mg/m3/1H
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   PEMNDP Pesticide Manual.  (The British Crop Protection Council, 20 Bridport
   Rd., Thornton Heath CR4 7QG, UK)  V.1-    1968-  Volume(issue)/page/year:
   9,265,1991

TYPE OF TEST            : LD50 - Let

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Administration onto the skin
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : >5 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   PEMNDP Pesticide Manual.  (The British Crop Protection Council, 20 Bridport
   Rd., Thornton Heath CR4 7QG, UK)  V.1-    1968-  Volume(issue)/page/year:
   9,265,1991

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Unreported
SPECIES OBSERVED        : Mammal - species unspecified
DOSE/DURATION           : 1500 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   30ZDA9 "Chemistry of Pesticides," Melnikov, N.N., New York, Springer-Verlag
   New York, Inc., 1971  Volume(issue)/page/year: -,87,1971

TYP

TYPE OF TEST            : Mutation in microorganisms
TEST SYSTEM             : Mold - Aspergillus nidulans
DOSE/DURATION           : 14 umol/L
REFERENCE :
   PHYTAJ Phytopathology.  (American Phytopathological Soc., 3340 Pilot Knob
   Rd., St. Paul, MN 55121) V.1-    1911-  Volume(issue)/page/year: 66,217,1976

TYPE OF TEST            : Mutation in microorganisms
TEST SYSTEM             : Bacteria - Salmonella typhimurium
DOSE/DURATION           : 100 ug/plate
REFERENCE :
   EMMUEG Environmental and Molecular Mutagenesis.  (Alan R. Liss, Inc., 41 E.
   11th St., New York, NY 10003)  V.10-    1987-  Volume(issue)/page/year:
   19(Suppl 21),2,1992

TYPE OF TEST            : Sex chromosome loss and nondisjunction
TEST SYSTEM             : Mold - Aspergillus nidulans
DOSE/DURATION           : 38 umol/L
REFERENCE :
   EVHPAZ EHP, Environmental Health Perspectives.  (U.S. Government Printing
   Office, Supt of Documents, Washington, DC 20402)  No.1-    1972-
   Volume(issue)/page/year: 31,81,1979

TYPE OF TEST            : Mutation in microorganisms
TEST SYSTEM             : Bacteria - Salmonella typhimurium
DOSE/DURATION           : 2500 ug/plate
REFERENCE :
   SAIGBL Sangyo Igaku.  Japanese Journal of Industrial Health.  (Nippon Sangyo
   Eisei Igakkai, Kosu Eisei Bldg., 1-29-8, Shinjuku, Shinjuku-ku, Tokyo 160,
   Japan)  V.1-    1959-  Volume(issue)/page/year: 29,34,1987

其他信息

  • 毒性分级:中毒
  • 用途一:用作染料及有机颜料中间体
  • MSDS 信息:氯硝胺(99-30-9).msds
  • 图谱信息:2,6-二氯-4-硝基苯胺(99-30-9)质谱(MS) 2,6-二氯-4-硝基苯胺(99-30-9)红外图谱(IR2) 2,6-二氯-4-硝基苯胺(99-30-9)红外图谱(IR1)
  • 难溶于水,易溶于乙醇,对光和热稳定,可升华
  • 海关编码:29214210
  • 灭火剂:砂土、干粉、泡沫
  • 储运特性:库房通风低温干燥; 与食品原料分开储运
  • 类别:农药
  • 急性毒性:口服-大鼠 LD50: 2400 毫克/公斤; 口服-小鼠 LD50: 1500 毫克/公斤
  • 方法一:主要有下列方法:对硝基苯胺在盐酸-冰醋酸中氯化;2-磺酸基-4-硝基苯胺氯化;对硝基苯胺在稀盐酸及次氯酸钠中氯化;对硝基苯胺在过氧化氢及盐酸中反应;对硝基苯胺在浓硫酸中先磺化再氯化;对硝基苯胺在浓盐酸中与氯酸钠反应。
  • 用途二:用作重要的染料中间体,用于分散黄棕3GL、分解黄棕2RFL、分散棕3R、分散棕5R。在50年代末期,开始作为杀菌剂商品出售。作为广谱性农用杀菌剂,可防治甘薯、洋麻、黄瓜、莴苣、棉花、烟草、草莓、马铃薯等的菌核病;甘薯、棉花及桃子的软腐病;马铃薯和西红柿的晚疫病;杏、扁桃及苹果的枯萎病;小麦的黑穗病;蚕豆花腐病。氯硝胺可与大多数杀虫剂、杀菌剂、波尔多合剂及石灰硫磺等混配使用。
  • TCI Shanghai:2,6-二氯-4-硝基苯胺 2,6-Dichloro-4-nitroaniline,>;97.0%(GC)(99-30-9)
  • 外观性质:原药为黄色针状结晶。
  • 可燃性危险特性:受热分解有毒氯化物、氧化氮气体
  • Alfa Aesar:2,6-二氯-4-硝基苯胺,95% 2,6-Dichloro-4-nitroaniline, 95%(99-30-9)
  • 2,6-二氯-4-硝基苯胺价格(试剂级):更新日期 产品编号 产品名称 包装 价格 2014/06/02 D0385 2,6-二氯-4-硝基苯胺 2,6-Dichloro-4-nitroaniline 500G 787元 2014/06/02 D0385 2,6-二氯-4-硝基苯胺 2,6-Dichloro-4-nitroaniline 25G 124元 2010/06/21 113491000 2,6-二氯-4-硝基苯胺 2,6-Dichloro-4-nitroaniline 95% 100 GR 277元
  • 上游原料:盐酸 --> 过氧化氢 --> 氯 --> 次氯酸钠 --> 4-硝基苯胺 --> 稀盐酸
  • 下游产品:3,5-二氯苯胺 --> 分散黄棕S-2RFL --> 分散橙 30 --> 分散黄棕 S-3GL --> 分散橙 76 --> 分散黄 163 --> 分散黄棕H-2RL --> 分散蓝S-BBL --> 分散棕 1 --> 分散蓝 CR-E --> 分散棕 19 --> 阳离子橙 GLH
  • Sigma Aldrich:99-30-9(sigmaaldrich)
  • Acros Organics:2,6-二氯-4-硝基苯胺 2,6-Dichloro-4-nitroaniline, 95%(99-30-9)
  • MOL 文件:99-30-9.mol

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