3,3'-Diaminobenzidine 3,3′-二氨基联苯胺

CAS 91-95-2 MFCD00007725

化学结构图

91-95-2
SMILES: Nc1ccc(-c2ccc(N)c(N)c2)cc1N

化学属性

Mol. FormulaC12H14N4
Mol. Weight214.27
Melting Point175-177°C
TSCAYes
Density1.307
Solubility0.55 g/L (20 °C)
Appearance tablet
Stability对热,光线和空气敏感
Boiling Point344.41 °C at 760 mmHg

别名和识别编码

Chemical Name3,3′-Diaminobenzidine
MDL NumberMFCD00007725
PubChem Substance ID7071
CAS Number91-95-2
Synonym DAB {LY} DAB Diaminobenzidine, 3,3 Diaminobenzidine, 3,3' {} {LY} DAB {} {} {LY} DAB {} {} {} {LY} DAB {} {} {} {} {LY} DAB {} {} {} {} {} {LY} DAB {} {} {} {} {} {} {LY} DAB {} {} {} {} {} {} {} {LY} DAB {} {} {} {} {} {} {} {} {LY} DAB {} {} {} {} {} {} {} {} {} {LY} DAB {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} DAB {} {} {} {} {} {} {} {} {} {} {} {LY} DAB {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} DAB {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} DAB {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} DAB {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} DAB {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} DAB {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} DAB {} {} {} {} {} {} {} {} {} {} {} {
Beilstein Registry Number1212988
EC Number202-110-6
Chemical Name Translation3,3′-二氨基联苯胺
Reaxys-RN1212988
Wiswesser Line NotationZR BZ DR CZ DZ
LabNetwork Molecule IDLN00221602
InChIInChI=1S/C12H14N4/c13-9-3-1-7(5-11(9)15)8-2-4-10(14)12(16)6-8/h1-6H,13-16H2
Canonical SMILESNC1=CC=C(C2=CC=C(N)C(N)=C2)C=C1N
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分类

  • {SNA} Alphabetical Listing, Blotting/Histochemistry Substrates, Colorimetric, Core Bioreagents, Detection, Detection Substrates, Enzyme Substrates, Immunohistochemistry, Life Science Reagents for Immunohistochemistry (IHC), Life Science Reagents for Western Blotting, Peroxidase, Peroxidase Substrates,

产品应用

  • 核酸染料。
  • 过氧化物酶底物;分光光度法测定硒的试剂。

相关文献及参考

  • Beilstein: 13,IV,530

安全信息

Hazard Codes T Xn O,T O,F,T
GHS Symbol
Precautionary statements
  • P201 Obtain special instructions before use. 使用前获取专门指示。
  • P202 Do not handle until all safety precautions have been read and understood. 已阅读并理解所有的安全预防措施之前,切勿操作。
  • P203
  • P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking. 远离热源/火花/明火/热的表面。——禁止吸烟。
  • P220 Keep/Store away from clothing/…/combustible materials. 保持远离/贮存远离服装/....../可燃材料。
  • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
  • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
  • P281 Use personal protective equipment as required. 使用所需的个人防护装备。
  • P301+P312+P330
  • P305+P351+P338
  • P308+P313
  • P318
  • P337+P313
  • P405 Store locked up. 上锁保管。
  • P501 Dispose of contents/container to..… 处理内容物/容器.....
Hazard statements
  • H225 Highly flammable liquid and vapour 高度易燃液体和蒸气
  • H272 May intensify fire; oxidizer 可能加剧火势;氧化剂。
  • H302 Harmful if swallowed 吞食有害
  • H314 Causes severe skin burns and eye damage 导致严重的皮肤灼伤和眼睛损伤
  • H315 Causes skin irritation 会刺激皮肤
  • H319 Causes serious eye irritation 严重刺激眼睛
  • H335 May cause respiratory irritation 可能导致呼吸道刺激
  • H335+H336
  • H341 Suspected of causing genetic defects 怀疑导致遗传性缺陷
  • H350 May cause cancer 可能致癌
Signal word Danger
WGK Germany1
RTECSDV8750000
Personal Protective Equipment dust mask type N95 (US), Eyeshields, Gloves
Safety Statements
  • S45 In case of accident or if you feel unwell seek medical advice immediately (show the label where possible) 发生事故时或感觉不适时,立即求医(可能时出示标签);
  • S53 Avoid exposure - obtain special instructions before use 避免接触,使用前获得特别指示说明;
Risk Statements
  • R45 May cause cancer 可能致癌
  • R68 Possible risk of irreversible effects 可能有不可挽回的作用的危险
Storage condition 2-8°C, protect from light {LY} 2-8°C, protect from light Light Sensitive {} {LY} 2-8°C, protect from light {} {} {LY} 2-8°C, protect from light {} {} {} {LY} 2-8°C, protect from light {} {} {} {} {LY} 2-8°C, protect from light {} {} {} {} {} {LY} 2-8°C, protect from light {} {} {} {} {} {} {LY} 2-8°C, protect from light {} {} {} {} {} {} {} {LY} 2-8°C, protect from light {} {} {} {} {} {} {} {} {LY} 2-8°C, protect from light {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C, protect from light {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C, protect from light {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C, protect from light {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C, protect from light {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C, protect from light {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C, protect from light {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C, protect from light {} {} {} {} {} {} {} {} {} {} {} {} {} {} {
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 9000 mg/kg/27D-I
TOXIC EFFECTS :
   Tumorigenic - equivocal tumorigenic agent by RTECS criteria
   Skin and Appendages - tumors
REFERENCE :
   CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut
   Sts., Philadelphia, PA 19106)  V.1-    1941-  Volume(issue)/page/year:
   28,924,1968

TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 3 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut
   Sts., Philadelphia, PA 19106)  V.1-    1941-  Volume(issue)/page/year:
   26,619,1966

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 1834 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   GISAAA Gigiena i Sanitariya.  For English translation, see HYSAAV.  (V/O
   Mezhdunarodnaya Kniga, 113095 Moscow, USSR)  V.1-    1936-
   Volume(issue)/page/year: 46(1),94,1981

TYPE OF TEST            : Unscheduled DNA synthesis
TEST SYSTEM             : Rodent - rat Liver
DOSE/DURATION           : 500 umol/L
REFERENCE :
   ENMUDM Environmental Mutagenesis.  (New York, NY)  V.1-9, 1979-87.  For
   publisher information, see EMMUEG.  Volume(issue)/page/year: 3,11,1981

TYPE OF TEST            : Cytogenetic analysis
ROUTE OF EXPOSURE       : Intraperitoneal
TEST SYSTEM             : Rodent - mouse
DOSE/DURATION           : 100 mg/kg
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.

TYPE OF TEST            : Mutation in microorganisms
TEST SYSTEM             : Bacteria - Salmonella typhimurium
DOSE/DURATION           : 25 ug/plate
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 158,19,1985

TYPE OF TEST            : Mutation in microorganisms
TEST SYSTEM             : Yeast - Saccharomyces cerevisiae
DOSE/DURATION           : 140 umol/L
REFERENCE :
   MGGEAE Molecular and General Genetics.  (Springer-Verlag, Heidelberger Pl.
   3, D-1000 Berlin 33, Fed. Rep. Ger.)  V.99-    1967-
   Volume(issue)/page/year: 174,39,1979

TYPE OF TEST            : DNA adduct
TEST SYSTEM             : Bacteria - Escherichia coli
DOSE/DURATION           : 20 umol/L
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 89,95,1981

TYPE OF TEST            : Mutation test systems - not otherwise specified
ROUTE OF EXPOSURE       : Intraperitoneal
TEST SYSTEM             : Rodent - mouse
DOSE/DURATION           : 100 mg/kg
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 319,19,1993

其他信息

  • 用途二:光度法测定硒,过氧化物酶底物。
  • Sigma Aldrich:91-95-2(sigmaaldrich)
  • 上游原料:联苯胺
  • 可燃性危险特性:可燃; 燃烧产生有毒氮氧化物烟雾
  • 储运特性:库房通风低温干燥
  • Acros Organics:3,3'-二氨基联苯胺 3,3'-Diaminobenzidine, 99%(91-95-2)
  • 3,3'-二氨基联苯胺价格(试剂级):更新日期 产品编号 产品名称 包装 价格 2014/06/02 D0077 3,3'-二氨基联苯胺 3,3'-Diaminobenzidine 5G 489元 2014/06/02 D0077 3,3'-二氨基联苯胺 3,3'-Diaminobenzidine 25G 1500元 2014/06/02 D3756 3,3'-二氨基联苯胺[用于生化研究] 3,3'-Diaminobenzidine [for Biochemical Research] 1G 218元
  • 毒性分级:中毒
  • 急性毒性:口服-大鼠 LDL0: 3000 毫克/公斤; 口服-小鼠 LD50: 1834 毫克/公斤
  • 用途一:用作耐高温聚合物的单体
  • MOL 文件:91-95-2.mol
  • 图谱信息:3,3'-二氨基联苯胺(91-95-2)红外图谱(IR1) 3,3'-二氨基联苯胺(91-95-2)核磁图( 1 HNMR) 3,3'-二氨基联苯胺(91-95-2)红外图谱(IR2) 3,3'-二氨基联苯胺(91-95-2)质谱(MS) 3,3'-二氨基联苯胺(91-95-2)核磁图( 13 CNMR)
  • F:8-10-23
  • TCI Shanghai:3,3'-二氨基联苯胺[用于生化研究] 3,3'-Diaminobenzidine [for Biochemical Research],>;98.0%(T)(91-95-2)
  • 灭火剂:干粉,泡沫,沙土,二氧化碳, 雾状水
  • 类别:有毒物品

系列性分类


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