5-Chloro-2-methylaniline 5-氯-2-甲基苯胺

CAS 95-79-4 MFCD00007779

化学结构图

95-79-4
SMILES: Cc1ccc(Cl)cc1N

化学属性

Mol. FormulaC7H8ClN
Mol. Weight141.60
Density1.177
Refractive index1.58
Flash Point160°(320°F)
TSCAYes
Boiling Point237
Melting Point20-22
Solubility< 1 G/L (22 ºC)

别名和识别编码

Chemical Name5-Chloro-2-methylaniline
CAS Number95-79-4
EC Number202-452-6
Beilstein Registry Number878504
MDL NumberMFCD00007779
Synonym 5-Chloro-2-methylaniline {LY} 5-Chloro-2-methylaniline 5-Chloro-o-toluidine 5-Chloro-o-toluidine; 2-Amino-4-chlorotoluene; C.I. 37090 5-氯-2-甲基苯胺 5-氯邻甲苯胺 AKOS BBS-00003551 Acco Fast Red KB Base Azoene Fast Red KB Base Azoic Diazo Component 32 Benzenamine, 5-chloro-2-methyl- Fast Red KB Salt Fast Red KB Salt Supra Fast Red KB base Fast Red KBS Salt Genazo Red KB Soln NCI-C02051 Stable Red KB Base {} {LY} 5-Chloro-2-methylaniline {} {} {LY} 5-Chloro-2-methylaniline {} {} {} {LY} 5-Chloro-2-methylaniline {} {} {} {} {LY} 5-Chloro-2-methylaniline {} {} {} {} {} {LY} 5-Chloro-2-methylaniline {} {} {} {} {} {} {LY} 5-Chloro-2-methylaniline {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 5-Chloro-2-methylaniline {} {} {} {} {} {} {} {} {} {} {} {} {} {
PubChem Substance ID87559367
Reaxys-RN878504
Chemical Name Translation5-氯-2-甲基苯胺
Wiswesser Line NotationZR CG F1
InChIInChI=1S/C7H8ClN/c1-5-2-3-6(8)4-7(5)9/h2-4H,9H2,1H3
LabNetwork Molecule IDLN00010136
Canonical SMILESNC1=CC(Cl)=CC=C1C
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产品应用

  • 用于有机合成。染料行业中可直接用其合成冰染染料红色基KB、色酚AS-KB,它还是一种重要的农药中间体。

相关文献及参考

  • Beilstein:12(4)1794

安全信息

Signal word Warning
GHS Symbol
WGK Germany3
Safety Statements
  • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后,立即用大量水冲洗并征求医生意见;
  • S36/37/39 Wear suitable protective clothing, gloves and eye/face protection 穿戴适当的防护服、手套和眼睛/面保护;
  • S45 In case of accident or if you feel unwell seek medical advice immediately (show the label where possible) 发生事故时或感觉不适时,立即求医(可能时出示标签);
Risk Statements
  • R22 Harmful if swallowed 吞咽有害
  • R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
  • R40 Limited evidence of a carcinogenic effect 有限证据表明其致癌作用
Precautionary statements
  • P260 Do not breathe dust/fume/gas/mist/vapours/spray. 不要吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
  • P270 Do not eat, drink or smoke when using this product. 使用本产品时不要吃东西,喝水或吸烟。
  • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
  • P301+P312+P330
  • P302+P352+P332+P313+P362+P364
  • P305+P351+P338
  • P305+P351+P338+P337+P313
  • P308+P311
  • P332+P313
  • P362 Take off contaminated clothing and wash before reuse. 脱掉污染的衣服,清洗后方可重新使用
  • P405 Store locked up. 上锁保管。
  • P501 Dispose of contents/container to..… 处理内容物/容器.....
RTECSXU5075000
Packing GroupIII
UN Number 2239 3429
Hazard statements
  • H302 Harmful if swallowed 吞食有害
  • H315 Causes skin irritation 会刺激皮肤
  • H319 Causes serious eye irritation 严重刺激眼睛
  • H335 May cause respiratory irritation 可能导致呼吸道刺激
Personal Protective Equipment dust mask type N95 (US), Eyeshields, Faceshields, Gloves
Hazard Codes 6.1 Xn
Hazard Class6.1
Warnings 危化品目录(2015)
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 164 gm/kg/78W-C
TOXIC EFFECTS :
   Tumorigenic - equivocal tumorigenic agent by RTECS criteria
   Endocrine - adrenal cortex tumors
REFERENCE :
   NCITR* National Cancer Institute Carcinogenesis Technical Report Series.
   (Bethesda, MD)  No.0-205. For publisher information, see NTPTR*.
   Volume(issue)/page/year: NCI-TR-187,1979

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 131 gm/kg/78W-C
TOXIC EFFECTS :
   Tumorigenic - Carcinogenic by RTECS criteria
   Vascular - tumors
   Liver - tumors
REFERENCE :
   NCITR* National Cancer Institute Carcinogenesis Technical Report Series.
   (Bethesda, MD)  No.0-205. For publisher information, see NTPTR*.
   Volume(issue)/page/year: NCI-TR-187,1979

TYPE OF TEST            : TD - Toxic dose (other than lowest)
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 262 gm/kg/78W-C
TOXIC EFFECTS :
   Tumorigenic - Carcinogenic by RTECS criteria
   Vascular - tumors
   Liver - tumors
REFERENCE :
   NCITR* National Cancer Institute Carcinogenesis Technical Report Series.
   (Bethesda, MD)  No.0-205. For publisher information, see NTPTR*.
   Volume(issue)/page/year: NCI-TR-187,1979

TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Mammal - dog
DOSE/DURATION           : >100 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   28ZEAL "Pesticide Index," Frear, E.H., ed., State College, PA, College
   Science Pub., 1969  Volume(issue)/page/year: 4,113,1969

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 464 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   NCILB* Progress Report for Contract No. NIH-NCI-E-C-72-3252, Submitted to
   the National Cancer Institute by Litton Bionetics, Inc.  (Bethesda, MD)
   Volume(issue)/page/year: NCI-E-C-72-3252,1973

TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Mammal - domestic
DOSE/DURATION           : >200 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   28ZEAL "Pesticide Index," Frear, E.H., ed., State College, PA, College
   Science Pub., 1969  Volume(issue)/page/year: 4,113,1969

TYPE OF TEST            : Mutation test systems - not otherwise specified
ROUTE OF EXPOSURE       : Oral
TEST SYSTEM             : Rodent - mouse
DOSE/DURATION           : 50 mg/kg
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 343,157,1995

TYPE OF TEST            : DNA inhibition
ROUTE OF EXPOSURE       : Oral
TEST SYSTEM             : Rodent - mouse
DOSE/DURATION           : 200 mg/kg
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 46,305,1977

Restrict 危险品
Storage condition Store at room temperature {LY} Store at room temperature {} {LY} Store at room temperature {} {} {LY} Store at room temperature {} {} {} {LY} Store at room temperature {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {}

其他信息

  • Sigma Aldrich:95-79-4(sigmaaldrich)
  • 5-氯邻甲苯胺价格(试剂级):更新日期 产品编号 产品名称 包装 价格 2011/04/16 C1876 2-氨基-4-氯甲苯 5-Chloro-2-methylaniline 25G 162元 2011/04/16 C1876 2-氨基-4-氯甲苯 5-Chloro-2-methylaniline 500G 1320元 2010/06/21 109381000 5-氯邻甲苯胺 5-Chloro-2-methylaniline 98% 100 GR 340元
  • 急性毒性:口服- 大鼠 LD50: 464 毫克/ 公斤
  • Acros Organics:5-氯-2-甲基苯胺 5-Chloro-2-methylaniline, 98%(95-79-4)
  • MSDS 信息:5-氯-2-甲基苯胺(95-79-4).msds
  • 类别:有毒物品
  • 有刺激性气味,溶于热乙醇。
  • Alfa Aesar:5-氯-2-甲基苯胺,99% 5-Chloro-2-methylaniline, 99%(95-79-4)
  • 用途一:染料行业中可直接用其合成冰染染料红色基KB、色酚AS-KB,它还是一种重要的农药中间体
  • 用途三:用于有机合成。染料行业中可直接用其合成冰染染料红色基KB、色酚AS-KB,它还是一种重要的农药中间体。
  • TCI Shanghai:5-氯-2-甲基苯胺 2-Amino-4-chlorotoluene,>;98.0%(GC)(T)(95-79-4)
  • 用途二:用作棉、丝及锦纶织物染色和印花的显色剂,用于制造快色素
  • 图谱信息:5-氯邻甲苯胺(95-79-4)红外图谱(IR2) 5-氯邻甲苯胺(95-79-4)核磁图( 1 HNMR) 5-氯邻甲苯胺(95-79-4)质谱(MS) 5-氯邻甲苯胺(95-79-4)红外图谱(IR1) 5-氯邻甲苯胺(95-79-4)核磁图( 13 CNMR)
  • 下游产品:2,4-二氯甲苯 --> 显色基艳红 B
  • 可燃性危险特性:明火可燃; 高热放出有毒的氯化物及氮氧化物气体
  • 海关编码:29214300
  • 储运特性:库房通风低温干燥; 与氧化剂、食品添加剂分开存放
  • 上游原料:铁粉 --> 2-硝基甲苯
  • 毒性分级:高毒
  • 外观性质:棕褐色片状结晶,有刺激性气味。
  • 灭火剂:雾状水、泡沫、二氧化碳、砂土
  • MOL 文件:95-79-4.mol
  • 5-氯邻甲苯胺价格(试剂级):更新日期 产品编号 产品名称 包装 价格 2014/06/02 C1876 2-氨基-4-氯甲苯 5-Chloro-2-methylaniline 25G 163元 2014/06/02 C1876 2-氨基-4-氯甲苯 5-Chloro-2-methylaniline 500G 1310元 2010/06/21 109381000 5-氯邻甲苯胺 5-Chloro-2-methylaniline 98% 100 GR 340元

系列性分类


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