3-Ethoxyaniline 间氨基苯乙醚

CAS 621-33-0 MFCD00007785

化学结构图

621-33-0
SMILES: CCOc1cccc(N)c1

化学属性

Mol. FormulaC₈H₁₁NO
Mol. Weight137.18
Refractive indexn20/D 1.566(lit.)
Boiling Point-
Density1.032
Flash Point-
Melting Point1 ºC
Solubility<0.1 G/100 ML AT 19 ºC
Appearance 无色油状液体。沸点248℃，167-169℃（12.93kPa），127-128℃（1.47kPa），相对密度1.032，折光率1.5655。溶于醇和醚，微溶于水，遇光和空气变成棕黄色。

别名和识别编码

Chemical Name3-Ethoxyaniline
Synonym 1-Amino-3-methoxybenzene 3'-AMINOPHENETOL 3-Aminoanisole 3-Aminoanisole; 3-Methoxyaniline 3-Aminoethoxybenzene 3-ETHOXYANILINE 3-ETHOXYANILINE / M-PHENETIDINE 3-ETHOXYBENZENAMINE 3-Ethoxyaniline 3-Phenetidine {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {}
MDL Number-
CAS Number621-33-0
PubChem Substance ID12120
EC Number210-680-2
Beilstein Registry Number971028
Chemical Name Translation间氨基苯乙醚
LabNetwork Molecule IDLN00226543
InChIInChI=1S/C8H11NO/c1-2-10-8-5-3-4-7(9)6-8/h3-6H,2,9H2,1H3
Canonical SMILES-
信息真实价格透明    资金保障    专业采购外包团队在线服务   
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品牌质保精细包装    现货库存    一流品牌服务   

分类

  • {uni_hamburg} no charge; carbocycle; aromatic; 6RingOnly; 6ring; ether; 1fragment
  • {SNA} Amines, Building Blocks, C8, Chemical Synthesis, Nitrogen Compounds, Organic Building Blocks

相关文献及参考

  • Short: II/27B
  • Beilstein: 13,IV,954
  • Short: III/20a

安全信息

GHS Symbol
WGK Germany3
Hazard statements
  • H331 Toxic if inhaled 吸入中毒
  • H311 Toxic in contact with skin 皮肤接触中毒
  • H301 Toxic if swallowed 吞食有毒
  • H373 May causes damage to organs through prolonged or repeated exposure 长期或频繁接触可能会损伤器官
  • H301+H311+H331
Personal Protective Equipment Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter
RTECSSI5400000
Precautionary statements
Signal word
Hazard Codes T
Safety Statements
  • S36/37/39 Wear suitable protective clothing, gloves and eye/face protection 穿戴适当的防护服、手套和眼睛/面保护；
  • S28 After contact with skin, wash immediately with plenty of ... (to be specified by the manufacturer) 皮肤接触后，立即用大量…（由生产厂家指定）冲洗；
  • S36/37 Wear suitable protective clothing and gloves 穿戴适当的防护服和手套；
  • S45 In case of accident or if you feel unwell seek medical advice immediately (show the label where possible) 发生事故时或感觉不适时，立即求医（可能时出示标签）；
  • S61 Avoid release to the environment. Refer to special instructions/safety data sheet 避免释放到环境中，参考特别指示/安全收据说明书；
Risk Statements
  • R33 Danger of cumulative effects 有累积作用的危险
  • R23/24/25 Toxic by inhalation, in contact with skin and if swallowed 吸入，皮肤接触及吞食都有毒
  • R26/27/28 Very toxic by inhalation, in contact with skin and if swallowed 吸入，皮肤接触及吞食都有剧毒
  • R51/53
UN Number
Packing GroupIII
Hazard Class6.1(b)
Warnings 危化品目录(2015) 
TYPE OF TEST            : Mutation in microorganisms
TEST SYSTEM             : Bacteria - Salmonella typhimurium
DOSE/DURATION           : 1 mg/plate
REFERENCE :
   EMMUEG Environmental and Molecular Mutagenesis.  (Alan R. Liss, Inc., 41 E.
   11th St., New York, NY 10003)  V.10-    1987-  Volume(issue)/page/year:
   11(Suppl 12),1,1988

Restrict 危险品
Storage condition 4°C 4°C, Inert atmosphere

其他信息

  • MOL 文件:621-33-0.mol
  • 储运特性:库房通风低温干燥; 与食品原料分开储运
  • 方法一:由间氨基酚经乙酰化、烷基化、水解、中和而得。1.乙酰化将间氨基酚加入乙酸中，加热回流8h。回收乙酸后，水析，冷后过滤即得乙酰氨基酚（[621-42-1]）。2.烷基化将乙醇、氢氧化钠、间乙酰氨基酚、溴乙烷加入反应器中，加热回流8h，倒入水中冷却过滤，得间乙酰氨基苯乙醚。3.水解、中和将间乙酰氨基苯乙醚与工业盐酸混合，于水浴加热8h，然后倒入水中，用40%氢氧化钠中和至碱性。分出油层。水溶液用乙醚提取，回收乙醚后与油层一起减压蒸馏，在氮气保护下收集140-144℃（2.0kPa）馏分，即为间乙氧基苯胺。
  • 用途一:用于有机合成。
  • 间氨基苯乙醚价格(试剂级):更新日期 产品编号 产品名称 包装 价格 2010/06/21 186720250 间氨基苯乙醚 m-Phenetidine 98% 25 ML 1986元 2010/06/21 186720050 间氨基苯乙醚 m-Phenetidine 98% 5 ML 578元
  • 毒性分级:中毒
  • 海关编码:29222200
  • 灭火剂:雾状水、二氧化碳、砂土、干粉
  • 上游原料:溴乙烷 --> 3-氨基苯酚 --> 工业盐酸 --> N-乙酰苯胺 --> 苯乙醚 --> 乙酰氨基酚 --> N-(3-羟基苯基)乙酰胺
  • Sigma Aldrich:621-33-0(sigmaaldrich)
  • Acros Organics:间氨基苯乙醚 m-Phenetidine, 98%(621-33-0)
  • F:8-10-23
  • 可燃性危险特性:明火可燃; 受热放出有毒苯胺类气体
  • MSDS 信息:3-Ethoxybenzenamine(621-33-0).msds
  • 图谱信息:间氨基苯乙醚(621-33-0)红外图谱(IR1) 间氨基苯乙醚(621-33-0)核磁图( 13 CNMR) 间氨基苯乙醚(621-33-0)核磁图( 1 HNMR) 间氨基苯乙醚(621-33-0)质谱(MS)
  • 类别:有毒物品

系列性分类

  1. C12 - Amines
  1. C8 - Amines
  1. Chemical Synthesis 化学合成
  2. Building Blocks 合成砌块
  3. Organic Building Blocks 有机砌块
  4. Nitrogen Compounds 氮化合物
  5. Amines 胺
  6. C7