• 原料直供
• 试剂商城
• 直接询价

分类

• {SNA} Cell Lysis and Protein Extraction Reagents, Chemical Modification Reagents, Protein Modification, Reagents for cysteine modification, Specific Amino Acid Modification, 分子生物学, 天然蛋白质样品制备, 蛋白质组学, 蛋白质结构分析
• {SNA} Cell Lysis and Protein Extraction Reagents, Chemical Modification Reagents, Native Protein Sample P

产品应用

• 在蛋白组学中组氨酸和半胱氨酸的烷基化试剂，用于多肽测序以及酶抑制剂。也用于有机合成。

相关文献及参考

• 1. Gomi, T., and Fujioka, M., Inactivation of rat liver S-adenosylhomocysteinase by iodoacetamide Biochemistry 21 , 4171-4176, (1982) 摘要
• 2. Takahashi, K., The structure and function of ribonuclease T1. XXI. Modification of histidine residues in ribonuclease T1 with iodoacetamide J. Biochem. 80 , 1267-1275, (1976) 摘要
• Snider, J., et al., Formation of a Distinctive Complex between the Inducible Bacterial Lysine Decarboxylase and a Novel AAA+ ATPase J. Biol. Chem. 281 , 1532-46, (2006) 摘要
• Beil. 2 ,IV,536
• Aldrich MSDS 1 , 1089:C / Corp MSDS 1 (1), 1990:B / FT-IR 2 (1), 1259:C / FT-IR 1 (1), 751:B / IR-Spectra (2), 389:B / IR-Spectra (3), 439:C / NMR-Reference 2 (1), 632:C / RegBook 1 (1), 879:D / Sax 6 , 1617 / Sigma FT-IR 1 (2), 656:D / Structure Index 1 , 134:B:5
• Short: II/25B Title: Structure Data Of Free Polyatomic Molecules: Molecules containing One or Two Carbon Atoms Author: Graner, G.; Hirota, E.; Iijima, T.; Kuchitsu, K.; Ramsay, D.A.; Vogt, J.; Vogt, N. Editor: Kuchitsu, K. Source: Landolt-Börnstein, New Series Volume: II/25B Year: 1999 Keyword: Free Polyatomic Molecules; Carbon Atoms; Molecules ISBN: 3-540-63645-5 ISBN: 978-3-540-63645-8 Internet Resource: DOI:10.1007/b68834 RefComment: IX, 512 pages. Hardcover Abstract: Volume II/25 is a supplemented and revised edition of the preceding volumes II/7, II/15, II/21 and II/23 containing up to date information on inorganic and organic polyatomic molecules. All experimental methods for the determination of quantitative structural data of free molecules have been considered: microwave, infrared, Raman, electronic and photoelectron spectroscopy as well as electron diffraction. The data obtained by these methods have been critically evaluated and compiled. They are presented separately for each molecule, together with a schematic figure of the structure

安全信息

GHS Symbol

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Administration onto the skin
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 1480 mg/kg/20W-I
TOXIC EFFECTS :
   Tumorigenic - equivocal tumorigenic agent by RTECS criteria
   Skin and Appendages - tumors
   Tumorigenic - tumors at site of application
REFERENCE :
   BJCAAI British Journal of Cancer.  (Macmillan Press Ltd., Houndmills,
   Basingstoke, Hants. RG21 2XS, UK)  V.1-    1947-  Volume(issue)/page/year:
   7,482,1953

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 74 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   ARTODN Archives of Toxicology.  (Springer-Verlag, Heidelberger Pl. 3, D-1000
   Berlin 33, Fed. Rep. Ger.)  V.32-    1974-  Volume(issue)/page/year:
   47,179,1981

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 50 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   NTIS** National Technical Information Service.  (Springfield, VA 22161)
   Formerly U.S. Clearinghouse for Scientific & Technical Information.
   Volume(issue)/page/year: AD277-689

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 56 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   CSLNX* U.S. Army Armament Research & Development Command, Chemical Systems
   Laboratory, NIOSH Exchange Chemicals.  (Aberdeen Proving Ground, MD 21010)
   Volume(issue)/page/year: NX#02060

TYPE OF TEST            : DNA inhibition
TEST SYSTEM             : Human Lymphocyte
DOSE/DURATION           : 10 umol/L
REFERENCE :
   STBIBN Studia Biophysica.  (Akademie-Verlag GmbH, Postfach 1233, Berlin
   DDR-1086, Ger. Dem. Rep.) V.1-    1966-  Volume(issue)/page/year: 50,97,1975

TYPE OF TEST            : DNA damage
TEST SYSTEM             : Bacteria - Escherichia coli
DOSE/DURATION           : 20 ppm
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 24,365,1974

其他信息

• F:8-10-21
• 方法一:由氯乙酰胺与碘化钠反应而得。将氯乙酰胺、无水丙酮、无水碘化钠在浴上回流15h。冷至室温，滤出氯化钠，回收丙酮，稍冷后倒入硫酸氢钠的冰水中，然后用硫酸钠饱和溶液中和至pH6。冷却结晶，过滤得粗品。粗品用水重结晶，即得成品。
• 用途一:用于有机合成
• Acros Organics:碘乙酰胺 Iodoacetamide, 98%(144-48-9)
• 用途二:在蛋白组学中组氨酸和半胱氨酸的烷基化试剂，用于多肽测序以及酶抑制剂。也用于有机合成。
• 海关编码:29241900
• MSDS 信息:2-Iodoacetamide(144-48-9).msds
• TCI Shanghai:2-碘乙酰胺 2-Iodoacetamide,>;98.0%(T)(144-48-9)
• MOL 文件:144-48-9.mol
• Sigma Aldrich:144-48-9(sigmaaldrich)
• 溶于热水，易溶于乙醇。
• 图谱信息:2-碘乙酰胺(144-48-9)核磁图( 13 CNMR) 2-碘乙酰胺(144-48-9)红外图谱(IR2) 2-碘乙酰胺(144-48-9)核磁图( 1 HNMR) 2-碘乙酰胺(144-48-9)红外图谱(IR1) 2-碘乙酰胺(144-48-9)质谱(MS)
• 2-碘乙酰胺价格(试剂级):更新日期 产品编号 产品名称 包装 价格 2011/08/23 LA1471502 碘代乙酰胺 25g 719元 2011/08/23 K5767001 碘代乙酰胺（+4℃） 25g 1650元 2011/04/16 I0741 2-碘乙酰胺[用于生化研究] 2-Iodoacetamide [for Biochemical Research] 5G 509元
• 上游原料:丙酮 --> 碘化钠 --> 氯乙酰胺 --> 无水丙酮
• TSCA:T
• Alfa Aesar:2-碘乙酰胺,98%,stab.withca5-8%water 2-Iodoacetamide, 98%, stab. with ca 5-8% water(144-48-9)
• 敏感性:Light Sensitive