CAS 1609-47-8 MFCD00009106-Diethyl Pyrocarbonate 焦碳酸二乙酯 -LabNovo

Diethyl Pyrocarbonate 焦碳酸二乙酯

CAS 1609-47-8 MFCD00009106

化学结构图

SMILES: CCOC(=O)OC(=O)OCC

化学属性

Mol. Formula	C6H10O5
Mol. Weight	162.14
Refractive index	n20/D 1.398(lit.)
Boiling Point	93-94°C at 18 mmHg
Density	1.101
Flash Point	69°(156°F)
TSCA	Yes
Solubility	Soluble in chloroform, ethanol (50% w/w), esters, ketones, and hydrocarbons.Slowly soluble in water with hydrolytic decomposition yielding ethanol and CO2.
Stability	对湿度敏感
Appearance	无色透明液体, 密度 1.101,沸点 93-94 ℃ , 折射率 1.396-1.4 ,闪点 69 ℃
Melting Point	<25 °C

别名和识别编码

Chemical Name	Diethyl pyrocarbonate
Synonym	Diethyl pyrocarbonate {LY} Diethyl pyrocarbonate Diethylpyrocarbonate Ethoxyformic Anhydride Oxydiformate, Diethyl Pyrocarbonate, Diethyl Pyrocarbonic Acid Diethyl Ester {} {LY} Diethyl pyrocarbonate {} {} {LY} Diethyl pyrocarbonate {} {} {} {LY} Diethyl pyrocarbonate {} {} {} {} {LY} Diethyl pyrocarbonate {} {} {} {} {} {LY} Diethyl pyrocarbonate {} {} {} {} {} {} {LY} Diethyl pyrocarbonate {} {} {} {} {} {} {} {LY} Diethyl pyrocarbonate {} {} {} {} {} {} {} {} {LY} Diethyl pyrocarbonate {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Diethyl pyrocarbonate {} {} {} {} {} {} {} {} {} {} {PubChem} Diethyl Pyrocarbonate {} {} {} {} {} {} {} {} {} {} {} {PubChem} Diethyl Oxydiformate {} {} {} {} {} {} {} {} {} {} {} {} {PubChem} Diethyl Dicarbonate {} {} {} {} {} {} {} {} {} {} {} {} {} {PubChem} Dicarbonate, Diethyl {} {} {} {} {} {} {} {} {} {} {} {} {} {}
CAS Number	1609-47-8
PubChem Substance ID	3051
EC Number	216-542-8
Beilstein Registry Number	637031
MDL Number	MFCD00009106
Merck Number	14,7998
Chemical Name Translation	焦碳酸二乙酯
Wiswesser Line Notation	2OVOVO2
LabNetwork Molecule ID	LN00193064
InChI	InChI=1S/C6H10O5/c1-3-9-5(7)11-6(8)10-4-2/h3-4H2,1-2H3
Canonical SMILES	CCOC(OC(OCC)=O)=O

信息真实价格透明资金保障专业采购外包团队在线服务

品牌质保精细包装现货库存一流品牌服务

产品应用

蛋白质组氨酸和酪氨酸的修饰试剂。也是RNA酶的化学修饰剂,它和RNA酶的活性基团组氨酸的咪唑环反应而抑制RNA酶活性。

安全信息

GHS Symbol

WGK Germany3

Hazard statements

H302 Harmful if swallowed 吞食有害
H315 Causes skin irritation 会刺激皮肤
H319 Causes serious eye irritation 严重刺激眼睛
H332 Harmful if inhaled 吸入有害
H335 May cause respiratory irritation 可能导致呼吸道刺激

Personal Protective Equipment Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter

Hazard Codes Xn

RTECSLQ9350000

Precautionary statements

P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
P264+P265
P270 Do not eat, drink or smoke when using this product. 使用本产品时不要吃东西，喝水或吸烟。
P271 Use only outdoors or in a well-ventilated area.? 只能在室外或通风良好的地方使用。
P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
P301+P312
P301+P312+P330
P301+P317
P302+P352
P304+P312
P304+P340
P305+P351+P338
P312 Call a POISON CENTER or doctor/physician if you feel unwell. 如果你感觉不适，呼叫解毒中心或医生/医师。
P319
P321 Specific treatment (see … on this label). 具体治疗（见本标签上的）。
P330 Rinse mouth. 漱口
P332+P313
P332+P317
P337+P313
P337+P317
P362 Take off contaminated clothing and wash before reuse. 脱掉污染的衣服，清洗后方可重新使用
P362+P364
P403+P233
P405 Store locked up. 上锁保管。
P501 Dispose of contents/container to..… 处理内容物/容器.....

Signal word Warning

Risk Statements

R22 Harmful if swallowed 吞咽有害
R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性

Safety Statements

S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后，立即用大量水冲洗并征求医生意见；
S36 Wear suitable protective clothing 穿戴适当的防护服；

Storage condition -20°C {LY} -20°C 2-8°C Moisture Sensitive {} {LY} -20°C {} {} {LY} -20°C {} {} {} {LY} -20°C {} {} {} {} {LY} -20°C {} {} {} {} {} {LY} -20°C {} {} {} {} {} {} {LY} -20°C {} {} {} {} {} {} {} {LY} -20°C {} {} {} {} {} {} {} {} {LY} -20°C {} {} {} {} {} {} {} {} {} {LY} -20°C {} {} {} {} {} {} {} {} {} {} {LY} -20°C {} {} {} {} {} {} {} {} {} {} {} {LY} -20°C {} {} {} {} {} {} {} {} {} {} {} {} {LY} -20°C {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} -20°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} -20°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} -20°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} -20°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} -20°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} -20°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} -20°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} -20°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {}

Packing GroupIII

Hazard Class6.1(b)

UN Number 2810

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 1558 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   FAONAU FAO Nutrition Meetings Report Series.  (Rome, Italy)  No.?-57,
   1948-77.  Discontinued.  Volume(issue)/page/year: 53A,52,1974

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 47 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   FAONAU FAO Nutrition Meetings Report Series.  (Rome, Italy)  No.?-57,
   1948-77.  Discontinued.  Volume(issue)/page/year: 53A,52,1974

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 850 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   FAONAU FAO Nutrition Meetings Report Series.  (Rome, Italy)  No.?-57,
   1948-77.  Discontinued.  Volume(issue)/page/year: 51A,67,1972

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Mammal - cat
DOSE/DURATION           : 100 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   FAONAU FAO Nutrition Meetings Report Series.  (Rome, Italy)  No.?-57,
   1948-77.  Discontinued.  Volume(issue)/page/year: 53A,52,1974

TYPE OF TEST            : LCLo - Lowest published lethal concentration
ROUTE OF EXPOSURE       : Inhalation
SPECIES OBSERVED        : Rodent - guinea pig
DOSE/DURATION           : 10 ppm/1H
TOXIC EFFECTS :
   Lungs, Thorax, or Respiration - dyspnea
REFERENCE :

其他信息

Diethyl Pyrocarbonate has been shown to inhibit ryanodine binding to ryanodine/Ca2+ receptor channels in skeletal muscle in a dose- and time-dependent manner and increases the Ca2+ permeability of SR vesicles. This compound could be useful for specific inactivation of nucleases during isolation of undegraded polynucleotides. Diethyl Pyrocarbonate also inhibits PAF Acetylhydrolase (platelet-activating factor acetyl hydrolase), and has been used as a probe for the topography of 5.8S rRNA in yeast ribosomes.
存储注意事项:氮气保护;湿度敏感
有轻微的似果酯香味。难溶于水，遇水分散成CO2及乙醇。与乙醇可混溶。溶于有机溶剂及油脂。
Acros Organics:焦碳酸二乙酯 Diethyl pyrocarbonate, pure, 97%(1609-47-8)
F:4.4-9-21
MSDS 信息:Pyrocarbonic acid diethyl ester(1609-47-8).msds
焦碳酸二乙酯价格(试剂级):更新日期产品编号产品名称包装价格 2011/08/23 L1152602 二碳酸二乙酯95％ 25g 790元 2011/08/23 30061486 焦碳酸二乙酯（+4℃） 25ml 865元 2010/06/21 170255000 焦碳酸二乙酯 Diethyl pyrocarbonate 97%, pure 500 GR 10138元
图谱信息:焦碳酸二乙酯(1609-47-8)质谱(MS) 焦碳酸二乙酯(1609-47-8)核磁图( 13 CNMR) 焦碳酸二乙酯(1609-47-8)红外图谱(IR1)
用途一:蛋白质组氨酸和酪氨酸的修饰试剂。也是RNA酶的化学修饰剂,它和RNA酶的活性基团组氨酸的咪唑环反应而抑制RNA酶活性。
MOL 文件:1609-47-8.mol
海关编码:29209085
检测方法:NMR
敏感性:Moisture Sensitive
Sigma Aldrich:1609-47-8(sigmaaldrich)
Alfa Aesar:重碳酸二乙酯,97% Diethyl dicarbonate, 97%(1609-47-8)

Diethyl Pyrocarbonate 焦碳酸二乙酯

CAS 1609-47-8 MFCD00009106

化学结构图

化学属性

别名和识别编码

分类

产品应用

相关文献及参考

安全信息

其他信息

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化学结构图

化学属性

别名和识别编码

分类

产品应用

相关文献及参考

安全信息

其他信息

系列性分类

相关产品推荐

Products Indices

Mailings

Contact

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