• 原料直供
• 试剂商城
• 直接询价

分类

• {uni_hamburg} no charge; metal-organic; 1fragment
• {SNA} Chemical Synthesis, Organometallic Reagents, Organotin, Organotins, Reduction, Synthetic Reagents, Tin Hydrides
• {SA} Chemical Synthesis, Organometallic Reagents, Organotin, Organotins, Reduction, Synthetic Reagents, Tin Hydrides
• {SNA} Chemical Synthesis, Metal Hydrides, Reduction, Synthetic Reagents

产品应用

• 广泛使用的自由基试剂，可用于还原裂解、自由基脱卤以及分子内自由基环化。

相关文献及参考

• Dialdehydes and keto aldehydes undergo free-radical intramolecular pinacol coupling to give cyclic diols: J. Am. Chem. Soc., 117, 7283 (1995); J. Org. Chem., 63, 6357 (1998).
• Merck: 14,10451 Beilstein:4(4)4312
• {
• Short: III/38A
• TBTH also cleaves other C-heteroatom bonds, controlled by the stability of the resulting radical: Nitro-groups at tertiary centers are readily cleaved: Synthesis, 693 (1986). Azides are readily reduced to amines: Synlett, 342 (1991). C-S and C-Se bonds are also cleaved. J. Am. Chem. Soc., 104, 2046 (1982); 112, 4008 (1990); J. Org. Chem., 49, 5206 (1984); 54, 1234 (1989).
• Short: III/35C4
• Reducing agent and source of tributyltin radicals. Widely used for selective reduction of alkyl halides to alkanes by a radical chain mechanism. The reaction is tolerant of a wide range of functionality, including OH and NH, in contrast to polar metal hydride reagents. For reviews, see: Synthesis, 499 (1970); 665 (1987). For a brief feature on uses of this reagent in synthesis, see: Synlett, 173 (2007). For use in the synthesis of deoxy sugars via reductive rearrangement of glycosyl bromides, see: Org. Synth. Coll., 8, 583 (1993). Cyclization of the initially-formed alkyl radical to a suitably positioned double bond may occur. Formation of 5-membered rings is strongly favoured, and ring closure onto an existing ring gives the cis-fused product. See, e.g.: J. Am. Chem. Soc., 108, 5893 (1986):
• Free-radical hydrostannylation of alkenes occurs with TBTH to give alkylstannanes. The reaction is catalyzed by, e.g. Rh complexes: Chem. Lett., 881 (1988), or Pd complexes: Angew. Chem. Int. Ed., 35, 1329 (1996), and refs therein. Syn-addition to alkynes gives vinylstannanes, useful intermediates which undergo electrophilic substitution reactions with retention of configuration. Thus, iodine, NIS and NBS give vinyl halides: J. Org. Chem., 47, 404 (1982); Tetrahedron, 42, 3575 (1986), and alkyllithium compoun

安全信息

GHS Symbol

TYPE OF TEST            : LCLo - Lowest published lethal concentration
ROUTE OF EXPOSURE       : Inhalation
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 1460 mg/m3/10M
TOXIC EFFECTS :
   Sense Organs and Special Senses (Eye) - lacrimation
   Behavioral - convulsions or effect on seizure threshold
   Lungs, Thorax, or Respiration - dyspnea
REFERENCE :
   NDRC** National Defense Research Committee, Office of Scientific Research
   and Development, Progress Report.  Volume(issue)/page/year:
   NDCrc-132,FEB1942

其他信息

• Alfa Aesar:三正丁基氢化锡,97% Tri-n-butyltin hydride, 97%(688-73-3)
• 海关编码:29310095
• 用途二:还原试剂。广泛地用于还原裂解，分子内环化。
• 图谱信息:三正丁基氢锡(688-73-3)红外图谱(IR1) 三正丁基氢锡(688-73-3)质谱(MS)
• 和水反应，溶于大多数有机溶剂。
• 下游产品:3-呋喃甲醇 --> 乙基3-氟 --> 地达诺辛 --> 2-(三丁基锡)嘧啶
• Acros Organics:三正丁基氢化锡 Tri-n-butyltin hydride, 97%(688-73-3)
• F:1-10
• 用途一:常被用來进行还原性自由基反应，其应用的范围相当广泛，不仅能將化合物上特定的官能基脱去，更可对于具有π鍵的化合物进行加成反应，甚至是高位向及立体选择性的进行分子內或分子间的耦合反应。
• 三正丁基氢锡价格(试剂级):更新日期 产品编号 产品名称 包装 价格 2011/08/23 xw010251 三丁基氢化锡;氢化三丁基锡 10g 200元 2011/04/16 T1473 三丁基氢化锡(含稳定剂BHT)[还原试剂] Tributyltin Hydride (stabilized with BHT) [Reducing Reagent] 250G 2800元 2011/04/16 T1473 三丁基氢化锡(含稳定剂BHT)[还原试剂] Tributyltin Hydride (stabilized with BHT) [Reducing Reagent] 25G 500元
• Sigma Aldrich:688-73-3(sigmaaldrich)
• 敏感性:Air & Moisture Sensitive
• MSDS 信息:Tributylstannane(688-73-3).msds
• MOL 文件:688-73-3.mol
• TSCA:Yes