Dibutylamine 二丁胺

CAS 111-92-2 MFCD00009429

化学结构图

111-92-2
SMILES: CCCCNCCCC

化学属性

Mol. FormulaC8H19N
Mol. Weight129.24
Density0.76
Refractive index1.4170 to 1.4190
Autoignition Point594 °F
Vapor Density4.46 (vs air)
Boiling Point-
Vapor Pressure1.9 mmHg ( 20 °C)
Melting Point-62
Flash Point41.11°C
TSCAYes
Solubility微溶于水,溶于乙醇、乙醚。
pH:A

别名和识别编码

Chemical NameDibutylamine
CAS Number111-92-2
EC Number203-921-8
Beilstein Registry Number506001
MDL Number-
Synonym Dibutylamine di-n-butylamine dibutylamine dibutylamine hydrochloride dibutylamine phosphate (3:1) {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {PubChem} dibutylamine phosphate (3:1) {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {PubChem} dibutylamine hydrochloride {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {PubChem} dibu
PubChem Substance ID8148
Merck Number3032
Reaxys-RN506001
Chemical Name Translation二丁胺
Wiswesser Line Notation4M4
LabNetwork Molecule IDLN00199518
InChIInChI=1S/C8H19N/c1-3-5-7-9-8-6-4-2/h9H,3-8H2,1-2H3
Canonical SMILESCCCCNCCCC
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分类

  • {Chemicalbook} 农药中间体: 杀虫剂中间体: 氨基甲酸酯类杀虫剂
  • {uni_hamburg} no charge; 1fragment
  • {SNA} Amines, Building Blocks, C8, Chemical Synthesis, Nitrogen Compounds, Organic Building Blocks

产品应用

  • 用于生产医药、农药、染料、矿物浮选剂、乳化剂以及精细化学品的中间体等。用作腐蚀称职制剂,橡胶促进剂,杀虫剂,阻聚剂等。

相关文献及参考

  • Short: II/27B
  • Merck:14,3032 Beilstein:4,157
  • Merck:14,3032
  • Short: III/35B

安全信息

Signal word Danger
GHS Symbol
WGK Germany1
Safety Statements
  • S23 Do not breathe gas/fumes/vapour/spray (appropriate wording to be specified by the manufacturer) 不要吸入气体/烟雾/蒸汽/喷雾;
  • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后,立即用大量水冲洗并征求医生意见;
  • S28 After contact with skin, wash immediately with plenty of ... (to be specified by the manufacturer) 皮肤接触后,立即用大量…(由生产厂家指定)冲洗;
  • S36/37/39 Wear suitable protective clothing, gloves and eye/face protection 穿戴适当的防护服、手套和眼睛/面保护;
  • S45 In case of accident or if you feel unwell seek medical advice immediately (show the label where possible) 发生事故时或感觉不适时,立即求医(可能时出示标签);
Risk Statements
  • R10 Flammable 易燃
  • R20/21/22 Harmful by inhalation, in contact with skin and if swallowed 吸入、皮肤接触和不慎吞咽有害
  • R21/22 Harmful in contact with skin and if swallowed 皮肤接触和不慎吞咽有害
  • R23 Toxic by inhalation 吸入有毒
  • R34 Causes burns 会导致灼伤
  • R35 Causes severe burns 会导致严重灼伤
Precautionary statements
  • P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking. 远离热源/火花/明火/热的表面。——禁止吸烟。
  • P233 Keep container tightly closed. ?保持容器密闭。
  • P240 Ground/bond container and receiving equipment. 与地面接触/连接集装箱和接受设备。
  • P241 Use explosion-proof electrical/ventilating/lighting/…/equipment. 使用防爆电气/通风/照明/ .../设备。
  • P241+P242+P243
  • P242 Use only non-sparking tools. 只能使用无火花工具。
  • P243 Take precautionary measures against static discharge. 采取预防措施,防止静电放电。
  • P260 Do not breathe dust/fume/gas/mist/vapours/spray. 不要吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P262 Do not get in eyes, on skin, or on clothing. 不要接触眼睛,皮肤或衣服。
  • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
  • P264+P265
  • P270 Do not eat, drink or smoke when using this product. 使用本产品时不要吃东西,喝水或吸烟。
  • P271 Use only outdoors or in a well-ventilated area.? 只能在室外或通风良好的地方使用。
  • P273 Avoid release to the environment. 避免释放到环境中。
  • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
  • P284 Wear respiratory protection.? 佩戴呼吸保护装置。
  • P301+P312
  • P301+P316
  • P301+P317
  • P301+P330+P331
  • P301+P330+P331+P310
  • P302+P352
  • P302+P361+P354
  • P303+P361+P353
  • P303+P361+P353+P310+P363
  • P304+P312
  • P304+P340
  • P304+P340+P310
  • P305+P351+P338
  • P305+P351+P338+P310
  • P305+P354+P338
  • P307+P311
  • P308+P311
  • P308+P316
  • P310 Immediately call a POISON CENTER or doctor/physician. 立即呼救解毒中心或医生/医师。
  • P312 Call a POISON CENTER or doctor/physician if you feel unwell. 如果你感觉不适,呼叫解毒中心或医生/医师。
  • P316
  • P317
  • P320 Specific treatment is urgent (see … on this label). 紧急具体治疗(见本标签上的)。
  • P321 Specific treatment (see … on this label). 具体治疗(见本标签上的)。
  • P322 Specific measures (see …on this label). 具体治疗(见本标签上的)。
  • P330 Rinse mouth. 漱口
  • P361 Remove/Take off immediately all contaminated clothing. 立即去除/脱掉所有被污染的衣服。
  • P361+P364
  • P362+P364
  • P363 Wash contaminated clothing before reuse. 被污染的衣服洗净后方可重新使用。
  • P370+P378
  • P390 Absorb spillage to prevent material damage. 吸收溢出物,防止重大损害。
  • P403+P233
  • P403+P235
  • P405 Store locked up. 上锁保管。
  • P501 Dispose of contents/container to..… 处理内容物/容器.....
Hazard statements
  • H226 Flammable liquid and vapour 易燃液体和蒸气
  • H301 Toxic if swallowed 吞食有毒
  • H302 Harmful if swallowed 吞食有害
  • H302+H312+H332
  • H311 Toxic in contact with skin 皮肤接触中毒
  • H312 Harmful in contact with skin 皮肤接触有害
  • H314 Causes severe skin burns and eye damage 导致严重的皮肤灼伤和眼睛损伤
  • H318 Causes serious eye damage 严重伤害眼睛
  • H330 Fatal if inhaled 吸入致命
  • H332 Harmful if inhaled 吸入有害
  • H411 Toxictoaquaticlifewithlonglastingeffects 对水生生物有毒性并具有长期影响。
Personal Protective Equipment Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter
RTECSHR7780000
Packing GroupII
UN Number 2248 UN 2248 8/PG 2 UN2248
Hazard Codes 8 T Xn
Storage condition Store at room temperature {LY} Store at room temperature {} {LY} Store at room temperature {} {} {LY} Store at room temperature {} {} {} {LY} Store at room temperature {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {}
Hazard Class8/3
Warnings 危化品目录(2015)
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Administration onto the skin
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 1010 uL/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   AMIHBC AMA Archives of Industrial Hygiene and Occupational Medicine.
   (Chicago, IL)  V.2-10, 1950-54. For publisher information, see AEHLAU.
   Volume(issue)/page/year: 10,61,1954

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 189 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   RCBUAU Revista de Chimie (Bucharest).  (Rompresfilatelia, POB 12-201,
   Bucharest, Romania) V.1-    1950-  Volume(issue)/page/year: 36,667,1985

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperito

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 290 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   GISAAA Gigiena i Sanitariya.  For English translation, see HYSAAV.  (V/O
   Mezhdunarodnaya Kniga, 113095 Moscow, USSR)  V.1-    1936-
   Volume(issue)/page/year: 40(11),21,1975

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - guinea pig
DOSE/DURATION           : 230 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   GISAAA Gigiena i Sanitariya.  For English translation, see HYSAAV.  (V/O
   Mezhdunarodnaya Kniga, 113095 Moscow, USSR)  V.1-    1936-
   Volume(issue)/page/year: 40(11),21,1975

TYPE OF TEST            : Cytogenetic analysis
TEST SYSTEM             : Rodent - hamster Fibroblast
DOSE/DURATION           : 200 mg/L/48H
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 48,337,1977

TYPE OF TEST            : DNA repair
TEST SYSTEM             : Bacteria - Bacillus subtilis
DOSE/DURATION           : 5 gm/L
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 42,19,1977

Restrict 危险品

其他信息

  • 上游原料:氨 --> 正丁醇 --> 4-氯苯甲醛 --> 溴丁烷 --> 正丁胺 --> 氰氨化钙 --> 三正丁胺 --> 流量计 --> 戊腈 --> 酸性白土
  • 图谱信息:二正丁胺(111-92-2)质谱(MS) 二正丁胺(111-92-2)核磁图( 13 CNMR) 二正丁胺(111-92-2)红外图谱(IR2) 二正丁胺(111-92-2)红外图谱(IR1) 二正丁胺(111-92-2)核磁图( 1 HNMR)
  • 急性毒性:口服- 大鼠 LD50: 189 毫克/ 公斤; 口服- 小鼠 LD50: 290 毫克/ 公斤
  • 用途三:二正丁胺是一种有机合成原料,在农药上可用来合成丁硫克百威,还可用于染料、橡胶硫化促进剂(BZTP)、防老化剂(NBC)、POP聚合催化剂、抗腐蚀剂、药物以及油品添加剂二丁基二硫代氨基甲酸盐(钼、铅、锑、锌)的生产。
  • 蒸气压:1.9 mm Hg ( 20 °C)
  • 毒性分级:高毒
  • 二正丁胺价格(试剂级):更新日期 产品编号 产品名称 包装 价格 2011/08/23 80044027 二正丁胺 250ml 28.3元 2011/04/16 D0218 二丁胺 Dibutylamine 25ML 155元 2011/04/16 D0218 二丁胺 Dibutylamine 500ML 275元
  • 有氨的气味。能与水、乙醇、乙醚相混溶,溶于丙酮、乙酸乙酯、石油醚。
  • 下游产品:正丁胺 --> 三正丁胺 --> 6-溴-3,4-二氢-3-硝基-2H-苯并吡喃 --> 丁硫克百威 --> 2-(甲氧基甲基)丙烯醛 --> 2-乙基丙烯醛 --> 二丁基二硫代氨基甲酸镍 --> 双二正丁胺基二硫物 --> N,N-二丁基乙酰胺 --> 3-(二丁胺)丙胺 --> 2-N-二丁氨基乙醇 --> 二丁基二硫代氨基甲酸锌
  • 方法一:二正丁胺有两种生产方法。 正丁醇法 由正丁醇与氨作用而得。反应方程式如下:n-C 4 H 9 OH+NH 3 +H 2 →n-C 4 H 9 NH 2 +(n-C 4 H 9 ) 2 NH+(n-C 4 H 9 ) 3 N 工艺过程为:将正丁醇、氨气、氢气经流量计控制,按配比通入不锈钢反应塔,塔内填充铜镍酸性白土催化剂,反应温度在200℃左右。反应结束后将反应气体冷凝,得到的粗产品含一丁胺2%~4.82%、二丁胺17%~26%、三丁胺31%~61%,通过精馏分离可得一丁胺、二丁胺和三丁胺。 石灰氮(氰氨化钙)法 反应方程式如下:CaCN[NaOH]→Na 2 NCN[C 4 H 9 Br]→(C 4 H 9 ) 2 NCN[H 2 O]→[H 2 SO 4 ](C 4 H 9 ) 2 NH 工艺过程为:将石灰氮悬浮在冰水中,慢慢加入冷却的氢氧化钠溶液,温度保持在25℃以下,剧烈搅拌1h,得到氰氨化钠溶液。向此溶液中加入溴丁烷乙醇溶液,搅拌回流2.5h,然后进行蒸馏,将剩余物冷却吸滤,滤饼用乙醇洗涤,将滤液和洗液合并,用苯萃
  • 用途四:作用机合成中间体。用于染料、橡胶硫化促进剂、抗腐蚀剂、药物、油品添加剂的生产。该品有毒,小鼠口服LD50550mg/kg。用二丁胺生产二硫代氨基甲酸盐类促进剂,例如,二丁基二硫代氨基甲酸锌(促进剂BZ)是由促进剂TP与ZnCI2经置换而得的。而促进剂TP(二丁基二硫代氨基甲酸钠)是由二丁胺与二硫化碳和氢氧化钠反应得到的。这类产品属超促进剂,因焦烧时间太短,一般用于胶乳生产。促进剂TP与NiSO4反应可得防老剂NBC。该品在天然橡胶、丁苯、氯丁等合成橡胶中防护热、臭氧、天候的老化。二丁基二硫代氨基甲酸盐(钼、铅、锑),例如二丁铅。用作石油添加剂,有抗氧化、抗磨、抗极压的功能。促进剂TP用氧化剂铁氰化钾在低于0℃条件下氧化而生成二硫化四丁基秋兰姆。也是天然橡胶及合成橡胶的超促进剂,亦可作硫化剂。
  • 用途一:用于石油添加剂、橡胶促进剂、矿物浮选剂、腐蚀抑制剂
  • Acros Organics:二丁基胺 Di-n-butylamine, 99%(111-92-2)
  • 储运特性:包装完整、轻装轻卸; 库房通风、远离明火、高温、与氧化剂、酸分开存放
  • 刺激数据:皮肤- 兔子 10 毫克/ 24小时 重度; 眼- 兔子 250 微克 重度

系列性分类