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• 试剂商城
• 直接询价

分类

• A - D, Alphabetical, Analytical Standards, Analytical/Chromatography, Angelica, Carum, Chromatography, Citrus, Foeniculum, Life Sciences Standards, Natural Compounds, Phenylpropanes, Phytopharma Standards, Pimpinella, Standards by Plant Genus, Substance Classification
• {SNA} A - D,
• {S
• {uni_hamburg} no charge; oxygen heterocycle; carbocycle; aromatic; large ring; fused rings; 5ring; 6ring; 9ring; 10ring; 13ring; ester; lactone; ether; 1fragment
• {SNA} A - D, A-F, Alphabetical, Analytical Standards, Analytical/Chromatography, Angelica, Carum, Chromatography,
• {SNA} Citrus aurantium (Seville orange),

产品应用

• Naturally occurring analog of Psoralen ( P839800) and metabolite of 8-Methoxy Psoralen (M260795). Antipsoriatic.

相关文献及参考

• [2]. Li XJ, et al. Bergapten exerts inhibitory effects on diabetes-related osteoporosis via the regulation of the PI3K/AKT, JNK/MAPK and NF-κB signaling pathways in osteoprotegerin knockout mice. Int J Mol Med. 2016 Dec;38(6):1661-1672.
• Honigsmann, H., et al.: Br. J. Dermatol., 101, 369 (1979),
• Merck: 14,1157
• Merck: 14,1157 Beilstein:19(5)6,4
• Short: III/35C3
• Short: III/35D4
• [1]. Lee YM, et al. Effects of 5-methoxypsoralen (5-MOP) on arylamine N-acetyltransferase activity in the stomach and colon of rats and human stomach and colon tumor cell lines. In Vivo. 2005 Nov-Dec;19(6):1061-9.
• [1]. Lee YM, et al. Effects of 5-methoxypsoralen (5-MOP) on arylamine N-acetyltransferase activity in the stomach and colon of rats and human stomach and colon tumor cell lines. In Vivo. 2005 Nov-Dec;19(6):1061-9.
• [2]. Li XJ, et al. Bergapten exerts inhibitory effects on diabetes-related osteoporosis via the regulation of t

安全信息

GHS Symbol

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 8100 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   48PRAW "Psoralens in Cosmetics and Dermatology, Proceedings of the
   International Symposium, Paris, 1981," Cahn, J., et al., eds., Paris,
   Pergamon Press France, 1981  Volume(issue)/page/year: -,303,1981

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : >30 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   48PRAW "Psoralens in Cosmetics and Dermatology, Proceedings of the
   International Symposium, Paris, 1981," Cahn, J., et al., eds., Paris,
   Pergamon Press France, 1981  Volume(issue)/page/year: -,303,1981

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - guinea pig
DOSE/DURATION           : 9 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   48PRAW "Psoralens in Cosmetics and Dermatology, Proceedings of the
   International Symposium, Paris, 1981," Cahn, J., et al., eds., Paris,
   Pergamon Press France, 1981  Volume(issue)/page/year: -,303,1981

TYPE OF TEST            : Cytogenetic analysis
ROUTE OF EXPOSURE       : Intraperitoneal
TEST SYSTEM             : Rodent - mouse
DOSE/DURATION           : 900 mg/kg
REFERENCE :
   EMMUEG Environmental and Molecular Mutagenesis.  (Alan R. Liss, Inc., 41 E.
   11th St., New York, NY 10003)  V.10-    1987-  Volume(issue)/page/year:
   25,302,1995

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 5600 mg/kg
SEX/DURATION            : female 6-15 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Fertility - pre-implantation mortality (e.g. reduction in
   number of implants per female; total number of implants per corpora lutea)
   Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death,
   e.g., stunted fetus)
REFERENCE :
   48PRAW "Psoralens in Cosmetics and Dermatology, Proceedings of the
   International Symposium, Paris, 1981," Cahn, J., et al., eds., Paris,
   Pergamon Press France, 1981  Volume(issue)/page/year: -,303,1981

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 6720 mg/kg
SEX/DURATION            : female 7-18 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death,
   e.g., stunted fetus)
REFERENCE :
   48PRAW "Psoralens in Cosmetics and Dermatology, Proceedings of the
   International Symposium, Paris, 1981," Cahn, J., et al., eds., Paris,
   Pergamon Press France, 1981  Volume(issue)/page/year: -,303,1981

其他信息

• 图谱信息:佛手苷内酯(484-20-8)核磁图( 1 HNMR)
• 佛手苷内酯价格(试剂级):更新日期 产品编号 产品名称 包装 价格 2014/06/02 B2840 佛手苷内酯 Bergapten 5G 6030元 2014/06/02 B2840 佛手苷内酯 Bergapten 1G 1640元
• Sigma Aldrich:484-20-8(sigmaaldrich)
• MOL 文件:484-20-8.mol
• TCI Shanghai:佛手苷内酯 Bergapten,>;98.0%(GC)(484-20-8)
• F:8-10
• MSDS 信息:5-Methoxypsoralen(484-20-8).msds
• 上游原料:氢氧化钠 --> 盐酸 --> 乙酸乙酯 --> 甲醇 --> 硫酸 --> 二氯甲烷 --> N,N-二甲基甲酰胺 --> 碳酸钾 --> 三氯甲烷 --> 硫酸钠 --> 三乙胺 --> 氨 --> 碳酸氢钠 --> 1,4-二氧六环 --> 甲酸 --> 叔丁醇 --> 氯化锌 --> 碘化钾 --> 碘 --> 四丁基溴化铵 --> 三氟化硼乙醚 --> 醋酸钯 --> 2,6-二甲基吡啶 --> 3-溴丙烯 --> 高碘酸钠 --> 四氧化锇 --> 丙炔酸乙酯 --> 间苯三酚