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• 试剂商城
• 直接询价

分类

• {SNA} Essential
• {SNA} Chemical Synthesis, Crystal Grade Inorganics, Deprotecting Reagents, Essential Chemicals, Fluoride Sources, Metal and Ceramic Science, Potassium, Potassium Salts, Protection and Derivatization, Research Essentials, Salts, Synthetic Reagents,

产品应用

• 络合物形成剂，点滴分析钽，发酵抑制剂，食物防腐剂。

相关文献及参考

• Reviews: Fluoride ion as a base in organic synthesis: Chem. Rev., 80, 429 (1980). Alkali metal fluorides in organic synthesis: Synthesis, 169 (1983). See also Cesium fluoride, 12885.
• For use in trifluoromethylation of aromatic, allylic and ɑ-carboxy halides, see Methyl­ chlorodifluoroacetate, A18623.
• KF can also behave as a base in a wide variety of applications:
• Merck: 14,7632
• Has been used in cleavage of silyl protecting groups under phase-transfer conditions (see tert-Butyl­dimethyl­chlorosilane, A13064): J
• An active form of KF has been prepared by recrystallization from methanol followed by drying at 100oC: Tetrahedron, 51, 6363 (1995).
• Widely used in "halex" fluorination reactions for the preparation of aryl fluorides from the corresponding chlorides by heating in a dipolar aprotic solvent, e.g. tetramethylene sulfone: J. Fluorine Chem., 46, 529 (1990). Other solvents including DMSO, DMA and NMP are also successfully employed. For a review of the preparation of aryl fluorides by halogen exchange, see: Chem. Ind. (London), 518 (1986). Aryl nitro groups can also be displaced in suitable molecules: J. Org. Chem., 56, 6406 (1991). Relative rates for aromatic fluorodenitration in different solvents were found to be: DMSO >; tetramethylene sulfoxide >; DMA >; NMP >; tetramethylene sulfone >;>; acetonitrile >; DME: J. Fluorine Chem., 35, 591 (1987).
• In the Henry reaction of 1-nitropropane with an aldehyde: Org. Synth. Coll., 9, 242 (1998). For the methylenation of catechols with Dibromomethane, A10456, in DMF: Tetrahedron Lett., 3361 (1976). In an olefination reaction with 2,2,2-Trifluoroacetophenone, A11403: J. Org. Chem., 59, 2898 (1994). In combination with 18-crown-6 for selective removal of Fmoc protecting groups under mild conditions: Synth. Commun., 24, 187 (1994).
• In the Henry reaction of 1-nitropropane with an aldehyde: Org. Synth. Coll., 9, 242 (1998). For the methylenation of

安全信息

GHS Symbol

TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Amphibian - frog
DOSE/DURATION           : 420 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   CRSBAW Comptes Rendus des Seances de la Societe de Biologie et de Ses
   Filiales.  (SPPIF, B.P.22, F-41353 Vineuil, France)  V.1-    1849-
   Volume(issue)/page/year: 124,133,1937

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 245 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   XEURAQ U.S. Atomic Energy Commission, University of Rochester, Research and
   Development Reports. (Rochester, NY)  Volume(issue)/page/year: UR-154,1951

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 40030 ug/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   DZZEA7 Deutsche Zahnaerztliche Zeitschrift.  (Carl Hanser Verlag, Postfach
   860420, D-8000 Munich 86, Fed. Rep. Ger.)  V.1-    1946-
   Volume(issue)/page/year: 34,484,1979

TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - guinea pig
DOSE/DURATION           : 250 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   85KYAH "Merck Index; an Encyclopedia of Chemicals, Drugs, and Biologicals",
   11th ed., Rahway, NJ 07065, Merck & Co., Inc. 1989 Volume(issue)/page/year:
   11,1214,1989

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal

TYPE OF TEST            : Mutation in microorganisms
TEST SYSTEM             : Rodent - mouse Lymphocyte
DOSE/DURATION           : 500 mg/L
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 187,165,1987

TYPE OF TEST            : Cytogenetic analysis
TEST SYSTEM             : Rodent - rat Bone marrow
DOSE/DURATION           : 100 nmol/L
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 343,67,1995

TYPE OF TEST            : Mutation in mammalian somatic cells
TEST SYSTEM             : Rodent - mouse Lymphocyte
DOSE/DURATION           : 400 mg/L
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 187,165,1987

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE                    : 1050 mg/kg
SEX/DURATION            : female 1-21 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death,
   e.g., stunted fetus)
   Reproductive - Specific Developmental Abnormalities - other developmental
   abnormalities
REFERENCE :
   DZZEA7 Deutsche Zahnaerztliche Zeitschrift.  (Carl Hanser Verlag, Postfach
   860420, D-8000 Munich 86, Fed. Rep. Ger.)  V.1-    1946-
   Volume(issue)/page/year: 34,484,1979

其他信息

• 下游产品:氢氧化钾 --> 4-氟苯胺 --> 氯乙酸甲酯 --> 氨苄青霉素 --> 3-码啉苯硼酸四甲基二酯 --> 6-三氟甲基吡啶-3-醛 --> 4-氨基-2-氯三氟甲苯 --> 2-氯-4-硝基三氟甲苯 --> 2,3,4-三氟硝基苯 --> 4-三氟甲基烟酸 --> 除虫脲 --> 2-氯-6-三氟甲基烟酸 --> 3-氯-4-氟苯胺 --> 2,4-二氟苯胺 --> 2,6-二氟苯甲酰胺 --> 2,4-二氨基-6-氟嘧啶 --> 4-甲基-3-氨基-2-氟吡啶 --> 2-氟苯胺 --> 2,6-二氟苯腈 --> 4-氨基-2,6-二氟嘧啶 --> 2-氨基-4,6-二氟嘧啶 --> 5-溴-2-三氟甲基吡啶 --> 4-氟-2-硝基苯甲腈 --> 四甲基氟代脲六氟磷酸酯 --> 2-氟苯酚 --
• 用途五:络合物形成剂，点滴分析钽，发酵抑制剂，食物防腐剂。
• 氟化钾价格(试剂级):更新日期 产品编号 产品名称 包装 价格 2010/06/21 201352500 氟化钾 Potassium fluoride 99%, extra pure, anhydrous 250 GR 813元 2010/06/21 390811000 氟化钾 Potassium fluoride , 40 wt.% on alumina 100 GR 1906元 2010/06/21 390810250 氟化钾 Potassium flu
• MOL 文件:7789-23-3.mol
• 用途四:用于各种玻璃刻蚀,焊接助熔剂，木材防腐剂，农业杀虫剂和农药中间体、制药工业原料、以及有机氟化原料。
• 用途二:用作络合滴定隐蔽剂和食物防腐剂，也用于玻璃的雕刻
• 参考质量标准:化工行业标准HG/T2829—1997 指标名称 指标 一等品 合格品 氟化钾(HF)含量/%≥ 98.0 96.0 氯化钾(KCI)含量/%≤ 1.5 3.0 水分/%≤ 0.5 0.5 游离酸或游离碱含量(以HF计)/%≤ 0.2 0.3 (以KOH计)/%≤ 0 0.1
• F:3
• Sigma Aldrich:7789-23-3(sigmaaldrich)
• 方法一:中和法在中和池内用等量水溶解固体氢氧化钾，然后通入无水氢氟酸(或40%氢氟酸)进行反应，至Ph=7～8时，停止通人无水氢氟酸，静止沉降24h，所得澄清液(含氟化钾40%左右)送至真空蒸发器进行真空浓缩(压力为79993 Pa)、待溶液中含有大部分结晶时，再经过滤(压力为0.2～0.3 Mpa)、真空干燥(压力为79993 Pa)6h，制得氟化钾成品。其 KOH+HF→KF+H2O
• 防护措施:本品有毒，LD50=245mg/kg。对皮肤、眼睛粘膜有刺激性。 操作人员必须穿戴防护用品。具体防护措施参见氟化铝。
• 氟化钾价格(试剂级):更新日期 产品编号 产品名称 包装 价格 2010/06/21 201352500 氟化钾 Potassium fluoride 99%, extra pure, anhydrous 25
• Acros Organics:氟化钾 Potassium fluoride, anhydrous, extra pure, 99%(7789-23-3)
• 上游原料:碳酸钾 --> 氢氧化钾 --> 氢氟酸 --> 氨苄青霉素 --> 氟硅酸
• MSDS 信息:氟化钾(7789-23-3).msds
• 300目以上粉末,有毒。具有潮解性。极易溶于水而不溶于醇，可溶于氢氟酸及液氨，微溶于醇及丙酮，其水溶液呈碱性反应，能腐蚀玻璃及陶器。加热至升华温度时才少许分解，但熔融的氟化钾活性较大，能腐蚀耐火物质。与过氧化氢可形成加成物KF.H2O2。氟化钾有两种水合物；KF.2H2O和KF.4H2O。在低于40.2℃时，在水溶液中结晶可得二水物（KF.2H2O），系单斜晶体。二水物在41℃时可与自溶于结晶水中。
• 下游产品:氢氧化钾 --> 4
• 用途三:用于玻璃雕刻、食物防腐、电镀。可用作焊接助熔剂、杀虫剂、有机化合物的氟化剂、催化剂、吸收剂(吸收HF和水分)等。也是制取氟化氢钾的原料。