Butylamine 正丁胺
CAS 109-73-9 MFCD00011690
化学结构图
SMILES: CCCCN
化学属性
| Mol. Formula | C4H11N |
|---|---|
| Mol. Weight | 73 |
| Density | 0.74 |
| Refractive index | 1.4000 to 1.4040 |
| Autoignition Point | 594 °F |
| Vapor Density | 2.5 (vs air) |
| Boiling Point | 78 |
| Vapor Pressure | 68 mmHg ( 20 °C) |
| Melting Point | -49 |
| Flash Point | -4°C(lit.) |
| TSCA | Yes |
| Solubility | 与水混溶，可混溶于醇、乙醚。 |
| Stability | 对湿度敏感 |
别名和识别编码
| Chemical Name | Butylamine |
|---|---|
| CAS Number | 109-73-9 |
| EC Number | 203-699-2 |
| Beilstein Registry Number | 605269 |
| MDL Number | MFCD00011690 |
| Synonym | 1-AMINOBUTANE 1-Aminobutane, n-Butylamine 1-BUTANAMINE 1-Butanamine 1-Butanaminen-butilamina 1-amino-1,1-dimethylethane 1-butylamine 1-丁胺 1-氨基丁烷 1-氨基丁烷 正丁胺 1-胺丁烷 2-Amino-2-methylpropan BA BUTYLAMINE, N Butanamine Butyl amine Butylamin FEMA 3130 MNBA Mono-n-butylamine Monobutilamina Monobutylamine N-BUTYLAMINE Norvalamine RARECHEM AL BW 0075 n-Butilamina n-Butylamine 一正丁基胺 丁胺 正丁氨 正丁胺 正丁胺,一正丁基胺,丁胺,1-氨基丁烷 正丁胺; 一正丁基胺; 丁胺; 1-氨基丁烷 |
| PubChem Substance ID | 8007 |
| Merck Number | 1543 |
| Reaxys-RN | 605269 |
| Chemical Name Translation | 正丁胺 |
| InChIKey | HQABUPZFAYXKJW-UHFFFAOYSA-N |
| Wiswesser Line Notation | Z4 |
| LabNetwork Molecule ID | LN00196413 |
| InChI | InChI=1S/C4H11N/c1-2-3-4-5/h2-5H2,1H3 |
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信息真实价格透明
资金保障
专业采购外包团队在线服务
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分类
- {SNA} A-B, A-D, Alphabetical Listings, Flavors and Fragrances, Halal Certified Products, Kosher Certified Products
- {uni_hamburg} no charge; 1fragment
- {SNA} A - D, A-B, A-D, Alphabetical Listings, Flavors and Fragrances, Halal Certified Products, Kosher Certified Products
产品应用
- 检验氰化物及某些铂金属。工业上用于生产医药、农药、染料、矿物浮选剂、乳化剂以及精细化学品的中间体等。
相关文献及参考
- Short: II/27B
- Merck:14,1543 Beilstein:4,156
- Merck:14,1543
- Short: III/20a
安全信息
GHS Symbol
- S16 Keep away from sources of ignition - No smoking 远离火源，禁止吸烟；
- S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后，立即用大量水冲洗并征求医生意见；
- S29 Do not empty into drains 不要排入下水道；
- S3 Keep in a cool place 保存在阴凉处；
- S36/37/39 Wear suitable protective clothing, gloves and eye/face protection 穿戴适当的防护服、手套和眼睛/面保护；
- S45 In case of accident or if you feel unwell seek medical advice immediately (show the label where possible) 发生事故时或感觉不适时，立即求医（可能时出示标签）；
- R11 Highly flammable 非常易燃
- R20/21/22 Harmful by inhalation, in contact with skin and if swallowed 吸入、皮肤接触和不慎吞咽有害
- R35 Causes severe burns 会导致严重灼伤
- R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
- P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking. 远离热源/火花/明火/热的表面。——禁止吸烟。
- P233 Keep container tightly closed. ?保持容器密闭。
- P240 Ground/bond container and receiving equipment. 与地面接触/连接集装箱和接受设备。
- P241+P242+P243
- P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
- P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
- P270 Do not eat, drink or smoke when using this product. 使用本产品时不要吃东西，喝水或吸烟。
- P271 Use only outdoors or in a well-ventilated area.? 只能在室外或通风良好的地方使用。
- P273 Avoid release to the environment. 避免释放到环境中。
- P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
- P301+P330+P331+P310
- P303+P361+P353
- P304+P340
- P304+P340+P310
- P305+P351+P338
- P305+P351+P338+P310
- P308+P311
- P310 Immediately call a POISON CENTER or doctor/physician. 立即呼救解毒中心或医生/医师。
- P370+P378
- P403+P233
- P501 Dispose of contents/container to..… 处理内容物/容器.....
- H314 Causes severe skin burns and eye damage 导致严重的皮肤灼伤和眼睛损伤
- H332 Harmful if inhaled 吸入有害
- H225 Highly flammable liquid and vapour 高度易燃液体和蒸气
- H312 Harmful in contact with skin 皮肤接触有害
- H302 Harmful if swallowed 吞食有害
- H290 May be corrosive to metals 可能腐蚀金属。
- H311+H331
TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 800 mg/kg TOXIC EFFECTS : Tumorigenic - equivocal tumorigenic agent by RTECS criteria Lungs, Thorax, or Respiration - tumors Skin and Appendages - tumors REFERENCE : BCPCA6 Biochemical Pharmacology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.1- 1958- Volume(issue)/page/year: 2,168,1959
TYPE OF TEST : LC50 - Lethal concentration, 50 percent kill ROUTE OF EXPOSURE : Inhalation SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 800 mg/m3/2H TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : 85GMAT "Toxicometric Parameters of Industrial Toxic Chemicals Under Single Exposure," Izmerov, N.F., et al., Moscow, Centre of International Projects, GKNT, 1982 Volume(issue)/page/year: -,28,1982
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Administration onto the skin SPECIES OBSERVED : Rodent - rabbit DOSE/DURATION : 850 uL/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : UCDS** Union Carbide Data Sheet. (Union Carbide Corp., 39 Old Ridgebury Rd., Danbury, CT 06817) Volume(issue)/page/year: 7/19/1965
TYPE OF TEST : LCLo - Lowest published lethal concentration ROUTE OF EXPOSURE : Inhalation SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 4000 ppm/4H TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : JIHTAB Journal of Industrial Hygiene and Toxicology. (Cambridge, MA) V.18-31, 1936-49. For publisher information, see AEHLAU. Volume(issue)/page/
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 366 mg/kg TOXIC EFFECTS : Behavioral - convulsions or effect on seizure threshold Behavioral - ataxia Lungs, Thorax, or Respiration - respiratory depression REFERENCE : TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 63,150,1982
TYPE OF TEST : LD50
TYPE OF TEST : Cytogenetic analysis ROUTE OF EXPOSURE : Oral TEST SYSTEM : Rodent - rat DOSE/DURATION : 110 mg/kg REFERENCE : ZKKOBW Zeitschrift fuer Krebsforschung und Klinische Onkologie. (Berlin, Fed. Rep. Ger.) V.76-92, 1971-78. For publisher information, see JCROD7. Volume(issue)/page/year: 86,47,1976
其他信息
- 图谱信息:正丁胺(109-73
- 用途五:检验氰化物及某些铂金属。工业上用于生产医药、农药、染料、矿
- 正丁胺价格(试剂级):更新日期 产品编号 产品名称 包装 价格 2011/08/23 80024027 正丁胺;1-丁胺;1-氨基丁烷 250ml 18.4元 2011/08/23 xp400216 正丁胺;1-丁胺;1-氨基丁烷 5ml 30元 2011/04/16 B0707 正丁胺 Butylamine 25ML 155元
- 用途四:医药中间体，用于抗糖尿病药物的生产；农药中间体，用于氨基甲酸酯类除草剂、杀虫剂的生产；助剂中间体，用于制取裂化汽油的防胶剂、添加剂、汽油抗氧剂、橡胶阻聚剂、硅氧烷弹性体硫化剂、肥皂乳化剂；用正丁胺中和载色剂的酸度可控制醇酸和尿素磁漆的粘度；正丁胺的脂肪酸皂是有色金属浮选剂；正丁胺也是彩色相片的显影剂。美国大陆石油公司用正丁胺作脱蜡的选择性溶剂及原油破乳的表面张力抑制剂。
- 爆炸物危险特性:与空气混合可爆
- FEMA:3130
- 职业标准:TWA 15 毫克/ 立方米
- 防护措施:本品有毒，具强碱性和腐蚀性，溶液或其蒸气强烈刺激人眼、皮肤和粘膜。吸入大量蒸气会引起头痛、恶心，严重者引起肺水肿。皮肤接触后应用大量水冲洗，溅入眼中，用流水至少冲洗15分钟，吸入中毒者应立即移到新鲜空气处，并请医生治疗。大鼠经口LD50为500mg/kg
- 海关编码:29211980
- F:34
- 方法一:其制备方法是将丁醇、氨和氢气在170～200℃通过载体为白土的Cu-Ni催化剂，得到三种胺即正丁胺、二正丁胺和三正丁胺的混合物，将产物进行分馏而得到正丁胺、二正丁胺和三正丁胺的产品。反应方程式：C 4 H 9 OH+NH 3 [H 2 ]→C 4 H 9 NH 2 [C 4 H 9 OH]→(C 4 H 9 ) 2 NH[C 4 H 9 OH]→(C 4 H 9 ) 3 N 或用丁醇为原料，经与氯化氢反应生成氯丁烷，将含氨的乙醇、氨水和氯丁烷压入高压釜搅拌升温至85～95℃，压力为539～637kPa，保持6h，冷却，反应完毕，将反应液加热回收氨气，然后加入盐酸至pH＝3～4，再回收乙醇，于此粗液中加入碱液至pH＝11～12，分出上层液，经蒸馏收集95℃以下馏分为正丁胺产品。反应方程式：C 4 H 9 OH+HCl→C 4 H 9 Cl+H 2 O C 4 H 9 Cl+NH 3 [C 2 H 5 OH]→CH 3 (CH 2 ) 3
- 敏感性:Air Sensit
- 蒸气密度:2.5 (vs air)
- 急性毒性:口服- 大鼠 LD50: 366 毫克/ 公斤; 口服- 小鼠 LD50: 430 毫克/ 公斤
- Sigma Aldrich:109-73-9(sigmaaldrich)
- TCI Shanghai:正丁胺 Butylamine,>;99.0%(GC)(109-73-9)
- 类别:易燃液体
- Acros Organics:正丁胺 n-Butylamine, 99.8%(109-73-9)
- {C
- 刺激数据:眼睛- 兔子 250 微克/ 24小时 重度; 皮肤-兔 500 毫克 重度
- 上游原料:氢氧化钠 --> 氢氧化铵 --> 氨 --> 正丁醇 --> Α-球蛋白 --> 酸性氧化铝 --> 4-氯苯甲醛 --> 高岭土 --> 二正丁胺 --> 1-氯丁烷 --> 乙醇95% --> 三氧化钼 --> 三正丁胺
- 下游产品:苄嘧磺隆 --> 氯磺隆 --> 二正丁胺 --> 异氰酸正丁酯 --> 姜黄素 --> 三正丁胺 --> 紫外光氧化降解含FEDBC光敏剂的低密度聚乙烯薄膜 --> 辛伐他汀 --> 卡别多巴 --> 2-氟苯基丙酮 --> 邻甲氧基苯丙酮 --> 丁吡卡因 --> 叔丁基异氰酸酯 --> 溶剂蓝 35 --> 透明蓝
- Alfa Aesar:1-丁胺,99% 1-Butylamine, 99%(109-73-9)
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