• 原料直供
• 试剂商城
• 直接询价

分类

• {SNA} Analytical and Industrial Enzymes, Biochemicals and Reagents, Cholinesterase Substrates, Cholinesterase and Organophosphate Detection Reagents, Elettaria Cardamomum (Cardamom), Miscellaneous Reagents and Supplements, Natural / Colorimetric Substrates, Phytochemicals by Plant (Food/Spice/Herb), 细胞培养, 细胞生物学, 营养研究, 试剂和添加剂, 酶、抑制剂和底物
• A-AM, Activity, Bioactive Small Molecules, Biochemicals and Reagents, Cell Biology, Chromogenic, Enzyme Substrates, Enzymes, Inhibitors, and Substrates
• {Chemicalbook} 生物化学品: 生化试剂: 核糖、核苷酸及其他类
• {SNA} Analytical Standards, Analytical/Chromatography, Chromatography, EP St

产品应用

• 内在的神经递质。

相关文献及参考

• [2]. A Young, et al. Diarrhoea of famine and malnutrition--investigations using a rat model. 2--Ileal hypersecretion induced by starvation. Gut. 1990 Feb;31(2):162-9.
• [3]. Xia Lei, et al. Effects of acetylcholine chloride on intracellular calcium concentration of cultured sweat gland epithelial cells. Arch Dermatol Res. 2008 Aug;300(7):335-41.
• [4]. P F Zabrodskii, et al. Effect of acetylcholine on mortality of mice from sepsis and proinflammatory cytokine production. Bull Exp Biol Med. 2011 Jan;150(3):340-2.
• [5]. Zhaolin Chen, et al. Inhibition of p53 Mutant Peptide Aggregation In Vitro by Cationic Osmolyte Acetylcholine Chloride. Protein Pept Lett. 2017;24(4):353-357.
• Aldrich MSDS 1 , 19:B / Corp MSDS 1 (1), 35:D / FT-IR 1 (1), 678:C / FT-IR 2 (1), 1130:A / FT-NMR 1 (1), 1078:A / IR-Spectra (2), 350:H / IR-Spectra (3), 396:E / RegBook 1 (1), 773:H / Sax 6 , 96 / Sigma FT-IR 1 (2), 1:C / Structure Index 1 ,

安全信息

GHS Symbol

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 22 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JPETAB Journal of Pharmacology and Experimental Therapeutics.  (Williams &
   Wilkins Co., 428 E. Preston St., Baltimore, MD 21202)  V.1-    1909/10-
   Volume(issue)/page/year: 58,337,1936

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 10 mg/kg
TOXIC EFFECTS :
   Peripheral Nerve and Sensation - spastic paralysis with or without sensory
   change
REFERENCE :
   JPETAB Journal of Pharmacology and Experimental Therapeutics.  (Williams &
   Wilkins Co., 428 E. Preston St., Baltimore, MD 21202)  V.1-    1909/10-
   Volume(issue)/page/year: 119,541,1957

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 170 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JPETAB Journal of Pharmacology and Experimental Therapeutics.  (Williams &
   Wilkins Co., 428 E. Preston St., Baltimore, MD 21202)  V.1-    1909/10-
   Volume(issue)/page/year: 58,337,1936

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 2500 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JPETAB Journal of Pharmacology and Experimental Therapeutics.  (Williams &
   Wilkins Co., 428 E. Preston St., Baltimore, MD 21202)  V.1-    1909/10-
   Volume(issue)/page/year: 58,337,1936

TYPE OF TEST

其他信息

• Sigma Aldrich:60-31-1(sigmaaldrich)
• 毒性分级:中毒
• 方法一:以氯乙醇和三甲胺水溶液为起始原料反应，再经乙酸酐酰化，最后精制而成。
• 溶于冷水，可被热水和碱分解，溶于乙醇、氯仿（18.2 g/l，23 °C)。实际上不溶于醚。
• 类别:有毒物品
• 参考质量标准:氯含量19.3%-19.8%；乙酰基含量23.2%-24.2%；mp149-152℃；检测水溶液反应、乙醇溶解试验及灼烧残渣等杂质含量。
• 用途一:用作测定乙酰胆碱酯酶的底物；临床作为胆碱能药物。
• 敏感性:Hygroscopic
• Alfa Aesar:氯化乙酰胆碱,98+% Acetylcholine chloride, 98+%(60-31-1)
• TCI Shanghai:氯化乙酰胆碱 Acetylcholine Chloride,>;98.0%(T)(60-31-1)
• 储运特性:库房通风低温干燥
• 可燃性危险特性:可燃; 加热分解释放有毒氮氧化物和氯化物烟雾
• Acetylcholine chloride, more commonly referred to as just acetylcholine, is a cholinergic neurotransmitter that can induce the opening of calcium channels, as well as act on nicotinic and muscarinic acetylcholine receptors. Acetylcholine plays an important role at many sites in the central nervous system. The compound has been shown to have ophthalmological uses and can be broken down quickly by choliesterases. Studies show that non-neuronal acetylcholine influences many basic cells functions, such as mitosis, cells differentiation, cytoskeletal organization, and cell to cell contact, among other functions.
• 氯化乙酰胆碱价格(试剂级):更新日期 产品编号 产品名称 包装 价格 2011/08/23 69000281 氯化乙酰胆碱（+4℃）（阴凉） 5g 80元 2011/04/16 A0084 氯化乙酰胆碱 Acetylcholine Chloride 25G 284元 2011/04/16 A0084 氯化乙酰胆碱 Acetylcholine Chloride 500G 2740元
• MOL 文件:60-31-1.mol
• 上游原料:乙醇 --> 乙酰氯 --> 2-氯乙醇 --> 三甲胺 --> 红霉素月桂酸酯
• 图谱信息:氯化乙酰胆碱(60-31-1)红外图谱(IR3) 氯化乙酰胆碱(60-31-1)核磁图( 13 CNMR) 氯化乙酰胆碱(60-31-1)红外图谱(IR2) 氯化乙酰胆碱(60-31-1)核磁图( 1 HNMR) 氯化乙酰胆碱(60-31-1)质谱(MS) 氯化乙酰胆碱(60-31-1)红外图谱(IR1)
• F:3-8-10-21
• Acros Organics:氯化乙酰胆碱 Acetylcholine chloride, 99%(60-31-1)
• 急性毒性:口服- 大鼠 LD50: 2500 毫克/ 公斤; 口服-小鼠 LD50: 3000 毫克/公斤
• 灭火剂:干粉、泡沫、砂土、二氧化碳, 雾状水
• 用途二:内在的神经递质。