Hexamethonium bromide 溴化六甲双铵

CAS 55-97-0 MFCD00011787

化学结构图

55-97-0
SMILES: C[N+](C)(C)CCCCCC[N+](C)(C)C.[Br-].[Br-]

化学属性

Mol. FormulaC12H30Br2N2
Mol. Weight362.19
Density1.422
Melting Point-285 °C
TSCAYes

别名和识别编码

Chemical NameHexamethonium bromide
Synonym Hexamethonium (Bromide) {LY} Hexamethonium (Bromide) Hexamethonium Bitartrate Hexamethonium Bromide Hexamethonium Chloride Hexamethonium Dibromide Hexamethonium Dibromide Dihydrate Hexamethonium Dichloride Dihydrate Hexamethonium Dihydroxide Hexamethonium Diiodide Hexamethonium Dimethylsulfate Hexamethonium Diperchlorate Hexamethonium Iodid {} {LY} Hexamethonium (Bromide) {} {} {LY} Hexamethonium (Bromide) {} {} {} {LY} Hexamethonium (Bromide) {} {} {} {} {LY} Hexamethonium (Bromide) {} {} {} {} {} {} {} {} {} {} {LY} Hexamethonium (Bromide) {} {} {} {} {} {} {LY} Hexamethonium (Bromide) {} {} {} {} {} {} {} {LY} Hexamethonium (Bromide) {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Hexamethonium (Bromide) {} {} {} {} {} {} {} {} {} {LY} Hexamethonium (Bromide) {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Hexamethonium (
MDL NumberMFCD00011787
CAS Number55-97-0
EC Number200-249-7
Beilstein Registry Number3715749
PubChem Substance ID5938
Merck Number4688
Reaxys-RN3715749
Chemical Name Translation溴化六甲双铵
Wiswesser Line Notation1K1&1&6K1&1&1 &E 2
LabNetwork Molecule IDLN01347834
Canonical SMILESC[N+](C)(C)CCCCCC[N+](C)(C)C.[Br-].[Br-]
InChIInChI=1S/C12H30N2.2BrH/c1-13(2,3)11-9-7-8-10-12-14(4,5)6;;/h7-12H2,1-6H3;2*1H/q+2;;/p-2
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分类

  • {SNA} Antagonists, Bioactive Small Molecules, Cell Biology, Cell Signaling and Neuroscience, Cholinergics, H, Ion Channels, Ligand-Gated Ion Channels, Neuroscience, Neurotransmission, Neurotransmitters, Nicotinic Acetylcholine Receptor Modulators
  • {SNA} Antagonists,
  • {SA} Ammonium Salts, Bioactive Small Molecules, Cell Biology, Chemical Synthesis, H, Phase Transfer Catalysts, Synthetic Reagents
  • {SNA} Antagonists, Cholinergics, H, Ion Channels, Ligand-Gated Ion Channels, Neuroscience, Neurotransmission,

安全信息

Signal word Warning
GHS Symbol
WGK Germany2
Safety Statements
  • S22 Do not breathe dust 不要吸入粉尘;
  • S24/25 Avoid contact with skin and eyes 避免皮肤和眼睛接触;
  • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后,立即用大量水冲洗并征求医生意见;
  • S36/37/39 Wear suitable protective clothing, gloves and eye/face protection 穿戴适当的防护服、手套和眼睛/面保护;
Risk Statements
  • R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
Precautionary statements
  • P260 Do not breathe dust/fume/gas/mist/vapours/spray. 不要吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
  • P270 Do not eat, drink or smoke when using this product. 使用本产品时不要吃东西,喝水或吸烟。
  • P305+P351+P338
  • P307+P311
  • P308+P311
  • P308+P316
  • P321 Specific treatment (see … on this label). 具体治疗(见本标签上的)。
  • P405 Store locked up. 上锁保管。
  • P501 Dispose of contents/container to..… 处理内容物/容器.....
RTECSBQ8575000
Personal Protective Equipment Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
Hazard statements
  • H303 May be harmfully swallowed 吞食可能有害
  • H370 Causes damage to organs 导致器官损伤
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 50300 ug/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   SKNEA7 Shionogi Kenkyusho Nenpo.  Annual Report of Shionogi Research
   Laboratory.  (Shionogi Seiyaku K.K. Kenkyusho, 5-12-4 Sagisu, Fukushima-ku,
   Osaka 553, Japan)  No.1-    1951-  Volume(issue)/page/year: 10,15,1960

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 838 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   NIIRDN Drugs in Japan (Ethical Drugs).  (Yakugyo Jiho Co., Ltd., Tokyo,
   Japan)  Volume(issue)/page/year: 6,356,1982

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 2891 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   SKNEA7 Shionogi Kenkyusho Nenpo.  Annual Report of Shionogi Research
   Laboratory.  (Shionogi Seiyaku K.K. Kenkyusho, 5-12-4 Sagisu, Fukushima-ku,
   Osaka 553, Japan)  No.1-    1951-  Volume(issue)/page/year: 10,15,1960

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 22 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   BCPCA6 Biochemical Pharmacology.  (Pergamon Press Inc., Maxwell House,
   Fairview Park, Elmsford, NY 10523)  V.1-    1958-  Volume(issue)/page/year:
   2,233,1959

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE O

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Human - woman
DOSE                    : 46 mg/kg
SEX/DURATION            : female 31-34 week(s) after conception
TOXIC EFFECTS :
   Reproductive - Specific Developmental Abnormalities - gastrointestinal
   system
   Reproductive - Effects on Newborn - other neonatal measures or effects
REFERENCE :
   ADCHAK Archives of Disease in Childhood.  (British Medical Journal, POB
   560B, Kennebunkport, ME 04046)  V.1-    1926-  Volume(issue)/page/year:
   29,354,1954

Storage condition 2-8°C, sealed storage, away from moisture {LY} 2-8°C, sealed storage, away from moisture {} {LY} 2-8°C, sealed storage, away from moisture {} {} {LY} 2-8°C, sealed storage, away from moisture {} {} {} {LY} 2-8°C, sealed storage, away from moisture {} {} {} {} {LY} 2-8°C, sealed storage, away from moisture {} {} {} {} {} {LY} 2-8°C, sealed storage, away from moisture {} {} {} {} {} {} {LY} 2-8°C, sealed storage, away from moisture {} {} {} {} {} {} {} {LY} 2-8°C, sealed storage, away from moisture {} {} {} {} {} {} {} {} {LY} 2-8°C, sealed storage, away from moisture {} {} {} {} {} {} {} {} {} {LY} 2-8°C, sealed storage, away from moisture {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C, sealed storage, away from moisture {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C, sealed storage, away from moisture {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C, sealed storage, away from moisture {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C, sealed

其他信息

  • Sigma Aldrich:55-97-0(sigmaaldrich)
  • 上游原料:乙醇 --> 乙酸乙酯 --> 氢溴酸 --> 氢氧化钙 --> 三甲胺 --> 1,6-己二醇 --> 三甲胺盐酸盐 --> 1,6-二溴己烷
  • Acros Organics:Hexamethonium bromide hydrate, 98+%(55-97-0)
  • 溴化六甲铵价格(试剂级):更新日期 产品编号 产品名称 包装 价格 2014/06/02 H0481 溴化六甲铵 Hexamethonium Bromide 500G 5310元 2014/06/02 H0481 溴化六甲铵 Hexamethonium Bromide 25G 568元 2010/06/21 204705000 溴化六甲铵 Hexamethonium bromide hydrate 98+% 500 GR 8363元
  • MOL 文件:55-97-0.mol
  • 检测方法:Silver Method
  • 图谱信息:溴化六甲铵(55-97-0)红外图谱(IR1) 溴化六甲铵(55-97-0)质谱(MS) 溴化六甲铵(55-97-0)红外图谱(IR2)
  • TCI Shanghai:溴化六甲铵 Hexamethonium Bromide,>;98.0%(T)(55-97-0)

系列性分类


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