Gallamine Triethiodide 加拉碘铵

CAS 65-29-2 MFCD00011832

化学结构图

65-29-2
SMILES: CC[N+](CC)(CC)CCOc1cccc(OCC[N+](CC)(CC)CC)c1OCC[N+](CC)(CC)CC.[I-].[I-].[I-]

化学属性

Mol. FormulaC30 H60 N3 O3 . 3 I
Mol. Weight891.53
Melting Point235
SolubilityDMSO 178 mg/mL Water 178 mg/mL Ethanol <1 mg/mL

别名和识别编码

Chemical NameGallamine Triethiodide
MDL NumberMFCD00011832
CAS Number65-29-2
PubChem Substance ID24277837
EC Number200-605-1
Synonym (v-Phenenyltris(oxyethylene))tris(triethylammonium iodide) 1,2,3-Tri(beta-diethylaminoethoxy)benzene triethiodide 1,2,3-Tris(2-diethylaminoethoxy)benzene triethiodide 1,2,3-Tris(2-diethylaminoethoxy)benzene tris(ethyliodide) 1,2,3-Tris(2-triethylammonium ethoxy)benzene triiodide 2-[2,6-Bis(2-triethylazaniumylethoxy)phenoxy]ethyl-triethylazanium triiodide 3.697 R.P. Benzcurine iodide F 2559 Flacedil Flaxedil Fourneau 2559 Gallamin Gallamin triethiodide Gallamine Gallamine Triethiodide {hazard_com} Gallamine triiodoethylate Gallamine-3ETI RP 3697 Relaxan Remyolan Retensin Sincurarine Syncurarine Tri {} {hazard_com} Gallamine triethiodid
Chemical Name Translation加拉碘铵
Wiswesser Line Notation2K2&2&2O 3 B CR &I &I &I &2/18 &2/21 &2/24
LabNetwork Molecule IDLN00197342
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分类

  • {SNA} Antagonists,
  • {SNA} Antagonists, Bioactive Small Molecules, Cell Signaling and Neuroscience, Cholinergics, G, Neuroscience, Neurotransmission, Neurotransmitters, 细胞生物学
  • {SNA} Antagonists, Bioactive Small Molecule Alphabetical Index, Cholinergics, G, Neuroscience, Neurotransmission, Neurotransmitters, 生物活性小分子, 细胞信号转导和神经科学,
  • {SNA} Analytical Standards, EP Standards, EP Standards G - H, Pharmacopeia Metrological Institutes Standards, 分析/色谱
  • {SNA} Antagonists, Bioactive Small Molecule Alphabetical Index, Cholinergics,

相关文献及参考

  • [1]. http://en.wikipedia.org/wiki/Gallamine_triethiodide

安全信息

GHS Symbol
WGK Germany3
Hazard statements
  • H302 Harmful if swallowed 吞食有害
  • H315 Causes skin irritation 会刺激皮肤
  • H335 May cause respiratory irritation 可能导致呼吸道刺激
  • H319 Causes serious eye irritation 严重刺激眼睛
Personal Protective Equipment dust mask type N95 (US), Eyeshields, Gloves
RTECSBS1100000
Precautionary statements
  • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P301+P312+P330
  • P305+P351+P338
Signal word Warning
Hazard Codes Xn
Safety Statements
  • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后，立即用大量水冲洗并征求医生意见；
  • S36 Wear suitable protective clothing 穿戴适当的防护服；
  • S45 In case of accident or if you feel unwell seek medical advice immediately (show the label where possible) 发生事故时或感觉不适时，立即求医（可能时出示标签）；
Risk Statements
  • R22 Harmful if swallowed 吞咽有害
  • R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
Storage condition +4°C 储存温度-20°C 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 28500 ug/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   NIIRDN Drugs in Japan (Ethical Drugs).  (Yakugyo Jiho Co., Ltd., Tokyo,
   Japan)  Volume(issue)/page/year: 6,178,1982

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 440 ug/kg
TOXIC EFFECTS :
   Sense Organs and Special Senses (Eye) - effect, not otherwise specified
   Behavioral - altered sleep time (including change in righting reflex)
   Behavioral - rigidity (including catalepsy)
REFERENCE :
   IJNEAQ International Journal of Neuropharmacology.  (New York, NY)  V.1-8,
   1962-69.  For publisher information, see NEPHBW.  Volume(issue)/page/year:
   5,305,1966

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : >1 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   NIIRDN Drugs in Japan (Ethical Drugs).

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraduodenal
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 380 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans
   Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium)  V.4-   
   1898-  Volume(issue

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION

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其他信息

  • 加拉碘铵

系列性分类

  1. Life Science 生命科学
  2. Cell Biology 细胞生物学
  3. Bioactive Small Molecules - Cell Biology
  4. G - Bioactive Small Molecules
  1. Medical Research Areas
  2. GPCR & G Protein
  3. mAChR  (毒蕈碱型乙酰胆碱受体)

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