Hydrazodicarbothioamide 二硫代脲

CAS 142-46-1 MFCD00014471

化学结构图

142-46-1
SMILES: NC(=S)NNC(N)=S

化学属性

Mol. FormulaC2H6N4S2
Mol. Weight150.22
Melting Point212°C
TSCAYes
Appearance 双硫脲纯品为白色结晶固体,m.p.206~208℃,在热水中有一定的溶解度,易溶于吡啶、三乙胺、二甲基甲酰胺及一般溶剂中。
Density1.556

别名和识别编码

Chemical NameHydrazodicarbothioamide
MDL NumberMFCD00014471
CAS Number142-46-1
EC Number205-537-6
Beilstein Registry Number1723178
PubChem Substance ID87567830
Synonym bithiourea 2,5-二硫代脲 bisthiocarbamylhydrazine USAF B-55 1,2-HYDRAZINEDICARBOTHIOAMIDE DITHIOCARBAMOYL HYDRAZINE 1,2-HYDRAZINE CARBOTHIOAMIDE usafb-44 usafek-p-6281 2,5-二硫代二脲 Bis(thiourea) 1,2-HYDRAZINE-O-DICARBOTHIOAMIDE 2,5-dithio-biure usafb-55 DITHIOBIUREA 1,2-Hydrazinedicarbothioamide; 2,5-Dithiobiurea 2,5-二硫代联二脲 1,2-Hydrazinedicarbothioamide 2,5-Dithiobiurea ZERENEX ZX007400 2,5-dithiodiurea 2,5-DITHIOBIUREA Bisthiocarbamyl hydrazine n,n’-bisthiocarbamylhydrazine 双硫脲 DITHIOUREA BISTHIOUREA nci-c03009 DITHIODIUREA TIMTEC-BB SBB008379 2,5-二硫二脲 1,2-二(氨基硫代甲酰)肼 NCI-C03009 N,N'-Bisthiocarbamyl hydrazine
Reaxys-RN1723178
Chemical Name Translation二硫代脲
Wiswesser Line NotationSUYZMMYZUS
LabNetwork Molecule IDLN00223016
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分类

  • {Chemicalbook} 农药中间体: 杀菌剂中间体: 其他类杀菌剂

产品应用

  • 农药和医药中间体。

相关文献及参考

  • Beilstein: 3,196

安全信息

RTECSEC1460000
Safety Statements
  • S37/39 Wear suitable gloves and eye/face protection 穿戴适当的手套和眼睛/面保护;
  • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后,立即用大量水冲洗并征求医生意见;
  • S36 Wear suitable protective clothing 穿戴适当的防护服;
Risk Statements
  • R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
  • R22 Harmful if swallowed 吞咽有害
WGK Germany3
GHS Symbol
Precautionary statements
  • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
  • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
  • P302+P350
  • P302+P352+P332+P313+P362+P364
  • P305+P351+P338
  • P305+P351+P338+P337+P313
  • P332+P313
  • P337+P313
  • P362 Take off contaminated clothing and wash before reuse. 脱掉污染的衣服,清洗后方可重新使用
Signal word Warning
Hazard statements
  • H315 Causes skin irritation 会刺激皮肤
  • H319 Causes serious eye irritation 严重刺激眼睛
  • H335 May cause respiratory irritation 可能导致呼吸道刺激
Personal Protective Equipment dust mask type N95 (US), Eyeshields, Gloves
Hazard Codes Xi
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 655 gm/kg/78W-C
TOXIC EFFECTS :
   Tumorigenic - equivocal tumorigenic agent by RTECS criteria
   Liver - tumors
REFERENCE :
   NCITR* National Cancer Institute Carcinogenesis Technical Report Series.
   (Bethesda, MD)  No.0-205. For publisher information, see NTPTR*.
   Volume(issue)/page/year: NCI-TR-132,1979

TYPE OF TEST            : TD - Toxic dose (other than lowest)
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 1310 gm/kg/78W-C
TOXIC EFFECTS :
   Tumorigenic - equivocal tumorigenic agent by RTECS criteria
   Liver - tumors
REFERENCE :
   NCITR* National Cancer Institute Carcinogenesis Technical Report Series.
   (Bethesda, MD)  No.0-205. For publisher information, see NTPTR*.
   Volume(issue)/page/year: NCI-TR-132,1979

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 100 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   NTIS** National Technical Information Service.  (Springfield, VA 22161)
   Formerly U.S. Clearinghouse for Scientific & Technical Information.
   Volume(issue)/page/year: AD277-689

TYPE OF TEST            : LD - Lethal dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : >500 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   NCNSA6 National Academy of Sciences, National Research Council,
   Chemical-Biological Coordination Center, Review.  (Washington, DC)
   Volume(issue)/page/year: 5,46,1953

TYPE OF TEST            : Sister chromatid exchange
TEST SYSTEM             : Rodent - hamster Ovary
DOSE/DURATION           : 145 mg/L
REFERENCE :
   EMMUEG Environmental and Molecular Mutagenesis.  (Alan R. Liss, Inc., 41 E.
   11th St., New York, NY 10003)  V.10-    1987-  Volume(issue)/page/year:
   10(Suppl 10),1,1987

其他信息

  • 图谱信息:2,5-二硫代联二脲(142-46-1)核磁图( 13 CNMR) 2,5-二硫代联二脲(142-46-1)质谱(MS) 2,5-二硫代联二脲(142-46-1)红外图谱(IR1) 2,5-二硫代联二脲(142-46-1)红外图谱(IR2)
  • 下游产品:川化-108 --> 2-氨基-5-巯基-1,3,4-噻二唑
  • 上游原料:硫氰酸铵 --> 硫酸肼 --> 硫氰酸胺
  • 类别:农药
  • 用途一:双硫脲是杀菌剂叶枯唑的中间体。
  • 方法一:其制备方法是在反应釜中于搅拌下投入湿基硫酸肼,加入催化剂少量,然后再投入硫氰酸铵,开夹套蒸汽加热回流3.5h,冷却,放料,过滤,用水洗涤,真空吸滤至干,得成品。
  • Alfa Aesar:二硫代脲,97% 2,5-Dithiobiurea, 97%(142-46-1)
  • 用途二:农药和医药中间体。
  • 毒性分级:高毒
  • 急性毒性:口服-大鼠 LD50: 500 毫克/公斤;腹腔-小鼠 LD50: 100 毫克/公斤
  • 储运特性:库房通风低温干燥; 与氧化剂、酸类分开存放
  • 可燃性危险特性:受热分解排放有毒氮氧化物和硫氧化物
  • 灭火剂:水,干粉、干砂、二氧化碳、泡沫、1211灭火剂
  • 方法二:硫酸肼和硫氰酸胺经缩合、重排出得。
  • 2,5-二硫代联二脲价格(试剂级):更新日期 产品编号 产品名称 包装 价格 2014/06/02 D1308 2,5-二硫代联二脲 2,5-Dithiobiurea 25G 383元 2014/06/02 D1308 2,5-二硫代联二脲 2,5-Dithiobiurea 10G 195元 2010/05/25 A16667 二硫代脲, 97% 2,5-Dithiobiurea, 97% 25g 344元
  • TCI Shanghai:2,5-二硫代联二脲 2,5-Dithiobiurea(142-46-1)
  • Sigma Aldrich:142-46-1(sigmaaldrich)
  • MOL 文件:142-46-1.mol
  • 几乎不溶于水,溶于热水。

系列性分类


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