1-(4-Hydroxyphenyl)-3-Phenylprop-2-en-1-One 1-(4-羟基苯基)-3-苯基丙-2-烯-1-酮

CAS 2657-25-2 MFCD00016484

化学结构图

2657-25-2
SMILES: O=C(/C=C/c1ccccc1)c1ccc(O)cc1

化学属性

Mol. FormulaC15H12O2
Mol. Weight224.26
Melting Point175-177
Density1.422
TSCANo

别名和识别编码

Chemical Name1-(4-Hydroxyphenyl)-3-Phenylprop-2-en-1-One
CAS Number2657-25-2
Alfabeta NameHYDROXYCHALCONE 4-'
MDL NumberMFCD00016484
EC Number250-023-7
Beilstein Registry Number2049150
Reaxys-RN2049150
PubChem Substance ID5282362
Synonym 1-(4-Hydroxyphenyl)-3-phenyl-2-propen-1-one 2-BENZAL-4'-HYDROXYACETOPHENONE 2-BENZYLIDENE-4'-HYDROXYACETOPHENONE 4'-HYDROXYCHALCONE 4'-Hydroxychalcone {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {}
Chemical Name Translation1-(4-羟基苯基)-3-苯基丙-2-烯-1-酮
InChIKeyUAHGNXFYLAJDIN-IZZDOVSWSA-N
LabNetwork Molecule IDLN01099889
InChIInChI=1S/C15H12O2/c16-14-9-7-13(8-10-14)15(17)11-6-12-4-2-1-3-5-12/h1-11,16H/b11-6+
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品牌质保精细包装    现货库存    一流品牌服务   

分类

  • {SNA} Building Blocks, C9 to C20+, Chemical Synthesis, Organic Building Blocks, Oxygen Compounds, Phenols
  • Building Blocks, C9 to C20+, Chemical Synthesis, New Products for Chemical Synthesis, Organic Building Blocks, Oxygen Compounds, Phenols

相关文献及参考

  • [2]. Ali Reza, et al. Hepatoprotective activity of phloretin and hydroxychalcones against Acetaminophen Induced hepatotoxicity in mice. Iranian Journal of Pharmaceutical Sciences. 2011 Jan; 7(2).
  • [3]. Orlikova B, et al. The aromatic ketone 4'-hydroxychalcone inhibits TNFα-induced NF-κB activation via proteasome inhibition. Biochem Pharmacol. 2011 Sep 15;82(6):620-31.
  • [1]. Inoue B, et al. The effects of echinatin and its related compounds on the mitochondrial energy transfer reaction. J Toxicol Sci. 1982 Nov;7(4):245-54.
  • [1]. Inoue B, et al. The effects of echinatin and its related compounds on the mitochondrial energy transfer reaction. J Toxicol Sci. 1982 Nov;7(4):245-54.
  • [2]. Ali Reza, et al. Hepatoprotective activity of phloretin and hydroxychalcones against Acetaminophen Induced hepatotoxicity in mice. Iranian Journal of Pharmaceutical Sciences. 2011 Jan; 7(2).
  • [3]. Orlikova B, et al. The aromatic ketone 4'-hydroxychalcone inhibits

安全信息

Signal word
GHS Symbol
WGK Germany3
Safety Statements
  • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后，立即用大量水冲洗并征求医生意见；
  • S37 Wear suitable gloves 戴适当手套；
  • S36/37/39 Wear suitable protective clothing, gloves and eye/face protection 穿戴适当的防护服、手套和眼睛/面保护；
  • S37/39 Wear suitable gloves and eye/face protection 穿戴适当的手套和眼睛/面保护；
Risk Statements
  • R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
Precautionary statements
  • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
  • P362 Take off contaminated clothing and wash before reuse. 脱掉污染的衣服，清洗后方可重新使用
  • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
  • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P305+P351+P338
  • P332+P313
  • P305+P351+P338+P337+P313
  • P302+P350
  • P337+P313
  • P321 Specific treatment (see … on this label). 具体治疗（见本标签上的）。
  • P501 Dispose of contents/container to..… 处理内容物/容器.....
  • P302+P352
  • P405 Store locked up. 上锁保管。
Hazard statements
  • H315 Causes skin irritation 会刺激皮肤
Hazard Codes Xi

其他信息

  • Alfa Aesar:4'-羟基查耳酮,97% 4'-Hydroxychalcone, 97%(2657-25-2)
  • Acros Organics:4-羟苯基苯丙烯酮 4'-Hydroxychalcone, 98%(2657-25-2)
  • MOL 文件:2657-25-2.mol
  • 图谱信息:4-羟基查耳酮(2657-25-2)红外图谱(IR1) 4-羟基查耳酮(2657-25-2)红外图谱(IR2) 4-羟基查耳酮(2657-25-2)质谱(MS)
  • TCI Shanghai:4'-羟基查耳酮 4'-Hydroxychalcone,>;95.0%(GC)(2657-25-2)
  • 4-羟基查耳酮价格(试剂级):更新日期 产品编号 产品名称 包装 价格 2014/06/02 H0945 4'-羟基查耳酮 4'-Hydroxychalcone 5G 662元 2010/06/21 372530010 4-羟基查耳酮 4'-Hydroxychalcone 98% 1 GR 228元 2010/06/21 372530050 4-羟基查耳酮 4'-Hydroxychalcone 98% 5 GR 611元

系列性分类

  1. Chemical Synthesis 化学合成
  2. Building Blocks 合成砌块
  3. Organic Building Blocks 有机砌块
  4. Oxygen Compounds 氧化合物
  5. Phenols 酚类
  6. C9 to C20+ - Phenols
  1. Chemical Synthesis 化学合成
  2. Building Blocks 合成砌块
  3. Organic Building Blocks 有机砌块
  4. Halogenated Hydrocarbons 卤代烃
  5. Aryl 芳基卤代烃
  1. Life Science 生命科学
  2. Biochemistry / Glyco-Chemistry
  3. Flavonoids
  1. Medical Research Areas
  2. Metabolism
  3. Proteasome  (蛋白酶体)

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