Auramine Auramine

CAS 492-80-8 MFCD00036224

化学结构图

492-80-8
SMILES:

化学属性

Mol. FormulaC17H21N3
Mol. Weight267.41
Melting Point138 ºC
Density1.01

别名和识别编码

Chemical Nameanalytical standard
Synonym C.I. Basic Yellow 2, Free Base TETRAMETHYL44DIAMINODIPHENYLMETHYLENEIMINE 奥拉明O 4,4'-碳亚氨基二[N,N-二甲基]苯胺 Apyonin Auramin 4,4'-carbonimidoylbis[N,N-dimethylaniline] C.I. Solvent Yellow 34 4,4'-dimethylaminobenzophenonimide 4,4'-(Imidocarbonyl)bis(N,N-dimethylaniline); 4,4'-Dimethylaminobenzophenonimide; Auramine N Base; Auramine O Base; Auramine OAF; Auramine SS; Auramine base; Baso Yellow 124; Brilliant Oil Yellow; C.I. 41000B; Orient Oil Yellow 101; Solvent Yellow 34; Waxoline Brilliant Oil Yellow 4,4'-(imidocarbonyl)bis(n,n-dimethyl-anilin C.I. Basic Yell 4,4'-Dimethylaminobenzophenonimide 4,4'-Carbonimidoyl 4,4'-carbonimidoylbis(n,n-dimethylbenzenamine) Auramine OAF 4,4'-Dimethylaminobenzophenonimide 4,4'-(Imidocarbonyl)bis(N,N-Dimethylaniline) C.I.碱性黄2 Auramine SS 4,4'-二甲基氨基二苯甲酮亚胺 溶剂黄 34 Carbonoimidoylbis(N,N-dimethylbenzenamine) {uni C.I.41000:1 4,4'-(Imidocarbonyl)bis(N,N-dimethylaniline) C.I. 41000B {Chemical Benzenamine, 4,4’-carbonimidoylbis [N,N-dimethyl- 碱性嫩黄 4,4'-Carbonimidoylbis[N,N-dimethylanilin] Bis(p-dimethylaminophenyl)methyleneimine Auremine {h {haz Auramine Waxoline yellow D Auramine base 4,4'-carbonimidoylbis[N,N-dimethylaniline] Tetramethyldiaminodiphenylacetimine 4,4'-carbonimidoylbis[N,N-dimethyl-Benzenamine 4, 4 -Carbonimdoylbis[N,N-dimethylaniline] Benzenamine, 4,4'-carbonimidoylbis[N,N-dimethyl- Blauramine Auramine Base
CAS Number492-80-8
Beilstein Registry Number2215338
MDL NumberMFCD00036224
EC Number207-762-5
Chemical Name TranslationAuramine
Wiswesser Line Notation1N1&R DYUM&R DN1&1
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分类

  • {SNA} Alphabetical Index of Analytical Standards, Chemical Class, A, AR to AZ, All Alphabetically Sorted, All alphabetical sorted, Analytical Standards, Analytical/Chromatography, Aromatics, Chromatography, Colors, Food & Beverage Standards, Food Color Additives, Life Sciences Standards, Other banned artificial food dyes
  • {uni_hamburg} no charge; carbocycle; aromatic; 6RingOnly; 6ring; 1fragment
  • {SNA} A, AR to AZ, All Alphabetically Sorted, All alphabetical sorted, Alphabetical Index of Analytical Standards, Analytical Standards, Analytical/Chromatography, Aromatics, Chemical Class,
  • {SNA} A,
  • {SNA

相关文献及参考

  • Short: III/5b Title: Structure Data of Organic Crystals: C 14 ... C 120 Author: Schudt, E.; Weitz, G. Editor: Hellwege, K.-H.; Hellwege, A.M. Source: Landolt-Börnstein, New Series Volume: III/5b Year: 1971 ISBN: 3-540-05177-5 ISBN: 978-3-540-05177-0 Internet Resource: DOI:10.1007/b19970 RefComment: XXI, 736 pages, and VII, 890 pages. Hardcover Abstract: Volume III/5 offers a compitation as complete as possible of the space groups and lattice con-stants of all crystals which have been studied by means of X-rays, neutron and electron diffraction.
  • Short: EINECS Title: EINECS (European Inventory of Existing Commercial Chemical Substances) Source: Official Journal of the European Communities Volume: C 146 A (15.06.1990) Page: 1 Year: 1990 Internet Resource: http://ecb.jrc.ec.europa.eu/esis/index.php?PGM=ein Publish_Date: 1990/06/15

安全信息

Hazard statements
  • H351 Suspected of causing cancer 怀疑致癌
  • H411 Toxictoaquaticlifewithlonglastingeffects 对水生生物有毒性并具有长期影响。
  • H302 Harmful if swallowed 吞食有害
  • H319 Causes serious eye irritation 严重刺激眼睛
GHS Symbol
Precautionary statements
  • P305+P351+P338
  • P273 Avoid release to the environment. 避免释放到环境中。
  • P281 Use personal protective equipment as required. 使用所需的个人防护装备。
WGK Germany3
Signal word Warning
RTECSBY3500000
Personal Protective Equipment Eyeshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges
Safety Statements
  • S61 Avoid release to the environment. Refer to special instructions/safety data sheet 避免释放到环境中，参考特别指示/安全收据说明书；
  • S36/37 Wear suitable protective clothing and gloves 穿戴适当的防护服和手套；
Hazard Codes Xn,N
Risk Statements
  • R51/53
  • R36 Irritating to eyes 刺激眼睛
  • R22 Harmful if swallowed 吞咽有害
  • R40 Limited evidence of a carcinogenic effect 有限证据表明其致癌作用
TYPE OF TEST            : TD - Toxic dose (other than lowest)
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 42 gm/kg/50W-C
TOXIC EFFECTS :
   Tumorigenic - equivocal tumorigenic agent by RTECS criteria
   Liver - tumors
REFERENCE :
   AICCA6 Acta Unio Internationalis Contra Cancrum.  (Louvain, Belgium) V.1-20,
   1936-64.  For publisher information, see IJCNAW. Volume(issue)/page/year:
   19,483,1963

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 263 mg/kg/21W-C
TOXIC EFFECTS :
   Tumorigenic - equivocal tumorigenic agent by RTECS criteria
   Tumorigenic - tumors at site of application
REFERENCE :
   AICCA6 Acta Unio Internationalis Contra Cancrum.  (Louvain, Belgium) V.1-20,
   1936-64.  For publisher information, see IJCNAW. Volume(issue)/page/year:
   19,483,1963

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 29 gm/kg/52W
TOXIC EFFECTS :
   Tumorigenic - neoplastic by RTECS criteria
   Liver - tumors
   Blood - lymphoma, including Hodgkin's disease
REFERENCE :
   BJCAAI British Journal of Cancer.  (Macmillan Press Ltd., Houndmills,
   Basingstoke, Hants. RG21 2XS, UK)  V.1-    1947-  Volume(issue)/page/year:
   10,653,1956

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 37 gm/kg/87W-C
TOXIC EFFECTS :
   Tumorigenic - equivocal tumorigenic agent by RTECS criteria
   Tumorigenic - tumor types after systemic administration not seen
   spontaneously
REFERENCE :
   AICCA6 Acta Unio Internationalis Contra Cancrum.  (Louvain, Belgium) V.1-20,
   1936-64.  For publisher information, see IJCNAW

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 3 gm/kg
TOXIC EFFECTS :
   Behavioral - convulsions or effect on seizure threshold
   Behavioral - changes in motor activity (specific assay)
   Behavioral - muscle weakness
REFERENCE :
   TLSMA6 Trudy Leningradskogo Sanitarno-Gigienicheskogo Meditsinskogo
   Instituta.  (Leningrad, Russia) V.1-145, 1949-82.  Discontinued.
   Volume(issue)/page/year: 105,45,1974

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 103 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   PMRSDJ Progress in Mutation Research.  (Elsevier Science Pub. Co., Inc., 52
   Vanderbilt Ave., New York, NY 10017)  V.1-    1981- Volume(issue)/page/year:
   1,682,1981

TYPE OF TEST            : Mutation in microorganisms
TEST SYSTEM             : Bacteria - Salmonella typhimurium
DOSE/DURATION           : 250 ug/plate
REFERENCE :
   PMRSDJ Progress in Mutation Research.  (Elsevier Science Pub. Co., Inc., 52
   Vanderbilt Ave., New York, NY 10017)  V.1-    1981- Volume(

TYPE OF TEST            : DNA damage
TEST SYSTEM             : Bacteria - Bacillus subtilis
DOSE/DURATION           : 2 mg/disc
REFERENCE :
   PMRSDJ Progress in Mutat

TYPE OF TEST            : DNA inhibition
ROUTE OF EXPOSURE       : Oral
TEST SYSTEM             : Rodent - mouse
DOSE/DURATION           : 500 mg/kg
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 46,305,1977

TYPE OF TEST            : Gene conversion and mitotic recombination
TEST SYSTEM             : Yeast - Saccharomyces cerevisiae
DOSE/DURATION           : 78 ppm
REFERENCE :
   PMRSDJ Progress in Mutation Research.  (Elsevier Science Pub. Co., Inc., 52
   Vanderbilt Ave., New York, NY 10017)  V.1-    1981- Volume(issue)/page/year:
   1,481,1981

TYPE OF TEST            : Phage inhibition capacity
TEST SYSTEM             : Bacteria - Escherichia coli
DOSE/DURATION           : 300 mg/L
REFERENCE :
   CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut
   Sts., Philadelphia, PA 19106)  V.1-    1941-  Volume(issue)/page/year:
   41,532,1981

TYPE OF TEST            : Unscheduled DNA synthesis
TEST SYSTEM             : Human Fibroblast
DOSE/DURATION           : 20 mg/L
REFERENCE :
   TXCYAC Toxicology.  (Elsevier Scientific Pub. Ireland, Ltd., POB 85,
   Limerick, Ireland) V.1-    1973-  Volume(issue)/page/year: 21,151,1981

TYPE OF TEST            : Morphological transformation
TEST SYSTEM             : Rodent - hamster Embryo
DOSE/DURATION

其他信息

  • 用途一:主要用于醋纤、棉织品的染色，还用于纸张、皮革、油漆等的着色
  • MOL 文件:492-80-8.mol
  • Sigma Aldrich:492-80-8(sigmaaldrich)

系列性分类

  1. Analytical & Chromatography 分析化学与色谱
  2. Analytical Standards
  3. Alphabetic - Analytical Standards
  4. A - Alphabetic
  5. AR to AZ - A

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