2,5-Dioxopyrrolidin-1-yl 4-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)butanoate N-(4-马来酰亚胺丁酰基)琥珀酰亚胺

CAS 80307-12-6 MFCD00036817

化学结构图

80307-12-6
SMILES: O=C(CCCN1C(=O)C=CC1=O)ON1C(=O)CCC1=O

化学属性

Mol. FormulaC12H12N2O6
Mol. Weight280
Melting Point123-129
TSCANo
Density1.422

别名和识别编码

Chemical Name2,5-Dioxopyrrolidin-1-yl 4-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)butanoate
CAS Number80307-12-6
Synonym 4-Maleimidobutyric Acid N-Hydroxysuccimide Ester 4-Maleimidobutyric acid N-hydroxysuccinimide ester 4-Maleimidobutyric acid N-succinimidyl ester N-(γ-Maleimidobutyryloxy)succinimide N-Succinimidyl 4-maleimidobutyrate GMBS 4-Maleimidobutyric acid N-succinimidyl ester, 4-Maleimidobutyric acid NHS GMBS N-(4-Maleimidebutyryloxy)succinimide
MDL NumberMFCD00036817
PubChem Substance ID87575906
Beilstein Registry Number6427689
Reaxys-RN6427689
EC Number250-023-7
Chemical Name TranslationN-(4-马来酰亚胺丁酰基)琥珀酰亚胺
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分类

  • MTS & Sulfhydryl Active Reagents
  • {SNA} Chemical Biology, Chemical Synthesis, Crosslinkers, Linkers and Crosslinkers
  • Cross Linking Reagents
  • Maleimide Derivatives

产品应用

  • A short, sulfhydryl and amino reactive heterobifunctional crosslinking reagent. Introduces maleimide groups into IgM.

相关文献及参考

  • Keller, O., et al.: Helv. Chim. Acta., 58, 531 (1975),

安全信息

WGK Germany3
GHS Symbol
Precautionary statements
  • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
  • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
  • P305+P351+P338
  • P305+P351+P338+P337+P313
  • P362 Take off contaminated clothing and wash before reuse. 脱掉污染的衣服，清洗后方可重新使用
Hazard statements
  • H315 Causes skin irritation 会刺激皮肤
  • H319 Causes serious eye irritation 严重刺激眼睛
  • H335 May cause respiratory irritation 可能导致呼吸道刺激
Signal word Warning
Personal Protective Equipment dust mask type N95 (US), Eyeshields, Gloves
Safety Statements
  • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后，立即用大量水冲洗并征求医生意见；
  • S36 Wear suitable protective clothing 穿戴适当的防护服；
  • S36/37/39 Wear suitable protective clothing, gloves and eye/face protection 穿戴适当的防护服、手套和眼睛/面保护；
  • S37 Wear suitable gloves 戴适当手套；
  • S60 This material and its container must be disposed of as hazardous waste 该物质及其容器必须作为危险废物处置；
Hazard Codes Xi
Risk Statements
  • R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
Storage condition -20°C 0-10 0-10°C

系列性分类

  1. Life Science 生命科学
  2. Proteomics 蛋白质组学
  3. Protein Structural Analysis - Proteomics
  4. Protein Modification - Protein Structural Analysis
  5. Crosslinking - Protein Modification
  6. Heterobifunctional Cross-Linking Reagents - Crosslinking
  1. Chemical Synthesis 化学合成
  2. Chemical Biology 生物化学
  3. Peptide Chemistry 多肽化学
  4. Linkers - Peptide Chemistry
  5. Crosslinkers - Linkers and Crosslinkers

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