4-(3-(4-Butoxyphenoxy)Propyl)Morpholine Hydrochloride 4-(3-(4-丁氧基苯氧基)丙基)吗啉盐酸盐

CAS 637-58-1 MFCD00054323

化学结构图

637-58-1
SMILES: CCCCOc1ccc(OCCCN2CCOCC2)cc1.Cl

化学属性

Mol. FormulaC17H27NO3.ClH
Mol. Weight329.91
SolubilityDMSO 66 mg/mL Water 66 mg/mL Ethanol 66 mg/mL

别名和识别编码

Chemical Name4-(3-(4-Butoxyphenoxy)Propyl)Morpholine Hydrochloride
MDL NumberMFCD00054323
CAS Number637-58-1
PubChem Substance ID73957
EC Number211-293-1
Synonym 4-(3-(p-Butoxyphenoxy)propyl)-morpholine hydrochloride PRAXOMINE HYDROCHLORIDE 普莫卡因 盐酸盐 gamma-Morpholinopropyl 4-n-butoxyphenyl ether hydrochloride PRAMOXINE HYDROCHLORIDE 普莫卡因 盐酸盐;盐酸普莫卡因; 4-丁氧基苯基-gamma-吗啉丙基醚盐酸盐 Proxazocaine hydrochloride 4-丁氧基苯基-gamma-吗啉丙基醚盐酸盐 Tronothane hydrochloride Proctofoam 4-n-Butoxyphenylg-morpholinopropyletherhydrochlorideusp 4-n-butoxyphenyl gamma-morpholinopropyl ether hydrochloride 盐酸普莫卡因 4-n-Butoxyphenyl gamma-morpholinopropyl ether hydrochloride 4-[3-(P-BUTOXYPHENOXY)PROPYL]MORPHOLINE HYDROCHLORIDE proctofoam PRAMOXINEHYDROCHLORIDE,USP PRAMOXINE HCL MORPHOLINE,4-(3-(PARA-BUTOXYPHENOXY)PROPYL)-,HYDROCHLORIDE PRAMOXINE HCL USP TRONOTHANE HYDROCHLORIDE 普莫卡因 HCL 4-(3-(p-butoxyphenoxy)propyl)-morpholinhydrochloride TRONOTHANE HYDROCHLORIDE USP 4-[3-(P-BUTOXYPHENOXY)PROPYL]MORPHOLINE HYDROCHLORIDE USP gamma-morpholinopropyl4-n-butoxyphenyletherhydrochloride p-Butoxyphenyl gamma-morpholinopropyl ether hydrochloride p-butoxyphenylgamma-morpholinopropyletherhydrochloride 普莫卡因 pramocaine hydrochloride Pramocaine HCl;Morpholine, 4-[3-(4-butoxyphenoxy)propyl]-, hydrochloride (1:1) 4-[3-(4-Butoxyphenoxy)propyl]morpholine hydrochloride Pramoxine hydrochloride 4-N-BUTOXYPHENYL G-MORPHOLINOPROPYL ETHER HYDROCHLORIDE
Chemical Name Translation4-(3-(4-丁氧基苯氧基)丙基)吗啉盐酸盐
Wiswesser Line NotationT6N DOTJ A3OR DO4 &GH
LabNetwork Molecule IDLN01310055
InChIInChI=1S/C17H27NO3.ClH/c1-2-3-12-20-16-5-7-17(8-6-16)21-13-4-9-18-10-14-19-15-11-18;/h5-8H,2-4,9-15H2,1H3;1H
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分类

  • {SNA} Analytical Standards, Chromatography, Pharmaceutical Secondary Standards,
  • {SNA} Alphabetical Index of Analytical Standards, Analytical Standards, P, PON - PT, 分析/色谱
  • {SNA} Alphabetical Index of Analytical Standards, Analytical Standards, Analytical/Chromatography, P, PON - PT
  • {SNA} Analytical Standards, Analytical/Chromatography, Chromatography, Pharmaceutical Secondary Standards, Pharmaceutical Standards
  • {SNA} Additional Standards, Analytical Standards, Chromatography, Pharmaceutical Secondary Standards, Pharmaceutical Standards, Pharmacopeia Metrological Institutes Standards, Secondary Standards, 分析/色谱
  • {SNA} Additional Standards, Analytic

安全信息

WGK Germany3
GHS Symbol
Precautionary statements
  • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P305+P351+P338
Hazard statements
  • H315 Causes skin irritation 会刺激皮肤
  • H335 May cause respiratory irritation 可能导致呼吸道刺激
  • H302 Harmful if swallowed 吞食有害
  • H319 Causes serious eye irritation 严重刺激眼睛
RTECSQD8750000
Signal word Warning
Personal Protective Equipment dust mask type N95 (US), Eyeshields, Gloves
Hazard Codes Xi,Xn Xn Xi
Safety Statements
  • S36 Wear suitable protective clothing 穿戴适当的防护服；
  • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后，立即用大量水冲洗并征求医生意见；
Risk Statements
  • R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
  • R22 Harmful if swallowed 吞咽有害
Storage condition 储存温度-20°C 储存温度 2-8°C 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 79500 ug/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   TXAPA9 Toxicology and Applied Pharmacology.  (Academic Press, Inc., 1 E.
   First St., Duluth, MN 55802) V.1-    1959-  Volume(issue)/page/year:
   1,454,1959

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 1470 mg/kg
TOXIC EFFECTS :
   Behavioral - convulsions or effect on seizure threshold
   Cardiac - cardiac output
   Lungs, Thorax, or Respiration - other changes
REFERENCE :
   AAREAV Anesthesie, Analgesie, Reanimation.  (Paris, France)  V.14-38,
   1957-81.  Volume(issue)/page/year: 14,225,1957

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 460 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   29ZVAB "Handbook of Analytical Toxicology," Sunshine, I., ed., Cleveland,
   OH, Chemical Rubber Co., 1969  Volume(issue)/page/year: -,99,1969

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - rabbit
DOSE/D

TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - guinea pig
DOSE/DURATION           : 109 mg/kg
TOXIC EFFECTS :
   Behavioral - convulsions or effect on seizure threshold
   Cardiac - cardiac output
   Lungs, Thorax, or Respiration - other changes
REFERENCE :
   AAREAV Anesthesie, Analgesie, Reanimation.  (Paris, France)  V.1

其他信息

  • MOL 文件:637-58-1.mol
  • Pramoxine是一种外用局部麻醉药，具有止痒效果。
  • Sigma Aldrich:637-58-1(sigmaaldrich)
  • 用途一:局部麻醉药
  • 普莫卡因 盐酸盐

系列性分类

  1. Analytical & Chromatography 分析化学与色谱
  2. Analytical Standards
  3. Chromatography - Analytical Standards
  4. Forensic and Veterinary Standards - Chromatography
  5. Drugs & Metabolites - Forensic and Veterinary Standards
  6. Neat Compounds - Drugs & Metabolites
  1. Analytical & Chromatography 分析化学与色谱
  2. Analytical Standards
  3. Alphabetic - Analytical Standards
  4. P - Alphabetic
  5. PON - PT - P

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