Demeton-S-methyl-sulfon

CAS 17040-19-6 MFCD00055415

化学结构图

17040-19-6
SMILES: CCS(=O)(=O)CCSP(=O)(OC)OC

化学属性

Mol. FormulaC6H15O5PS2
Mol. Weight262.30

别名和识别编码

Chemical NamePhosphorothioic acid, O,O-dimethylS-(2-(ethylsulfonyl)ethyl) ester
CAS Number17040-19-6
Synonym Metaisosystox-solfon 20 315 Sulfone, demeton-S-methyl- Demeton-S-methyl-sulphone Demeton-S-methylsulfon Isomethylsystox sulfone Bayer 20315 O,O-Dimethyl S-(2-ethsulfonylethyl)phosphorothioate O,O-Dimethyl-S-(2-aethylsulfonyl-aethyl)-thiolphosphat O,O-Dimethyl S-ethyl-2-sulfonylethyl phosphorothiolate E 158 磺吸磷 ######## Isometasystox sulfone M 3/158 Dimethyl S-(2-ethsulfonylethyl)thiophosphate Dioxydemeton-S-methyl O,O-Dimethyl S-ethylsulphonylethyl phosphorothiolate
MDL NumberMFCD00055415
PubChem Substance ID24868902
Beilstein Registry Number1712536
EC Number241-109-5
Wiswesser Line NotationWS2&2SPO&O1&O1
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分类

  • Inhibitors
  • Metabolites & Impurities
  • Phosphorylating and Phosphitylating Agents
  • Sulfur & Selenium Compounds
  • {SA} Acaricides, Alpha sort, Alphabetic, Analytical Standards, Analytical/Chromatography, Chromatography, D, DA - DH, Demeton metabolites, Environmental Standards, Insecticides, Metabolites, Organophorous, Pesticides, Pesticides & Metabolites, Thiometon metabolite
  • {SNA} Alphabetical Index of Analytical Standards, Acaricides, All alphabetically sorted, Analytical Standards, Analytical/Chromatography, Chromatography, D, DA - DH, Dem

产品应用

  • A metabolite of Demeton-S-methyl (D231370). An organophosphorus pesticide biomarker.

相关文献及参考

  • Edson, E.F., et al.: Pharm. J., 185, 365 (1960),
  • Pozo, O., et al.: Anal. Bioanal. Chem., 389, 1765 (2007),
  • Mezcua, M., et al.: Anal. Chem., 81, 913 (2009),

安全信息

RTECSTF9050000
GHS Symbol
Precautionary statements
  • P273 Avoid release to the environment. 避免释放到环境中。
Hazard statements
  • H411 Toxictoaquaticlifewithlonglastingeffects 对水生生物有毒性并具有长期影响。
  • H312 Harmful in contact with skin 皮肤接触有害
  • H301 Toxic if swallowed 吞食有毒
WGK Germany2
Signal word Danger
Personal Protective Equipment dust mask type N95 (US), Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges
Safety Statements
  • S61 Avoid release to the environment. Refer to special instructions/safety data sheet 避免释放到环境中,参考特别指示/安全收据说明书;
  • S45 In case of accident or if you feel unwell seek medical advice immediately (show the label where possible) 发生事故时或感觉不适时,立即求医(可能时出示标签);
  • S28 After contact with skin, wash immediately with plenty of ... (to be specified by the manufacturer) 皮肤接触后,立即用大量…(由生产厂家指定)冲洗;
  • S36/37 Wear suitable protective clothing and gloves 穿戴适当的防护服和手套;
  • S22 Do not breathe dust 不要吸入粉尘;
Hazard Codes T,N
Risk Statements
  • R51/53
  • R25 Toxic if swallowed 吞咽有毒
  • R21 Harmful in contact with skin 与皮肤接触有害
Restrict 剧毒化学品
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 50 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   85GYAV "Pflanzenschutz-und Schaedlingsbekaempfungsmittel: Abriss einer
   Toxikologie und Therapie von Vergiftungen," 2nd ed., Klimmer, O.R.,
   Hattingen, Fed. Rep. Ger., Hundt-Verlag, 1971  Volume(issue)/page/year:
   -,20,1971

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 32400 ug/kg
TOXIC EFFECTS :
   Biochemical - Enzyme inhibition, induction, or change in blood or tissue
   levels - other esterases
REFERENCE :
   BIJOAK Biochemical Journal.  (Biochemical Soc. Book Depot, POB 32, Commerce
   Way, Colchester, Essex C

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Unreported
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 40 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   30ZDA9 "Chemistry of Pesticides," Melnikov, N.N., New York, Springer-Verlag
   New York, Inc., 1971  Volume(issue)/page/year: -,347,1971

TYPE OF TEST

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Administration on

TYPE OF TEST            : LC50 - Lethal concentration, 50 percent kill
ROUTE OF EXPOSURE       : Inhalation
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 195 mg/m3/4H
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   GUCHAZ Guide to the Chemicals Used in Crop Protection.  (Information Canada,
   171 Slater St., Ottawa, Ont., Canada)  Volume(issue)/page/year: 6,165,1973

TYPE OF TEST            : Mutation in microorganisms
TEST SYSTEM             : Bacteria - Escherichia coli
DOSE/DURATION           : 5 mg/plate
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 28,405,1975

系列性分类


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