Lathosterol 7-烯胆烷醇

CAS 80-99-9 MFCD00056176

化学结构图

80-99-9
SMILES: CC(C)CCC[C@@H](C)[C@H]1CC[C@H]2C3=CC[C@H]4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C |&1:6,8,11,15,17,21,23,26|

化学属性

Mol. FormulaC27H46O
Mol. Weight386.65
Melting Point126°C
Boiling Point
Flash Point-

别名和识别编码

Chemical NameLathosterol
CAS Number80-99-9
Synonym Lathosterol {SNA} 5α-Cholest-7-en-3β-ol 5α-胆固-7-烯-3β-醇 7-Cholesten-3-beta-ol 7-En-3-cholestanol ?-Cholestenol ?7-Cholestenol Cholest-7-en-3-ol Cholest-7-en-3-ol, (3-beta,5-alpha)- Cholesterin {} {TRC} 5?-Cholest-7-en-3?-ol {} {} {SNA} 3β-Hydroxy-5α,7-cholestene Lathosterol {} {} {} {SNA} 3β-Hydroxy-5α,7-cholestene {} {} {} {} {TRC} 3?-Hydroxy-5?-cholest-7-ene {} {} {} {} {} {TRC} (3?,5?)-Cholest-7-en-3-ol {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {}
MDL NumberMFCD00056176
PubChem Substance ID24892635
Chemical Name Translation7-烯胆烷醇
Wiswesser Line NotationL E5 B666 IUTJ A1 E1 FY1&3Y1&1 OQ
InChIKeyIZVFFXVYBHFIHY-SKCNUYALSA-N
LabNetwork Molecule IDLN01305001
Canonical SMILESCC(C)CCC[C@@H](C)[C@H]1CC[C@@]2([H])C3=CC[C@@]4([H])C[C@H](O)CC[C@]4(C)[C@@]3([H])CC[C@]12C
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分类

  • Pharmaceuticals
  • {SNA} Biochemicals and Reagents, Cholesterol and Derivatives, Lipids, Metabolic Pathways, Steroid Metabolism, Sterol Lipids, 代谢组学, 细胞生物学
  • Steroids
  • {SNA} Biochemicals and Reagents, Cholesterol and Derivatives, Lipids, Metabolic Pathways, Metabolomics,

产品应用

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相关文献及参考

  • Bjorkman, M., et al.: Eur. J. Endocrinol., 158, 749 (2008),
  • Chyou, P., et al.: Age Ageing, 29, 69 (2000),
  • Schatz, I., et al.: Lancet, 358, 351 (2001),
  • [1]. Kempen HJ, et al. Serum Lathosterol concentration is an indicator of whole-body cholesterol synthesis in humans. J Lipid Res. 1988 Sep;29(9):1149-55.

安全信息

WGK Germany3
Personal Protective Equipment Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 750 mg/kg/9W-I
TOXIC EFFECTS :
   Tumorigenic - Carcinogenic by RTECS criteria
   Tumorigenic - tumors at site of application
REFERENCE :
   JNCIAM Journal of the National Cancer Institute.  (Washington, DC)  V.1-60,
   1940-78.  For publisher information, see JJIND8.  Volume(issue)/page/year:
   19,977,1957

RTECSFZ7000000
Storage condition -20°C, sealed storage, away from moisture {LY} -20°C, sealed storage, away from moisture 4 4°C 4℃ {} {LY} -20°C, sealed storage, away from moisture {} {} {LY} -20°C, sealed storage, away from moisture {} {} {} {LY} -20°C {} {} {} {} {LY} +4℃ {} {} {} {} {} {LY} +4°C

系列性分类

  1. Life Science 生命科学
  2. Biochemicals and Reagents 生化试剂
  3. Lipids - Biochemicals and Reagents
  4. Sterol Lipids - Lipids
  5. Cholesterol and Derivatives - Sterol Lipids
  1. Life Science 生命科学
  2. Biochemicals and Reagents 生化试剂
  3. Lipids - Biochemicals and Reagents
  4. Sterol Lipids - Lipids
  5. Cholesterol and Derivatives - Sterol Lipids
  1. Medical Research Areas
  2. Metabolism
  3. Endogenous Metabolite  (内源性代谢物)

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