N-(4-Hydroxy-3-Methoxybenzyl)-8-Methylnonanamide N-(4-羟基-3-甲氧基苄基)-8-甲基壬酰胺

CAS 19408-84-5 MFCD00057794

化学结构图

19408-84-5
SMILES: COC1C=C(CNC(=O)CCCC/C=C/C(C)C)C=CC=1O

化学属性

Mol. FormulaC18H29NO3
Mol. Weight307
Melting Point65-66

别名和识别编码

Chemical NameN-(4-Hydroxy-3-Methoxybenzyl)-8-Methylnonanamide
CAS Number19408-84-5
Synonym 6,7-Dihydrocapsaicin N-[(4-Hydroxy-3-methoxyphenyl)methyl]-8-methylnonenamide N-(4-羟基-3-甲氧基苄基)-8-甲基壬酰胺 8-Methyl-N-vanillylnonanamide 二氢辣椒素
MDL NumberMFCD00057794
PubChem Substance ID24278532
Beilstein Registry Number2815150
Chemical Name TranslationN-(4-羟基-3-甲氧基苄基)-8-甲基壬酰胺
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分类

  • {SNA} Bioactive Small Molecule Alphabetical Index, DIG-DY, Neurobiology, Neuroscience, Pharmacologicals, Vanilloids, 生物活性小分子, 细胞信号转导和神经科学, 细胞生物学
  • Drug Analogues
  • {SNA} Bioactive Small Molecules, Cell Biology, DIG-DY
  • Pharmaceuticals
  • Intermediates & Fine Chemicals
  • Amines
  • Aromatics
  • {SNA} Bioactive Small Molecules, Cell Biology, Cell Signaling and Neuroscience, DIG-DY, Neurobiology, Neuroscience, Pharmacologicals, Vanilloids

产品应用

  • Capsaicin (C175680) analog. A VR1 vaniloid receptor agonist.

相关文献及参考

  • Ralevic, V., et al.: Biochem. Pharmacol., 65, 143 (2003),
  • Thompson, R., et al.: Anal. Bioanal. Chem., 381, 1432 (2005),
  • Tuoya., et al.: Life Sci., 78, 1515 (2006),

安全信息

WGK Germany3
Precautionary statements
  • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P301+P310
  • P305+P351+P338
Hazard statements
  • H315 Causes skin irritation 会刺激皮肤
  • H319 Causes serious eye irritation 严重刺激眼睛
  • H301 Toxic if swallowed 吞食有毒
  • H335 May cause respiratory irritation 可能导致呼吸道刺激
RTECSRA5998000
Signal word Danger
GHS Symbol
Personal Protective Equipment Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges
Hazard Codes 6.1 T
Safety Statements
  • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后，立即用大量水冲洗并征求医生意见；
  • S36/37/39 Wear suitable protective clothing, gloves and eye/face protection 穿戴适当的防护服、手套和眼睛/面保护；
  • S45 In case of accident or if you feel unwell seek medical advice immediately (show the label where possible) 发生事故时或感觉不适时，立即求医（可能时出示标签）；
Risk Statements
  • R25 Toxic if swallowed 吞咽有毒
  • R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
UN Number 3462
Packing GroupII 
TYPE OF TEST            : Mutation in microorganisms
TEST SYSTEM             : Rodent - hamster Lung
DOSE/DURATION           : 5 mg/L
REFERENCE :
   CALEDQ Cancer Letters (Shannon, Ireland).  (Elsevier Scientific Pub. Ireland
   Ltd., POB 85, Limerick, Ireland)  V.1-    1975- Volume(issue)/page/year:
   48,109,1989

系列性分类

  1. Life Science 生命科学
  2. Cell Biology 细胞生物学
  3. Bioactive Small Molecules - Cell Biology
  4. DIG-DY - Bioactive Small Molecules
  1. Life Science 生命科学
  2. Cell Biology 细胞生物学
  3. Cell Signaling and Neuroscience - Cell Biology
  4. Neuroscience - Cell Signaling and Neuroscience
  5. Neurobiology - Neuroscience
  6. Pharmacologicals - Neurobiology
  7. Vanilloids - Pharmacologicals

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