7-(2-Hydroxy-3-((2-Hydroxyethyl)(Methyl)Amino)Propyl)-1,3-Dimethyl-1H-Purine-2,6(3H,7H)-Dione Nicotinate 7-(2-羟基-3-((2-羟基乙基)(甲基)氨基)丙基)-1,3-二甲基-1H-嘌呤-2,6-(3H,7H)-二酮烟酸盐

CAS 437-74-1 MFCD00058342

化学结构图

437-74-1
SMILES: CN(CCO)CC(O)Cn1cnc2c1c(=O)n(C)c(=O)n2C.O=C(O)c1cccnc1

化学属性

Mol. FormulaC13H21N5O4.C6H5NO2
Mol. Weight434.51

别名和识别编码

Chemical Name7-(2-Hydroxy-3-((2-Hydroxyethyl)(Methyl)Amino)Propyl)-1,3-Dimethyl-1H-Purine-2,6(3H,7H)-Dione Nicotinate
CAS Number437-74-1
Alfabeta NameHYDROXYHYDROXYETHYLMETHYLAMINOPROPYLDIMETHYLPURINEDIONENICOTINATE HHH72321312637((((()))))-----------,,,
MDL NumberMFCD00058342
EC Number207-115-7
Synonym 7-(2-Hydroxy-3-((2-hydroxyethyl)methylamino)propyl)theophylline compd. 7-(2-hydroxy-3-((2-hydroxyethyl)methylamino)propyl)theophyllinecompd.withn 7-(3-(N-(2-Hydroxyethyl)amino)-2-hydroxypropyl)thiophylline nicotinate 7-(3-(n-(2-hydroxyethyl)amino)-2-hydroxypropyl)thiophyllinenicotinate 7-[2-Hydroxy-3-(2-hydroxyethyl-methyl-amino)propyl]-1,3-dimethyl-purine-2,6-dione pyridine-3-carboxylic acid 7-[2-hydroxy-3-(2-hydroxyethyl-methyl-amino)propyl]-1,3-dimethyl-purine-2,6-dione pyridine-3-carboxylic acid 7-[2-羟基-3-(2-羟乙基-甲胺基)丙基]-1,3-二甲基-嘌呤-2,6-二酮烟酸盐 7-[2-羟基-3-(2-羟乙基-甲胺基)丙基]苯碱烟酸盐 7-[3-[(2-Hydroxyethyl)methylamino]-2-hydroxypropyl]theophyllinenicotinate 7-[3-[(2-羟乙基)甲氨基]-2-羟丙基]茶碱尼古丁酸酯 Angiomin Complamex Complamin Complamine Contamex Komplamin Niacinate, Xa
Chemical Name Translation7-(2-羟基-3-((2-羟基乙基)(甲基)氨基)丙基)-1,3-二甲基-1H-嘌呤-2,6-(3H,7H)-二酮烟酸盐
Wiswesser Line NotationT56 BN DN FNVNVJ B1YQ1N1&2Q F1 H1 &T6NJ CVQ
LabNetwork Molecule IDLN00162099
PubChem Substance ID9912
InChIInChI=1S/C13H21N5O4.C6H5NO2/c1-15(4-5-19)6-9(20)7-18-8-14-11-10(18)12(21)17(3)13(22)16(11)2;8-6(9)5-2-1-3-7-4-5/h8-9,19-20H,4-7H2,1-3H3;1-4H,(H,8,9)
信息真实价格透明    资金保障    专业采购外包团队在线服务   
信息真实价格透明    资金保障    专业采购外包团队在线服务   
品牌质保精细包装    现货库存    一流品牌服务   

安全信息

Warnings IRRITANT
RTECSQT1500000
WGK Germany2 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 3010 mg/kg
TOXIC EFFECTS :
   Behavioral - altered sleep time (including change in righting reflex)
   Lungs, Thorax, or Respiration - cyanosis
   Nutritional and Gross Metabolic - body temperature decrease
REFERENCE :
   TOIZAG Toho Igakkai Zasshi.  Journal of Medical Society of Toho University.
   (Toho Daigaku Igakkai, 21-16, Omori-nishi, 5-chome, Ota-ku, Tokyo 143,
   Japan)  V.1-    1954-  Volume(

TYPE OF TEST            : LD50 - Lethal do

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Mammal - species unspecified
DOSE/DURATION           : 900 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   PCJOAU Pharmaceutical Chemistry Journal (English Translation).  Translation
   of KHFZAN. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013)  No.1-
   1967-  Volume(issue)/page/year: 20,286,1986

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 14130 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   OYYAA2 Oyo Yakuri.  Pharmacometrics.  (Oyo Yakuri Kenkyukai, CPO Box 180,
   Sendai 980-91, Japan) V.1-    1967-  Volume(issue)/page/year: 9,601,1975

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 673 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   YHTPAD Yaoxue Tongbao. Bulletin of Pharmacology. (China International Book
   Trading

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 10 gm/kg
SEX/DURATION            : female 7-14 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Effects on Newborn - weaning or lactation index (e.g., #
   alive at weaning per # alive at day 4)
REFERENCE :
   OYYAA2 Oyo Yakuri.  Pharmacometrics.  (Oyo Yakuri Kenkyukai, CPO Box 180,
   Sendai 980-91, Japan) V.1-    1967-  Volume(issue)/page/year: 8,1145,1974

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 1920 mg/kg
SEX/DURATION            : female 7-14 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death,
   e.g., stunted fetus)
   Reproductive - Effects on Newborn - growth statistics (e.g.%, reduced weight
   gain)
REFERENCE :
   OYYAA2 Oyo Yakuri.  Pharmacometrics.  (Oyo Yakuri Kenkyukai, CPO Box 180,
   Sendai 980-91, Japan) V.1-    1967-  Volume(issue)/page/year: 8,1145,1974

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE                    : 1920 mg/kg
SEX/DURATION            : female 7-14 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death,
   e.g., stunted fetus)
   Reproductive - Specific Developmental Abnormalities - musculoskeletal system
REFERENCE :
   OYYAA2 Oyo Yakuri.  Pharmacometrics.  (Oyo Yakuri Kenkyukai, CPO Box 180,
   Sendai 980-91, Japan) V.1-    1967-  Volume(issue)/page/year: 8,1145,1974

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE                    : 40 gm/kg
SEX/

其他信息

  • MSDS 信息:Xanthinol nicotinate(437-74-1).msds
  • MOL 文件:437-74-1.mol
  • 用途一:适用于脑血栓形式等缺血性脑血管疾病及中风后遗症。

系列性分类

  1. Analytical & Chromatography 分析化学与色谱
  2. Analytical Standards
  3. Alphabetic - Analytical Standards
  4. X - Alphabetic

相关产品推荐