2,5-Dioxopyrrolidin-1-yl 2-iodoacetate N-羟基琥珀酰亚胺碘代乙酸酯

CAS 39028-27-8 MFCD00058451

化学结构图

39028-27-8
SMILES: O=C(CI)ON1C(=O)CCC1=O

化学属性

Mol. FormulaC6H6INO4
Mol. Weight283
Melting Point145-149

别名和识别编码

Chemical Name2,5-Dioxopyrrolidin-1-yl 2-iodoacetate
MDL NumberMFCD00058451
PubChem Substance ID57654310
CAS Number39028-27-8
Reaxys-RN1213727
Synonym 碘乙酸 N-羟基琥珀酰亚胺酯
Chemical Name TranslationN-羟基琥珀酰亚胺碘代乙酸酯
Beilstein Registry Number1213727
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分类

  • Active Esters/Additives, Chemical Biology, Chemical Synthesis, Coupling, Crosslinkers, Crosslinking, Heterobifunctional Cross-Linking Reagents, Linkers and Crosslinkers, Peptide Chemistry,
  • {SNA} Active Esters/
  • {SNA} Active Esters/Additives, Amine to Sulfhydryl, Chemical Biology, Chemical Synthesis,

相关文献及参考

  • Rector, E.S., et al., A method for the preparation of protein-protein conjugates of predetermined composition. J. Immunol. Methods 24 , 321-336, (1978) 摘要
  • Houen, G., et al., Conjugation to preactivated proteins using divinylsulfone and iodoacetic acid. J. Immunol. Methods 181 , 187-200, (1995) 摘要

安全信息

WGK Germany3
GHS Symbol
Precautionary statements
  • P362 Take off contaminated clothing and wash before reuse. 脱掉污染的衣服，清洗后方可重新使用
  • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
  • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P305+P351+P338
  • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
  • P332+P313
  • P302+P350
Signal word
Hazard statements
  • H315 Causes skin irritation 会刺激皮肤
  • H319 Causes serious eye irritation 严重刺激眼睛
  • H335 May cause respiratory irritation 可能导致呼吸道刺激
Hazard Codes Xi
Personal Protective Equipment dust mask type N95 (US), Eyeshields, Gloves
Storage condition <;0
Safety Statements
  • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后，立即用大量水冲洗并征求医生意见；
  • S36 Wear suitable protective clothing 穿戴适当的防护服；
Risk Statements
  • R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性

系列性分类

  1. Chemical Synthesis 化学合成
  2. Chemical Biology 生物化学
  3. Peptide Chemistry 多肽化学
  4. Peptide Coupling - Peptide Chemistry
  5. Active Esters/Additives - Peptide Coupling
  1. Life Science 生命科学
  2. Proteomics 蛋白质组学
  3. Protein Structural Analysis - Proteomics
  4. Protein Modification - Protein Structural Analysis
  5. Crosslinking - Protein Modification
  6. Heterobifunctional Cross-Linking Reagents - Crosslinking

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