4-Chloro-o-toluidine hydrochloride 4-氯-2-甲基苯胺盐酸盐

CAS 3165-93-3 MFCD00060226

化学结构图

3165-93-3
SMILES: Cc1cc(Cl)ccc1N.Cl

化学属性

Mol. FormulaC7H8ClN·HCl
Mol. Weight178.06
Solubility溶于水。

别名和识别编码

Chemical Name4-氯-2-甲基苯胺盐酸盐4-氯-2-甲基苯胺盐酸盐
MDL NumberMFCD00060226
CAS Number3165-93-3
Synonym 2-AMINO-5-CHLOROTOLUENE HYDROCHLORIDE 2-Amino-5-chlorotoluene hydrochloride 2-Methyl-4-chloroaniline hydrochloride 2-amino-5-chlorotoluenehydrochloride[qr] 2-methyl-4-c 2-methyl-4-chloroanilinehydroch 2-氨基-5-氯甲苯盐酸盐 4-CHLORO-2-METHYLANILINE HYDROCHLORIDE 4-CHLORO-O-TOLUIDINE HYDROCHLORIDE 4-Chloro-2-methylbenzenamine hydrochloride 4-Chloro-2-toluidine hydrochloride 4-Chloro-6-methylaniline hydrochlor 4-chloro-2-m 4-chloro-2-methyl-benzenaminhydrochloride[qr] 4-chloro-2-methylaniline 4-chloro-2-methylaniline hydrochloride 4-chloro-2-methylanilinehydrochloride[qr] 4-chloro-2-methylbenzenaminehydrochloride 4-chloro-2-toluidine 4-chloro-2-toluidine hydrochloride 4-chloro-2-toluidinehydrochlo
Reaxys-RN5986883
PubChem Substance ID18487
Chemical Name Translation4-氯-2-甲基苯胺盐酸盐
Wiswesser Line NotationZR DG B1 &GH
LabNetwork Molecule IDLN01740948
InChIInChI=1S/C7H8ClN.ClH/c1-5-4-6(8)2-3-7(5)9;/h2-4H,9H2,1H3;1H
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分类

  • {SNA} Amines, Building Blocks, C7, Chemical Synthesis, Nitrogen Compounds, Organic Building Blocks

安全信息

RTECSXU5250000
Packing GroupIII
Signal word Danger
UN Number 1579
Hazard statements
  • H301+H311+H331
  • H302 Harmful if swallowed 吞食有害
  • H340 May cause genetic defects 可能导致遗传性缺陷
  • H341 Suspected of causing genetic defects 怀疑导致遗传性缺陷
  • H350 May cause cancer 可能致癌
  • H370 Causes damage to organs 导致器官损伤
  • H372 Causes damage to organs through prolonged or repeated exposure 长期或频繁接触会损伤器官
  • H410 Verytoxictoaquaticlifewithlonglastingeffects 对水生生物毒性非常大并具有长期影响。
Precautionary statements
  • P201 Obtain special instructions before use. 使用前获取专门指示。
  • P202 Do not handle until all safety precautions have been read and understood. 已阅读并理解所有的安全预防措施之前,切勿操作。
  • P203
  • P260 Do not breathe dust/fume/gas/mist/vapours/spray. 不要吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P262 Do not get in eyes, on skin, or on clothing. 不要接触眼睛,皮肤或衣服。
  • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
  • P270 Do not eat, drink or smoke when using this product. 使用本产品时不要吃东西,喝水或吸烟。
  • P271 Use only outdoors or in a well-ventilated area.? 只能在室外或通风良好的地方使用。
  • P273 Avoid release to the environment. 避免释放到环境中。
  • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
  • P281 Use personal protective equipment as required. 使用所需的个人防护装备。
  • P301+P310
  • P301+P312
  • P301+P312+P330
  • P301+P316
  • P301+P317
  • P302+P317
  • P302+P352
  • P304+P340
  • P307+P311
  • P308+P311
  • P308+P313
  • P308+P316
  • P309+P311
  • P311 Call a POISON CENTER or doctor/physician. 呼叫解毒中心或医生/医师。
  • P312 Call a POISON CENTER or doctor/physician if you feel unwell. 如果你感觉不适,呼叫解毒中心或医生/医师。
  • P314 Get medical advice/attention if you feel unwell. 获取医疗咨询/就医,如果你觉得不舒服
  • P316
  • P318
  • P319
  • P321 Specific treatment (see … on this label). 具体治疗(见本标签上的)。
  • P322 Specific measures (see …on this label). 具体治疗(见本标签上的)。
  • P330 Rinse mouth. 漱口
  • P361 Remove/Take off immediately all contaminated clothing. 立即去除/脱掉所有被污染的衣服。
  • P361+P364
  • P363 Wash contaminated clothing before reuse. 被污染的衣服洗净后方可重新使用。
  • P391 Collect spillage. Hazardous to the aquatic environment 收集对水环境有危害的泄漏物。
  • P403+P233
  • P405 Store locked up. 上锁保管。
  • P501 Dispose of contents/container to..… 处理内容物/容器.....
Hazard Class6.1
GHS Symbol
Warnings 危化品目录(2015) 危险化学品
TYPE OF TEST            : TD - Toxic dose (other than lowest)
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 104 gm/kg/99W-C
TOXIC EFFECTS :
   Tumorigenic - Carcinogenic by RTECS criteria
   Vascular - tumors
REFERENCE :
   NCITR* National Cancer Institute Carcinogenesis Technical Report Series.
   (Bethesda, MD)  No.0-205. For publisher information, see NTPTR*.
   Volume(issue)/page/year: NCI-TR-165,1979

TYPE OF TEST            : TD - Toxic dose (other than lowest)
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 216 gm/kg/78W-C
TOXIC EFFECTS :
   Tumorigenic - Carcinogenic by RTECS criteria
   Liver - tumors
REFERENCE :
   JEPTDQ Journal of Environmental Pathology and Toxicology.  (Park Forest
   South, IL)  V.1-5(3), 1977-81(?).  For publisher information, see JEPOEC.
   Volume(issue)/page/year: 2(2),325,1978

TYPE OF TEST            : TD - Toxic dose (other than lowest)
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 108 gm/kg/78W-C
TOXIC EFFECTS :
   Tumorigenic - Carcinogenic by RTECS criteria
   Vascular - tumors
REFERENCE :
   JEPTDQ Journal of Environmental Pathology and Toxicology.  (Park Forest
   South, IL)  V.1-5(3), 1977-81(?).  For publisher information, see JEPOEC.
   Volume(issue)/page/year: 2(2),325,1978

TYPE OF TEST            : TD - Toxi

TYPE OF TEST            : TD - Toxic dose (other than lowest)
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 97 gm/kg/78W-C
TOXIC EFFECTS :
   Tumorigenic - Carcinogenic by RTECS criteria
   Liver - tumors
REFERENCE :
   JEPTDQ Journal of Environmental Pathology and Toxicology.  (Park Forest
   South, IL)  V.1-5(3), 1977-81(?).  For publisher information, see JEPOEC.
   Volume(issue)/page/year: 2(2),325,1978

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 560 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   NCIBR* Progress Report for Contract No. NIH-NCI-E-68-1311, Submitted to the
   National Cancer Institute by Bio-Research Consultants, Inc. (9 Commercial
   Ave., Cambridge, MA 02141)  Volume(issue)/page/year: NCI-E-68-1311,1973

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 680 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   NCIBR* Progress Report for Contract No. NIH-NCI-E-68-1311, Submitted to the
   National Cancer Institute by Bio-Research Consultants, Inc. (9 Commercial
   Ave., Cambridge, MA 02141)  Volume(issue)/page/year: NCI-E-68-1311,1973

TYPE OF TEST            : Specific locus test
ROUTE OF EXPOSURE       : Oral
TEST SYSTEM             : Rodent - mouse
DOSE/DURATION           : 300 mg/kg/3D (Continuous)
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 135,219,1984

TYPE OF TEST            : DNA damage
TEST SYSTEM             : Rodent - hamster Lung
DOSE/DURATION           : 3 mmol/L
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 77,317,1980

TYPE OF TEST            : Mutation in microorganisms
TEST SYSTEM             : Bacteria - Salmonella typhimurium
DOSE/DURATION           : 1 umol/plate
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 77,317,1980

TYPE OF TEST            : Sister chromatid exchange
TEST SYSTEM             : Rodent - hamster Ovary
DOSE/DURATION           : 50 mg/L
REFERENCE :
   EMMUEG Environmental and Molecular Mutagenesis.  (Alan R. Liss, Inc., 41 E.
   11th St., New York, NY 10003)  V.10-    1987-  Volume(issue)/page/year:
   10(Suppl 10),1,1987

TYPE OF TEST            : Cytogenetic analysis
TEST SYSTEM             : Rodent - hamster Ovary
DOSE/DURATION           : 400 mg/L
REFERENCE :
   EMMUEG Environmental and Molecular Mutagenesis.  (Alan R. Liss, Inc., 41 E.
   11th St., New York, NY 10003)  V.10-    1987-  Volume(issue)/page/year:
   10(Suppl 10),1,1987

WGK Germany3
Safety Statements
  • S60 This material and its container must be disposed of as hazardous waste 该物质及其容器必须作为危险废物处置;
  • S61 Avoid release to the environment. Refer to special instructions/safety data sheet 避免释放到环境中,参考特别指示/安全收据说明书;
  • S45 In case of accident or if you feel unwell seek medical advice immediately (show the label where possible) 发生事故时或感觉不适时,立即求医(可能时出示标签);
  • S53 Avoid exposure - obtain special instructions before use 避免接触,使用前获得特别指示说明;
Hazard Codes T,N
Risk Statements
  • R68 Possible risk of irreversible effects 可能有不可挽回的作用的危险
  • R45 May cause cancer 可能致癌
  • R23/24/25 Toxic by inhalation, in contact with skin and if swallowed 吸入,皮肤接触及吞食都有毒
  • R50/53

其他信息

  • 4-氯-邻甲苯胺盐酸盐价格(试剂级):更新日期 产品编号 产品名称 包装 价格 2014/06/02 C0301 2-氨基-5-氯甲苯盐酸盐 4-Chloro-2-methylaniline Hydrochloride 500G 3730元 2014/06/02 C0301 2-氨基-5-氯甲苯盐酸盐 4-Chloro-2-methylaniline Hydrochloride 25G 493元
  • RTECS号:XU5250000
  • 色指数:37085
  • 图谱信息:4-氯-邻甲苯胺盐酸盐(3165-93-3)红外图谱(IR2) 4-氯-邻甲苯胺盐酸盐(3165-93-3)红外图谱(IR1)
  • 外观性质:白色或灰白色粉末。
  • MOL 文件:3165-93-3.mol
  • HazardClass:6.1(b)
  • PackingGroup:III

系列性分类


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