L-methionine sulfoxide L-蛋氨酸亚砜

CAS 3226-65-1 MFCD00063093

化学结构图

3226-65-1
SMILES: CS(=O)CC[C@H](N)C(=O)O

化学属性

Mol. FormulaC5H11NO3S
Mol. Weight165.21
TSCANo
Melting Point234-235°C
Boiling Point434.3°C at 760 mmHg
Flash Point216.4°C

别名和识别编码

Chemical NameL-Methionine Sulfoxide
CAS Number3226-65-1
Synonym L-Methionine sulfoxide {LY} L-Methionine sulfoxide methionine sulfoxide methionine sulfoxide, (+-)-isomer methionine sulfoxide, (2R)-isomer methionine sulfoxide, (2S)-isomer methionine sulfoxide, (R-(R*,S*))-isomer methionine sulfoxide, (S-(R*,S*))-isomer methionine sulfoxide, 35S-labeled, (+-)-isomer {} {LY} L-Methionine sulfoxide {} {} {} {LY} L-Methionine sulfoxide {} {} {} {} {LY} L-Methionine sulfoxide {} {} {} {} {} {LY} L-Methionine sulfoxide {} {} {} {} {} {} {LY} L-Methionine sulfoxide {} {} {} {} {} {} {} {LY} L-Methionine sulfoxide {} {} {} {} {} {} {} {} {LY} L-Methionine sulfoxide {} {} {} {} {} {} {} {} {} {LY} L-Methionine sulfoxide {} {} {} {} {} {} {} {} {} {} {LY} L-Methionine sulfoxide {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} L-Methionine sulfoxide {} {} {} {} {} {} {} {} {} {} {} {} {LY} L-Methionine sulfoxide {} {} {} {} {} {} {} {} {} {}
MDL NumberMFCD00063093
PubChem Substance ID158980
Beilstein Registry Number4129939
EC Number221-758-0
Chemical Name TranslationL-蛋氨酸亚砜
LabNetwork Molecule IDLN00199383
InChIInChI=1S/C5H11NO3S/c1-10(9)3-2-4(6)5(7)8/h4H,2-3,6H2,1H3,(H,7,8)/t4-,10?/m0/s1
Canonical SMILESO=C(O)[C@@H](N)CCS(C)=O
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分类

  • {SNA} Amino Acid Derivatives, Amino Acid Library, Amino Acids,
  • {SNA} Amino Acid Library Collection, Amino Acids, Amino Acids & Derivatives, Chemical Biology, Chemical Synthesis, I - Z, Metabolite Libraries and Collections, Methionine, Modified Amino Acids, Peptide Chemistry, 代谢组学,
  • {SN
  • {SNA} Amino Acid Derivatives, Amino Acid Library, Amino Acids, Chemical Biology, Chemical Synthesis, I - Z, Metabolic Libraries, Methionine, Modified Amino Acids, Peptide Chemistry, 代谢组学, 生化试剂, 细胞生物学

产品应用

  • An intermediate in the synthesis of the acyclic amino carboxylic acid L-Methionine sulfoximine.

相关文献及参考

  • Lee, B., et al.: J. Biol. Chem., 283, 28361 (2008),
  • Nordqvist, A., et al.: Bioorg. Med. Chem., 16, 5501 (2008),
  • [1]. Dos Santos LM, et al. Methionine and methionine sulfoxide treatment induces M1/classical macrophage polarization and modulates oxidative stress and purinergic signaling parameters. Mol Cell Biochem. 2017 Jan;424(1-2):69-78.

安全信息

WGK Germany3
GHS Symbol
Precautionary statements
  • P305+P351+P338
Hazard statements
  • H319 Causes serious eye irritation 严重刺激眼睛
Signal word Warning
Personal Protective Equipment Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
Safety Statements
  • S60 This material and its container must be disposed of as hazardous waste 该物质及其容器必须作为危险废物处置；
  • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后，立即用大量水冲洗并征求医生意见；
  • S37 Wear suitable gloves 戴适当手套；
Risk Statements
  • R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
Storage condition 2-8°C, sealed storage, away from moisture and light {LY} 2-8°C, sealed storage, away from moisture and light {} {LY} 2-8°C, sealed storage, away from moisture and light {} {} {LY} 2-8°C, sealed storage, away from moisture and light {} {} {} {LY} 2-8°C, sealed storage, away from moisture and light {} {} {} {} {LY} 2-8°C, sealed storage, away from moisture and light {} {} {} {} {} {LY} 2-8°C, sealed storage, away from moisture and light {} {} {} {} {} {} {LY} 2-8°C, sealed storage, away from moisture and light {} {} {} {} {} {} {} {LY} 2-8°C, sealed storage, away from moisture and light {} {} {} {} {} {} {} {} {LY} 2-8°C, sealed storage, away from moisture and light {} {} {} {} {} {} {} {} {} {LY} 2-8°C, sealed storage, away from moisture and light {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C, sealed storage, away from moisture and light {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C, sealed storage, away from moisture and light {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C

其他信息

  • Sigma Aldrich:3226-65-1(sigmaaldrich)
  • MOL 文件:3226-65-1.mol

系列性分类

  1. Life Science 生命科学
  2. Cell Biology 细胞生物学
  3. Bioactive Small Molecules - Cell Biology
  4. M - Bioactive Small Molecules
  1. Life Science 生命科学
  2. Metabolomics 代谢组学
  3. Metabolic Libraries - Metabolomics
  4. Amino Acid Library - Metabolic Libraries
  1. Medical Research Areas
  2. Metabolism
  3. Endogenous Metabolite  (内源性代谢物)

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