Isopropyl β-D-1-Thiogalactopyranoside 异丙基-β-D-1-硫代半乳糖吡喃糖苷
CAS 367-93-1 MFCD00063273
化学结构图
SMILES: CC(C)S[C@@H]1O[C@H](CO)[C@H](O)[C@H](O)[C@H]1O
化学属性
| Mol. Formula | C9H18O5S |
|---|---|
| Mol. Weight | 238 |
| Density | 1.37 |
| Melting Point | 113 |
| TSCA | Yes |
| Solubility | Soluble in water, and methanol |
| Stability | 对湿度和热敏感 |
别名和识别编码
| Chemical Name | Isopropyl β-D-1-Thiogalactopyranoside |
|---|---|
| Synonym | 1-ISOPROPYL-BETA-D-1-THIOGALACTO PYRANOSIDE 1-methylethyl1-thio-.beta.-D-Galactopyranoside IPTG 异丙基 β-D-硫代半乳糖苷 IPTG;异丙基-β-D-硫代半乳糖吡喃糖苷;异丙基-β-D-硫代半乳糖吡喃糖甙 IS ISOPROPYL-BETA-D-THI ISOPROPYL-BETA-D-THIOGALACTOPYRANOSIDE, DIOXANE FREE ISOPROPYLTHIO-B-THIOGALACTOPYRANOSIDE ISOPROPYLTHIO-BETA-THIOGALACTOSIDASE Isopropyl-β-D-thiogalactoside 异丙基-beta-D-硫代半乳糖吡喃糖甙 异丙基-beta-D-硫代半乳糖吡喃糖苷 异丙基-Β-D-硫代半乳糖苷(简称IPTG) 异丙基-β-D-硫代半乳糖吡喃糖苷; 异丙基-β-D-硫代半乳糖吡喃糖甙; 异丙基1-硫代-β-D-半乳糖吡喃糖苷; 异丙基-β-D-硫代半乳糖苷; 异丙基 β-D-1-硫代半乳糖吡喃糖苷; IPTG 异丙基-β-D-硫代半乳糖苷 |
| MDL Number | MFCD00063273 |
| PubChem Substance ID | 656894 |
| Beilstein Registry Number | 4631 |
| CAS Number | 367-93-1 |
| EC Number | 206-703-0 |
| Chemical Name Translation | 异丙基-β-D-1-硫代半乳糖吡喃糖苷 |
| Reaxys-RN | 4631 |
| Merck Number | 5082 |
| LabNetwork Molecule ID | LN00196082 |
| InChI | InChI=1S/C9H18O5S/c1-4(2)15-9-8(13)7(12)6(11)5(3-10)14-9/h4-13H,3H2,1-2H3/t5-,6+,7+,8-,9+/m1/s1 |
信息真实价格透明
资金保障
专业采购外包团队在线服务
信息真实价格透明
资金保障
专业采购外包团队在线服务
品牌质保精细包装
现货库存
一流品牌服务
分类
- {SNA} non-ionic
- {SNA} Core Bioreagents, Detergents A to M, Detergents by Applications, General Reagents, Life Science Reagents for Transfection, Membrane Protein Solubilization, Non-Ionic Detergents, Research Essentials, 去垢剂, 生化试剂
- {SNA} Carbohydrates, Carbohydrates A to Z, Carbohydrates H-L, Core Bioreagents, Detergents A to M, Detergents by Applications, General Reagents,
- {SNA} Core Bioreagents,
- {SNA} Carbohydrate
- {SNA} Core Bioreagents, Detergents A to M, Detergents by Applications, General Reagents, Life Science Reagents for Transfection, Membrane Protein Solubilization, Non-Ionic Detergents,
- {SNA} Carbohydrates,
产品应用
- IPTG 常用于需要诱导 β-半乳糖苷酶活性的克隆实验。它常与 X-Gal 或 Bluo-Gal 结合使用，用于重组细菌菌落的蓝白筛选，这些菌落可以诱导 lac 操纵子在大肠杆菌中的表达。IPTG 与 lacI 阻遏蛋白结合并改变其构象而发挥作用，防止 β-半乳糖苷酶编码基因 lacZ 的抑制。
相关文献及参考
- Merck: 14,5082 Beilstein: 17,IV,3726
安全信息
Personal Protective Equipment
Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
Eyeshields, Gloves, half-mask respirator (US), multi-purpose combination respirator cartridge (US)
WGK Germany3
GHS Symbol
Hazard Codes
Xn
Hazard statements
- H351 Suspected of causing cancer 怀疑致癌
- H319 Causes serious eye irritation 严重刺激眼睛
Precautionary statements
- P281 Use personal protective equipment as required. 使用所需的个人防护装备。
- P302+P340
- P305+P351+P338
- P312 Call a POISON CENTER or doctor/physician if you feel unwell. 如果你感觉不适，呼叫解毒中心或医生/医师。
Signal word
Warning
Safety Statements
- S22 Do not breathe dust 不要吸入粉尘；
- S23 Do not breathe gas/fumes/vapour/spray (appropriate wording to be specified by the manufacturer) 不要吸入气体/烟雾/蒸汽/喷雾；
- S24/25 Avoid contact with skin and eyes 避免皮肤和眼睛接触；
- S36/37 Wear suitable protective clothing and gloves 穿戴适当的防护服和手套；
Risk Statements
- R19 May form explosive peroxides 可能生成易爆的过氧化物质
- R40 Limited evidence of a carcinogenic effect 有限证据表明其致癌作用
- R66 Repeated exposure may cause skin dryness or cracking 反复接触可能导致皮肤干燥或皴裂
Storage condition
-20°C
储存温度2-8℃
储存温度：2-8°C; 充氩保存
其他信息
- Acros Organics:异丙基-beta-d-硫代乳吡喃糖苷(IPTG) Isopropyl-beta-D-thiogalactopyranoside, contains ca. 15% 1,4-Dioxane, for biochemistry, 99+%(367-93-1)
- MOL 文件:367-93-1.mol
- IPTG, Dioxane-Free (isopropyl-β-thiogalactoside) is an analogue of allolactose that binds specifically to the repressor protein of the lac operon and induces expression of β-galactosidase in Escherichia coli. The compound is widely used with X-Gal plates to screen for blue and white colonies. The lac operon system and IPTG have been used in multiple cloning experiments and cellular systems to study gene activity.
- Sigma Aldrich:367-93-1(sigmaaldrich)
- 存储注意事项:湿度敏感
- IPTG是β–半乳糖苷酶的活性诱导物质。基于这个特性，当pUC系列的载体DNA（或其他带有lacZ 基因载体DNA）以lacZ 缺失细胞为宿主进行转化时、或用M13噬菌体的载体DNA进行转染时，如果在平板培养基中加入X–gal和IPTG，由于β–半乳糖苷酶的α–互补性，可以根据是否呈现白色菌落（或噬菌斑）而方便地挑选出基因重组体。此外，它还可以作为具有lac或tac等启动子的表达载体的表达诱导物使用。
- 用途一:常用分子生物学试剂，常用于蓝白斑筛选及IPTG诱导的细菌内的蛋白表达等。
- MSDS 信息:IPTG(367-93-1).msds
- 图谱信息:异丙基-beta-D-硫代半乳糖吡喃糖苷(367-93-1)红外图谱(IR1) 异丙基-beta-D-硫代半乳糖吡喃糖苷(367-93-1)质谱(MS)
- 异丙基-beta-D-硫代半乳糖吡喃糖苷价格(试剂级):更新日期 产品编号 产品名称 包装 价格 2014/06/02 I0328 异丙基1-硫代-β-D-半乳糖吡喃糖苷 Isopropyl 1-Thio-beta-D-galactopyranoside 1G 378元 2014/06/02 I0328 异丙基1-硫代-β-D-半乳糖吡喃糖苷 Isopropyl 1-Thio-beta-D-galactopyranoside 5G 1100元 2010/06/21 228565000 异丙基-beta-D-硫代半乳糖吡喃糖苷 Isopropyl-beta-D-thiogalactopyranoside 99+%, for biochemistry, contains ca. 15% 1,4-Dioxane 500 MG 639元
- F:10
- 外观性质:白色粉末。易溶于水、甲醇、乙醇，可溶于丙酮、氯仿，不溶于乙醚。是β-半乳糖苷酶和β-半乳糖透酶的诱导剂，不被β-半乳糖苷水解，是硫代半乳糖转酰酶的底物熔点:109.5～110.5℃
- Alfa Aesar:异丙基-β-D-硫代半乳糖苷,dioxane-free,99% Isopropyl-beta-D-thiogalactoside, dioxane-free, 99%(367-93-1)
- 易溶于水、甲醇、乙醇，可溶于丙酮、氯仿，不溶于乙醚。是β-半乳糖苷酶和β-半乳糖透酶的诱导剂，不被β-半乳糖苷水解，是硫代半乳糖转酰酶的底物
- 比旋光度:-31 ° (c=1, water)
- TCI Shanghai:异丙基-1-硫代-β-D-半乳糖吡喃糖苷 Isopropyl 1-Thio-beta-D-galactopyranoside,>;98.0%(GC)(367-93-1)
京ICP备2020036287号