rel-(2R,3S)-1,4-Dimercapto-2,3-butanediol 二硫赤藓醇

CAS 6892-68-8 MFCD00063750

化学结构图

6892-68-8
SMILES: O[C@H](CS)[C@@H](O)CS

化学属性

Mol. FormulaC4H10O2S2
Mol. Weight154.25
Melting Point82-84 °C
TSCAYes
Density1.302
SolubilitySoluble in water (50 mg/ml), and methanol.
Stability对湿度敏感
Boiling Point247.65 °C at 760 mmHg

别名和识别编码

Chemical Namerel-(2R,3S)-1,4-Dimercapto-2,3-butanediol
Synonym DTE {LY} DTE {} {LY} DTE {} {} {LY} DTE {} {} {} {LY} DTE {} {} {} {} {LY} DTE {} {} {} {} {} {LY} DTE {} {} {} {} {} {} {LY} DTE {} {} {} {} {} {} {} {LY} DTE {} {} {} {} {} {} {} {} {LY} DTE {} {} {} {} {} {} {} {} {} {LY} DTE {} {} {} {} {} {} {} {} {} {} {LY} DTE {} {} {} {} {} {} {} {} {} {} {} {LY} DTE {} {} {} {} {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {} {} {} {} {LY} DTE {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} DTE {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} DTE {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} DTE {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} DTE {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} DTE {} {} {} {} {} {} {} {} {} {}
CAS Number6892-68-8
PubChem Substance ID87567840
EC Number229-998-8
Beilstein Registry Number2(3)2360
MDL NumberMFCD00063750
Reaxys-RN1719756
Chemical Name Translation二硫赤藓醇
InChIKeyVHJLVAABSRFDPM-ZXZARUISSA-N
LabNetwork Molecule IDLN01342900
InChIInChI=1S/C4H10O2S2/c5-3(1-7)4(6)2-8/h3-8H,1-2H2/t3-,4+
Canonical SMILESO[C@H]([C@H](O)CS)CS
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分类

  • {SNA} Carbohydrates A to Z, Carbohydrates D-F, Disulfide Bridge Cleavage Reagents, Monosaccharide, Reducing Agents, SDS-PAGE, 分子生物学, 变性剂, 生化试剂, 碳水化合物, 蛋白电泳, 蛋白质组学
  • {SNA} Biochemicals, Biochemicals and Reagents, Denaturation, Disulfide Bridge Cleavage Reagents, 分子生物学, 分子生物学试剂
  • {SNA} Disulfide Bridge Cleavage Reagents, Reducing Agents, SDS-PAGE, 分子生物学, 变性剂, 生化试剂, 蛋白电泳, 蛋白质组学
  • {SNA} Alphabet

产品应用

  • 生化研究中还原巯基或二硫键的试剂。

相关文献及参考

  • Protective agent for preventing oxidation of thiol groups and reagent for reduction of disulfide groups in proteins: Biochemistry, 3, 480 (1964); 11, 2939 (1972); J. Biol. Chem., 243, 716 (1968); compare 1,4-Dithio-DL-threitol, A15797.
  • Beilstein:2(3)2360

安全信息

GHS Symbol
WGK Germany3
Hazard statements
  • H315 Causes skin irritation 会刺激皮肤
  • H319 Causes serious eye irritation 严重刺激眼睛
  • H335 May cause respiratory irritation 可能导致呼吸道刺激
  • H302+H312+H332
Personal Protective Equipment dust mask type N95 (US), Eyeshields, Gloves
Hazard Codes Xn Xi
RTECSKF2410000
Precautionary statements
  • P271 Use only outdoors or in a well-ventilated area.? 只能在室外或通风良好的地方使用。
  • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P305+P351+P338
  • P332+P313
  • P501 Dispose of contents/container to..… 处理内容物/容器.....
  • P301+P312+P330
  • P302+P350
  • P337+P313
  • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
  • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
  • P302+P352+P312+P362+P364
  • P270 Do not eat, drink or smoke when using this product. 使用本产品时不要吃东西，喝水或吸烟。
  • P304+P340+P312
  • P312 Call a POISON CENTER or doctor/physician if you feel unwell. 如果你感觉不适，呼叫解毒中心或医生/医师。
  • P305+P351+P338+P337+P313
  • P305+
Signal word Warning {} {} {} {} {} {TCI}
Storage condition 2-8°C {LY} 2-8°C Air Sensitive {} {LY} 2-8°C {} {} {LY} 2-8°C {} {} {} {LY} 2-8°C {} {} {} {} {LY} 2-8°C {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {
Safety Statements
  • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后，立即用大量水冲洗并征求医生意见；
  • S37 Wear suitable gloves 戴适当手套；
  • S36 Wear suitable protective clothing 穿戴适当的防护服；
  • S60 This material and its container must be disposed of as hazardous waste 该物质及其容器必须作为危险废物处置；
  • S36/37/39 Wear suitable protective clothing, gloves and eye/face protection 穿戴适当的防护服、手套和眼睛/面保护；
  • S37/39 Wear suitable gloves and eye/face protection 穿戴适当的手套和眼睛/面保护；
Risk Statements
  • R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
  • R22 Harmful if swallowed 吞咽有害
UN Number UN3335 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intramuscular
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 309 mg/kg
TOXIC EFFECTS :
   Behavioral - convulsions or effect on seizure threshold
REFERENCE :
   JPPMAB Journal of Pharmacy and Pharmacology.  (Pharmaceutical Soc. of Great
   Britain, 1 Lambeth High St., London SEI 7JN, UK)  V.1-    1949-
   Volume(issue)/page/year: 1,576,1949

TYPE OF TEST            : Cytogenetic analysis
TEST SYSTEM             : Human Lymphocyte
DOSE/DURATION           : 100 umol/L
REFERENCE :
   HEREAY Hereditas (Lund, Sweden).  (Gjoerloffsgatan 121, S-261 34 Landskrona,
   Sweden)  V.1-    1947-  Volume(issue)/page/year: 91,105,1979

其他信息

  • Sigma Aldrich:6892-68-8(sigmaaldrich)
  • 图谱信息:二硫代赤藓醇(6892-68-8)质谱(MS) 二硫代赤藓醇(6892-68-8)核磁图( 13 CNMR) 二硫代赤藓醇(6892-68-8)红外图谱(IR1) 二硫代赤藓醇(6892-68-8)红外图谱(IR2) 二硫代赤藓醇(6892-68-8)核磁图( 1 HNMR)
  • TCI Shanghai:1,4-二硫代赤藓醇 Dithioerythritol,>;98.0%(GC)(T)(6892-68-8)
  • 敏感性:Air Sensitive
  • 易溶于水。
  • Alfa Aesar:1,4-二硫代赤藻糖醇,99% 1,4-Dithioerythritol, 99%(6892-68-8)
  • 用途一:生化研究中还原巯基或二硫键的试剂。
  • 外观性质:白色结晶。易溶于水熔点：82-86℃
  • F:3-10-13-23
  • Acros Organics:二硫代赤藓醇 Dithioerythritol, 95%(6892-68-8)
  • MOL 文件:6892-68-8.mol
  • Dithioerythritol is an epimer of dithiothreitol and an erythro isomer of 2,3-dihydroxy-1,4- dithiolbutane. The compound is a protective agent for thiol groups and strong reducing agent that is capable of reducing disulfide bonds.
  • 二硫代赤藓醇价格(试剂级):更新日期 产品编号 产品名称 包装 价格 2011/08/23 63002580 二硫赤色草醇（+4℃） 500mg 112.2元 2011/04/16 D1320 二硫赤藓醇 Dithioerythritol 25G 3280元 2011/04/16 D1320 二硫赤藓醇 Dithioerythritol 5G 880元

系列性分类

  1. Life Science 生命科学
  2. Biochemicals and Reagents 生化试剂
  3. Denaturation - Biochemicals and Reagents
  1. Life Science 生命科学
  2. Biochemicals and Reagents 生化试剂
  3. Carbohydrates - Biochemicals and Reagents
  4. BioUltra - Carbohydrates
  1. Life Science 生命科学
  2. Biochemicals and Reagents 生化试剂
  3. Denaturation - Biochemicals and Reagents
  4. Disulfide Bridge Cleavage Reagents - Denaturation
  1. Life Science 生命科学
  2. Molecular Biology 分子生物学
  3. Molecular Biology Reagents - Molecular Biology
  4. Biochemicals - Molecular Biology Reagents
  1. Life Science 生命科学
  2. Molecular Biology 分子生物学
  3. Molecular Biology Reagents - Molecular Biology
  4. Biochemicals - Molecular Biology Reagents
  1. Life Science 生命科学
  2. Proteomics 蛋白质组学
  3. Native Protein Sample Preparation - Proteomics
  4. Cell Lysis and Protein Extraction Reagents - Native Protein Sample Preparation
  5. Chemical Modification Reagents - Cell Lysis and Protein Extraction Reagents
  1. Life Science 生命科学
  2. Proteomics 蛋白质组学
  3. Protein Electrophoresis - Proteomics
  4. SDS-PAGE - Protein Electrophoresis
  5. Reducing Agents - SDS-PAGE
  1. Life Science 生命科学
  2. Proteomics 蛋白质组学
  3. Protein Electrophoresis - Proteomics
  4. SDS-PAGE - Protein Electrophoresis
  5. Urea - SDS-PAGE
  1. Functional Group 官能团索引
  2. alkylthiol
  1. Life Science 生命科学
  2. Biochemicals and Reagents
  3. Carbohydrates
  4. Disaccharide
  1. Life Science 生命科学
  2. Biochemicals and Reagents
  3. Denaturation
  4. Acids and Bases
  1. Life Science 生命科学
  2. Biochemicals and Reagents
  3. Denaturation
  4. Detergents
  1. Life Science 生命科学
  2. Biochemicals and Reagents
  3. Fluorescent Probes, Labels, Particles and Stains
  4. Functional Group Reactive Labels
  5. Functional Group Reactive Labels for Spectroscopy
  1. Life Science 生命科学
  2. Biochemicals and Reagents
  3. Proteomics
  4. Native Protein Sample Preparation
  5. Cell Lysis and Protein Extraction Reagents
  1. Life Science 生命科学
  2. Biochemicals and Reagents
  3. Molecular Biology
  4. Protein Electrophoresis
  5. SDS-PAGE
  6. Gel Loading Reagents
  1. Life Science 生命科学
  2. Biochemicals and Reagents
  3. Proteomics
  4. Protein Electrophoresis
  5. SDS-PAGE
  6. Gel Loading Reagents
  1. Life Science 生命科学
  2. Biochemicals and Reagents
  3. Plant Biotechnology
  4. Plant Proteomics
  5. Protein Electrophoresis
  6. SDS-PAGE
  7. Gel Loading Reagents