D-Camphor D-樟脑

CAS 464-49-3 MFCD00064149

化学结构图

464-49-3
SMILES: CC1(C)[C@@H]2CC[C@@]1(C)C(=O)C2

化学属性

Mol. FormulaC10H16O
Mol. Weight152
Melting Point179-181
Density5.24
Flash Point65°(149°F)
TSCAYes
Boiling Point204°C(lit.)
Autoignition Point870 °F
Vapor Density5.24 (vs air)
Vapor Pressure4 mmHg ( 70 °C)
Refractive index44.5 ° (C=20, EtOH)
SolubilitySoluble in ethanol (5%),

别名和识别编码

Chemical NameD-Camphor
MDL NumberMFCD00064149
CAS Number464-49-3
Synonym (+)-2-Bornanone (+)-Camphor (+)-樟脑 (1R)-1,7,7-三甲基二环[2.2.1]庚烷-2-酮 (1R)-(+)-樟脑 (1R)-1,7,7-三甲基二环[2.2.1]庚烷-2-酮 2-莰酮,天然樟脑 7,7-trimethyl-(1r)-bicyclo(2.2.1)heptan-2-on Alcanfor Bicyclo(2.2.1)heptan-2-one, 1,7,7-trimethyl-, (1R)- CAMPHOR Camphor USP Camphor, (+)- D(+)-CAMPHOR D(+)-樟脑(天然) D(-)-CAMPHOR D-(+)-Camphor D-2-Bornanone D-2-CAMPHANONE D-2-KETO-1,7,7-TRIMETHYLNORCAMPHANE D-Camphor FEMA 2230 Japanese camphor bicyclo[2.2.1]heptan-2-one,1,7,7-trimethyl-,(1R)- camphora d-2-Bornanone Α-莰酮 右旋樟脑(天然樟脑) 樟腦
PubChem Substance ID159055
EC Number207-355-2
Beilstein Registry Number2042745
Merck Number1732
Chemical Name TranslationD-樟脑
Reaxys-RN1907611
Wiswesser Line NotationL55 A CVTJ A1 A1 B1
LabNetwork Molecule IDLN00241548
InChIInChI=1S/C10H16O/c1-9(2)7-4-5-10(9,3)8(11)6-7/h7H,4-6H2,1-3H3/t7-,10+/m1/s1
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分类

  • {SNA} Analytical Standard
  • {SNA} Asymmetric Synthesis, Chemical Synthesis, Chiral Building Blocks, Ketones, Organic Building Blocks
  • {SNA} A-F,
  • {SNA} A-F, All Alphabetically Sorted, Alphabetical Index of Analytical Standards, Analytical Standards, Analytical/Chromatography, Basil, C, CA - CG, Camphor, Chromatography, Cinnamon, Flavors and Fragrances, Food & Beverage Standards, Food Products & Beverages, Fragrance Allergens in Cosmetic Products, Herbs & Spices, Laurel, Lavender, Rosemary, Substance Classification, Terpene

产品应用

  • 手性中间体和助剂

相关文献及参考

  • Merck: 14,1732 Beilstein:7(3)400
  • Merck: 14,1732

安全信息

GHS Symbol
WGK Germany1
Hazard statements
  • H226 Flammable liquid and vapour 易燃液体和蒸气
  • H228 Flammable solid 易燃固体
  • H302 Harmful if swallowed 吞食有害
  • H304 May be fatal if swallowed and enters airways 吞食和进入呼吸道可能致命
  • H312 Harmful in contact with skin 皮肤接触有害
  • H315 Causes skin irritation 会刺激皮肤
  • H317 May cause an allergic skin reaction 可能导致皮肤过敏
  • H319 Causes serious eye irritation 严重刺激眼睛
  • H330 Fatal if inhaled 吸入致命
  • H332 Harmful if inhaled 吸入有害
  • H335 May cause respiratory irritation 可能导致呼吸道刺激
  • H341 Suspected of causing genetic defects 怀疑导致遗传性缺陷
  • H371 May cause damage to organs 可能导致器官损伤
  • H400 Verytoxictoaquaticlife 对水生生物毒性非常大。
  • H410 Verytoxictoaquaticlifewithlonglastingeffects 对水生生物毒性非常大并具有长期影响。
Personal Protective Equipment Eyeshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges dust mask type N95 (US), Eyeshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges
RTECSEX1260000
Precautionary statements
  • P203
  • P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking. 远离热源/火花/明火/热的表面。——禁止吸烟。
  • P233 Keep container tightly closed. ?保持容器密闭。
  • P240 Ground/bond container and receiving equipment. 与地面接触/连接集装箱和接受设备。
  • P241 Use explosion-proof electrical/ventilating/lighting/…/equipment. 使用防爆电气/通风/照明/ .../设备。
  • P242 Use only non-sparking tools. 只能使用无火花工具。
  • P243 Take precautionary measures against static discharge. 采取预防措施,防止静电放电。
  • P260 Do not breathe dust/fume/gas/mist/vapours/spray. 不要吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
  • P264+P265
  • P270 Do not eat, drink or smoke when using this product. 使用本产品时不要吃东西,喝水或吸烟。
  • P271 Use only outdoors or in a well-ventilated area.? 只能在室外或通风良好的地方使用。
  • P272 Contaminated work clothing should not be allowed out of the workplace. 污染的工作服不得带出工作场所。
  • P273 Avoid release to the environment. 避免释放到环境中。
  • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
  • P281 Use personal protective equipment as required. 使用所需的个人防护装备。
  • P284 Wear respiratory protection.? 佩戴呼吸保护装置。
  • P301+P310
  • P301+P312
  • P301+P312+P330
  • P301+P316
  • P301+P317
  • P302+P352
  • P303+P361+P353
  • P304+P312
  • P304+P340
  • P305+P351+P338
  • P305+P351+P338+P337+P313
  • P308+P316
  • P309+P311
  • P310 Immediately call a POISON CENTER or doctor/physician. 立即呼救解毒中心或医生/医师。
  • P312 Call a POISON CENTER or doctor/physician if you feel unwell. 如果你感觉不适,呼叫解毒中心或医生/医师。
  • P316
  • P317
  • P318
  • P319
  • P320 Specific treatment is urgent (see … on this label). 紧急具体治疗(见本标签上的)。
  • P321 Specific treatment (see … on this label). 具体治疗(见本标签上的)。
  • P322 Specific measures (see …on this label). 具体治疗(见本标签上的)。
  • P330 Rinse mouth. 漱口
  • P331 Do NOT induce vomiting.. 不要催吐。
  • P332+P313
  • P332+P317
  • P333+P313
  • P333+P317
  • P337+P313
  • P337+P317
  • P362 Take off contaminated clothing and wash before reuse. 脱掉污染的衣服,清洗后方可重新使用
  • P362+P364
  • P363 Wash contaminated clothing before reuse. 被污染的衣服洗净后方可重新使用。
  • P370+P378
  • P391 Collect spillage. Hazardous to the aquatic environment 收集对水环境有危害的泄漏物。
  • P403+P233
  • P403+P235
Signal word Warning
Safety Statements
  • S16 Keep away from sources of ignition - No smoking 远离火源,禁止吸烟;
  • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后,立即用大量水冲洗并征求医生意见;
  • S36 Wear suitable protective clothing 穿戴适当的防护服;
Packing GroupIII
UN Number 2717 UN 2717 4.1/PG 3 UN2717
Risk Statements
  • R11 Highly flammable 非常易燃
  • R20/21/22 Harmful by inhalation, in contact with skin and if swallowed 吸入、皮肤接触和不慎吞咽有害
  • R22 Harmful if swallowed 吞咽有害
  • R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
Hazard Codes 4.1 F,Xn
Hazard Class4.1
TYPE OF TEST            : LD90 - Lethal Dose
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 525 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   FCTXAV Food and Cosmetics Toxicology.  (London, UK)  V.1-19, 1963-81.  For
   publisher information, see FCTOD7.  Volume(issue)/page/year: 16,665,1978

TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 3500 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   FCTXAV Food and Cosmetics Toxicology.  (London, UK)  V.1-19, 1963-81.  For
   publisher information, see FCTOD7.  Volume(issue)/page/year: 16,665,1978

TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Mammal - cat
DOSE/DURATION           : 400 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   FCTXAV Food and Cosmetics Toxicology.  (London, UK)  V.1-19, 1963-81.  For
   publisher information, see FCTOD7.  Volume(issue)/page/year: 16,665,1978

TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 2200 mg/kg
TOXIC EFFECTS :
   Behavioral - convulsions or effect on seizure threshold
REFERENCE :
   FCTXAV Food and Cosmetics Toxicology.  (London, UK)  V.1-19, 1963-81.  For
   publisher information, see FCTOD7.  Volume(issue)/page/year: 16,665,1978

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 1310 mg/kg
TOXIC EFFECTS :
   Details o

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 4 gm/kg
SEX/DURATION            : female 6-15 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Maternal Effects - other effects
REFERENCE :
   NTIS** National Technical Information Service.  (Springfield, VA 22161)
   Formerly U.S. Clearinghouse for Scientific & Technical Information.
   Volume(issue)/page/year: PB92-170034

其他信息

  • 食品添加剂最大允许使用量最大允许残留量标准:添加剂中文名称 允许使用该种添加剂的食品中文名称 添加剂功能 最大允许使用量(g/kg) 最大允许残留量(g/kg) d-樟脑 食品 食品用香料 用于配制香精的各香料成分不得超过在GB 2760中的最大允许使用量和最大允许残留量
  • Sigma Aldrich:464-49-3(sigmaaldrich)
  • D-樟脑价格(试剂级):更新日期 产品编号 产品名称 包装 价格 2014/06/02 C0010 (+)-樟脑 (+)-Camphor 500G 649元 2014/06/02 C0010 (+)-樟脑 (+)-Camphor 25G 117元 2010/06/21 227841000 D-樟脑 D(+)-Camphor 97% 100 GR 374元
  • 蒸气压:4 mm Hg ( 70 °C)
  • 类别:易燃固体
  • 可燃性危险特性:遇明火, 高温, 氧化剂可燃烧; 受热分解辛辣刺激烟雾
  • 溶解度: 1 G/800ML 水(25°C) 1g溶于1 ML 乙醇, 1 ML 乙醚, 0.5 ML 氯仿, 0.4 ML 苯, 0.4 ML 丙酮, 1.5 ML 松节油, 0.5 ML 冰醋酸. 溶于苯胺、硝基苯、二硫化碳、四氢萘、十氢萘和石油醚。
  • 毒性分级:中毒
  • 爆炸物危险特性:蒸汽遇明火, 高温, 氧化剂可爆炸
  • Acros Organics:D(+)-樟脑 D(+)-Camphor, 97%(464-49-3)
  • 储运特性:库房低温通风干燥; 与氧化剂分开存放; 防明火, 高温
  • 下游产品:(R)-(+)-降冰片胺 --> 三3-(三氟甲基羟基亚甲基)-D-樟脑 铕 --> 3-三氟乙酰基-D-樟脑 --> 降龙涎香醚
  • 蒸气密度:5.24 (vs air)
  • 灭火剂:水雾, 二氧化碳, 干粉, 泡沫
  • TCI Shanghai:(+)-樟脑 (+)-Camphor,>;98.0%(GC)(464-49-3)
  • 急性毒性:腹腔-大鼠 LD50: 3500 毫克/公斤; 口服-小鼠 LD50: 1310 毫克/公斤
  • FEMA:2230
  • 刺激数据:皮肤-兔 500 毫克/24小时 轻度
  • Alfa Aesar:(1R)-(+)-樟脑,98% (1R)-(+)-Camphor, 98%(464-49-3)
  • 图谱信息:D-樟脑(464-49-3)红外图谱(IR1) D-樟脑(464-49-3)红外图谱(IR2) D-樟脑(464-49-3)核磁图( 13 CNMR) D-樟脑(464-49-3)质谱(MS)
  • MOL 文件:464-49-3.mol

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