L-Dithiothreitol L-二硫苏糖醇

CAS 16096-97-2 MFCD00064305

化学结构图

16096-97-2
SMILES: O[C@@H](CS)[C@@H](O)CS |&1:1,4|

化学属性

Mol. FormulaC4H10O2S2
Mol. Weight154.24
Melting Point48.0 to 53.0 deg-C

别名和识别编码

Chemical NameL-Dithiothreitol
Synonym (-)-Cleland’s Reagent (-)-Cleland’s Reagent (2R,3R)-1,4-Dimercapto-2,3-butanediol L-DTT Cleland reagent chiral (2R,3R)-1,4-Dimercapto-2,3-butanediol Cleland reagent chiral L-(-)-Dithiothreitol L-1,4-Dithiothreitol L-DTT L-Dtt L-threo-1,4-Dimercapto-2,3-butanediol
PubChem Substance ID87568072
EC Number240-263-0
Beilstein Registry Number2036371
MDL NumberMFCD00064305
CAS Number16096-97-2
Chemical Name TranslationL-二硫苏糖醇
Reaxys-RN2036371
Wiswesser Line NotationSH1YQYQ1SH -L,THREO
InChIKeyVHJLVAABSRFDPM-QWWZWVQMSA-N
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分类

  • {SNA} Carbohydrates A to Z, Carbohydrates D-F, Monosaccharide, 生化试剂, 碳水化合物
  • {SNA} Biochemicals and Reagents, Carbohydrates, Carbohydrates A to Z, Carbohydrates D-F, Monosaccharide

安全信息

GHS Symbol
WGK Germany3
Hazard statements
  • H315 Causes skin irritation 会刺激皮肤
  • H335 May cause respiratory irritation 可能导致呼吸道刺激
  • H302 Harmful if swallowed 吞食有害
  • H312 Harmful in contact with skin 皮肤接触有害
  • H319 Causes serious eye irritation 严重刺激眼睛
Personal Protective Equipment dust mask type N95 (US), Eyeshields, Gloves
RTECSEK1612000
Precautionary statements
  • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
  • P362 Take off contaminated clothing and wash before reuse. 脱掉污染的衣服，清洗后方可重新使用
  • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
  • P332+P313
  • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P305+P351+P338
  • P302+P350
  • P337+P313
  • P305+P351+P338+P337+P313
  • P302+P352+P332+P313+P362+P364
Signal word Warning
Hazard Codes Xn
Risk Statements
  • R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
  • R21/22 Harmful in contact with skin and if swallowed 皮肤接触和不慎吞咽有害
Safety Statements
  • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后，立即用大量水冲洗并征求医生意见；
  • S36/37 Wear suitable protective clothing and gloves 穿戴适当的防护服和手套；
Storage condition <;0 <0°C 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 179 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JMCMAR Journal of Medicinal Chemistry.  (American Chemical Soc.,
   Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC
   20037)  V.6-    1963-  Volume(issue)/page/year: 15,600,1972

系列性分类

  1. Chemical Synthesis 化学合成
  2. Asymmetric Synthesis 不对称合成
  3. Chiral Building Blocks 手性分子砌块

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