4-Nitro-2,3-Lutidine-N-Oxide 2,3-二甲基-4-硝基吡啶-N-氧化物

CAS 37699-43-7 MFCD00065172

化学结构图

37699-43-7
SMILES: CC1=C(C=C[N+]([O-])=C1C)[N+]([O-])=O

化学属性

Mol. FormulaC7H8N2O3
Mol. Weight168.15
Melting Point94-98 °C
TSCANo
Appearance 淡黄色粉末,易溶于氯仿,微溶于乙醇。熔点:89.0~92.0℃。
Boiling Point297.07 °C at 760 mmHg

别名和识别编码

Chemical Name4-Nitro-2,3-Lutidine-N-Oxide
CAS Number37699-43-7
Synonym 2,3-Dimethyl-4-nitropyridine 1-oxide {LY} 2,3-Dimethyl-4-nitropyridine 1-oxide {} {LY} 2,3-Dimethyl-4-nitropyridine 1-oxide {} {} {LY} 2,3-Dimethyl-4-nitropyridine 1-oxide {} {} {} {LY} 2,3-Dimethyl-4-nitropyridine 1-oxide {} {} {} {} {LY} 2,3-Dimethyl-4-nitropyridine 1-oxide {} {} {} {} {} {LY} 2,3-Dimethyl-4-nitropyridine 1-oxide {} {} {} {} {} {} {LY} 2,3-Dimethyl-4-nitropyridine 1-oxide {} {} {} {} {} {} {} {LY} 2,3-Dimethyl-4-nitropyridine 1-oxide {} {} {} {} {} {} {} {} {LY} 2,3-Dimethyl-4-nitropyridine 1-oxide {} {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {} {LY} 2,3-Dimethyl-4-nitropyridine 1-oxide {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2,3-Dimethyl-4-nitropyridine 1-oxide {} {} {} {} {} {} {} {} {} {} {} {LY} 2,3-Dimethyl-4-nitropyridine 1-oxide {} {} {} {} {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2,3-Dimethyl-4-nitropyridine 1-oxide {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2,3-Dimethyl-4-nit
MDL NumberMFCD00065172
Beilstein Registry Number1569438
PubChem Substance ID87569273
Reaxys-RN1569438
Chemical Name Translation2,3-二甲基-4-硝基吡啶-N-氧化物
InChIKeyCFMTVTYBZMKULI-UHFFFAOYSA-N
Wiswesser Line NotationT6NJ AO B1 C1 DNW
Canonical SMILESO=[N+](C1=CC=[N+]([O-])C(C)=C1C)[O-]
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分类

  • Nitric Oxide Reagents
  • Mutagenesis Research Chemicals
  • Heterocycles
  • {SNA} Building Blocks, C7, Chemical Synthesis, Heterocyclic Building Blocks, Pyridines

产品应用

  • Nitropyridine oxide derivative

相关文献及参考

  • Nagao, M., et al.: Cancer Res., 32, 2369 (1972),

安全信息

RTECSUT2807000
Safety Statements
  • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后,立即用大量水冲洗并征求医生意见;
  • S36 Wear suitable protective clothing 穿戴适当的防护服;
Risk Statements
  • R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
WGK Germany3
GHS Symbol
Precautionary statements
  • P201 Obtain special instructions before use. 使用前获取专门指示。
  • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
  • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
  • P305+P351+P338
  • P305+P351+P338+P337+P313
  • P308+P313
  • P332+P313
  • P362 Take off contaminated clothing and wash before reuse. 脱掉污染的衣服,清洗后方可重新使用
  • P405 Store locked up. 上锁保管。
  • P501 Dispose of contents/container to..… 处理内容物/容器.....
Hazard statements
  • H315 Causes skin irritation 会刺激皮肤
  • H319 Causes serious eye irritation 严重刺激眼睛
  • H335 May cause respiratory irritation 可能导致呼吸道刺激
Signal word Warning
Personal Protective Equipment dust mask type N95 (US), Eyeshields, Gloves
Hazard Codes Xi
Packing GroupIII
Hazard Class6.1
UN Number 2811
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 1760 mg/kg/15W-I
TOXIC EFFECTS :
   Tumorigenic - equivocal tumorigenic agent by RTECS criteria
   Tumorigenic - tumors at site of application
REFERENCE :
   GANNA2 Gann.  Japanese Journal of Cancer Research.  (Tokyo, Japan)  V.1-75,
   1907-84.  For publisher information, see JJCREP.  Volume(issue)/page/year:
   70,799,1979

TYPE OF TEST            : Mutation in microorganisms
TEST SYSTEM             : Bacteria - Salmonella typhimurium
DOSE/DURATION           : 50 nmol/plate
REFERENCE :
   GANNA2 Gann.  Japanese Journal of Cancer Research.  (Tokyo, Japan)  V.1-75,
   1907-84.  For publisher information, see JJCREP.  Volume(issue)/page/year:
   70,799,1979

TYPE OF TEST            : Mutation in microorganisms
TEST SYSTEM             : Bacteria - Escherichia coli
DOSE/DURATION           : 500 umol/L
REFERENCE :
   GANNA2 Gann.  Japanese Journal of Cancer Research.  (Tokyo, Japan)  V.1-75,
   1907-84.  For publisher information, see JJCREP.  Volume(issue)/page/year:
   70,799,1979

TYPE OF TEST            : DNA repair
TEST SYSTEM             : Bacteria - Escherichia coli
DOSE/DURATION           : 500 ug/well
REFERENCE :
   CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut
   Sts., Philadelphia, PA 19106)  V.1-    1941-  Volume(issue)/page/year:
   32,2369,1972

TYPE OF TEST            : DNA damage
TEST SYSTEM             : Rodent - mouse Fibroblast
DOSE/DURATION           : 500 umol/L
REFERENCE :
   CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut
   Sts., Philadelphia, PA 19106)  V.1-    1941-  Volume(issue)/page/year:
   35,521,1975

TYPE OF TEST            : DNA repair
TEST SYSTEM             : Bacteria - Bacillus subtilis
DOSE/DURATION           : 500 ug/well
REFERENCE :
   CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut
   Sts., Philadelphia, PA 19106)  V.1-    1941-  Volume(issue)/page/year:
   32,2369,1972

TYPE OF TEST            : DNA repair
TEST SYSTEM             : Yeast - Saccharomyces cerevisiae
DOSE/DURATION           : 500 ug/well
REFERENCE :
   CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut
   Sts., Philadelphia, PA 19106)  V.1-    1941-  Volume(issue)/page/year:

Storage condition -20°C {LY} -20°C {} {LY} -20°C {} {} {LY} -20°C {} {} {} {LY} -20°C {} {} {} {} {LY} -20°C {} {} {} {} {} {LY} -20°C {} {} {} {} {} {} {LY} -20°C {} {} {} {} {} {} {} {LY} -20°C {} {} {} {} {} {} {} {} {LY} -20°C {} {} {} {} {} {} {} {} {} {LY} -20°C {} {} {} {} {} {} {} {} {} {} {LY} -20°C {} {} {} {} {} {} {} {} {} {} {} {LY} -20°C {} {} {} {} {} {} {} {} {} {} {} {} {LY} -20°C {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} -20°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} -20°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} -20°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} -20°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} -20°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} -20°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} -20°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {

其他信息

  • 用途一:用作药物兰索拉唑中间体
  • MOL 文件:37699-43-7.mol
  • 存储注意事项:湿度敏感
  • Sigma Aldrich:37699-43-7(sigmaaldrich)
  • 上游原料:氢氧化钠 --> 硫酸 --> 乙酸 --> 硝酸 --> 过氧化氢 --> 2,3-二甲基吡啶
  • TCI Shanghai:2,3-二甲基-4-硝基吡啶-N-氧化物 2,3-Dimethyl-4-nitropyridine N-Oxide,>;98.0%(T)(37699-43-7)
  • Alfa Aesar:2,3-二甲基-4-硝基吡啶N-氧化物,97% 2,3-Dimethyl-4-nitropyridine N-oxide, 97%(37699-43-7)
  • 2,3-二甲基-4-硝基吡啶-N-氧化物价格(试剂级):更新日期 产品编号 产品名称 包装 价格 2014/06/02 D2905 2,3-二甲基-4-硝基吡啶N-氧化物 2,3-Dimethyl-4-nitropyridine N-Oxide 5G 707元 2014/06/02 D2905 2,3-二甲基-4-硝基吡啶N-氧化物 2,3-Dimethyl-4-nitropyridine N-Oxide 25G 2260元 2010/05/25 L19457 2,3-二甲基-4-硝基吡啶 N-氧化物, 97% 2,3-Dimethyl-4-nitropyridine N-oxide, 97% 25g 3864元
  • MSDS 信息:4-Nitro-2,3-lutidine-N-oxide(37699-43-7).msds

系列性分类


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