Tunicamycin 衣霉素

CAS 11089-65-9 MFCD00065709

化学结构图

11089-65-9
SMILES: CC(=O)N[C@@H]1[C@@H](O[C@@H](CO)[C@H](O)[C@H]1O)O[C@@H]1O[C@H](C[C@@H](O)[C@H]2O[C@H]([C@H](O)[C@@H]2O)N2C=CC(=O)NC2=O)[C@H](O)[C@H](O)[C@H]1NC(=O)/C=C/CCCCCCCCC(C)C

化学属性

Mol. Formula(CH2)nC29H44N4O16
Mol. Weight817
TSCANo

别名和识别编码

Chemical NameTunicamycin
Beilstein Registry Number6888090
PubChem Substance ID24900473
MDL NumberMFCD00065709
Synonym Tunicamycin from Streptomyces sp. 来源于链霉菌 属
CAS Number11089-65-9
Merck Number14,9819
Chemical Name Translation衣霉素
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分类

  • {SA} AIDS and Viral Research Reagents, Antibacterial, Antibiotics, Antibiotics A to Z, Antibiotics T-Z, Antibiotics by Application, Antifungal, Antineoplastic and Immunosuppressive Antibiotics, Antiviral, Bioactive Small Molecules, Cell Biology, Cell Signaling and Neuroscience, Chemical Activators and Inhibitors of ER Stress, Chemical Structure Class, Endoplasmic Reticulum Stress, Glycobiology, Immune Cell Signaling and Blood, Immune System Regulation, Inhibitors, Inhibitors and Substrates, Interferes with Protein Synthesis, L - Z, Mechanism of Action, Nucleosides,
  • {SNA} Anti

安全信息

RTECSYO7980200
Personal Protective Equipment Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges
GHS Symbol
Precautionary statements
  • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
  • P301+P310
Hazard statements
  • H300 Fatal if swallowed 吞食致命
WGK Germany3
Signal word Danger
Hazard Codes 6.1 T+
Safety Statements
  • S28 After contact with skin, wash immediately with plenty of ... (to be specified by the manufacturer) 皮肤接触后，立即用大量…（由生产厂家指定）冲洗；
  • S37/39 Wear suitable gloves and eye/face protection 穿戴适当的手套和眼睛/面保护；
  • S45 In case of accident or if you feel unwell seek medical advice immediately (show the label where possible) 发生事故时或感觉不适时，立即求医（可能时出示标签）；
Risk Statements
  • R26/28 Very toxic by inhalation and if swallowed 吸入及吞食都有剧毒
  • R28 Very toxic if swallowed 吞咽极毒
  • R33 Danger of cumulative effects 有累积作用的危险
Packing GroupII
UN Number 3462 UN3462
Storage condition Moisture & Light Sensitive 
TYPE OF TEST            : DNA inhibition
TEST SYSTEM             : Rodent - mouse Cells - not otherwise specified
DOSE/DURATION           : 4 ug/L
REFERENCE :
   JANTAJ Journal of Antibiotics.  (Japan Antibiotics Research Assoc., 2-20-8
   Kamiosaki, Shinagawa-ku, Tokyo, 141, Japan)  V.2-5, 1948-52;  V.21- 1968-
   Volume(issue)/page/year: 39,1148,1986

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Parenteral
SPECIES OBSERVED        : Rodent - mouse
DOSE                    : 500 ug/kg
SEX/DURATION            : female 6 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Fertility - abortion
REFERENCE :
   TJADAB Teratology, The International Journal of Abnormal Development. (Alan
   R. Liss, Inc., 41 E. 11th St., New York, NY 10003)  V.1-    1968-
   Volume(issue)/page/year: 28,13A,1983

系列性分类

  1. Life Science 生命科学
  2. Antibiotics 抗生素
  3. Antibiotics A to Z - Antibiotics
  4. Antibiotics T-Z - Antibiotics A to Z
  1. Life Science 生命科学
  2. Antibiotics 抗生素
  3. Antibiotics by Application - Antibiotics
  4. Antineoplastic and Immunosuppressive Antibiotics - Antibiotics by Application
  1. Life Science 生命科学
  2. Antibiotics 抗生素
  3. Spectrum of Activity - Antibiotics
  4. Antibacterial - Spectrum of Activity
  5. L - Z - Antibacterial
  1. Life Science 生命科学
  2. Cell Biology 细胞生物学
  3. Cell Signaling and Neuroscience - Cell Biology
  4. Immune Cell Signaling and Blood - Cell Signaling and Neuroscience
  5. Immune System Regulation - Immune Cell Signaling and Blood
  6. AIDS and Viral Research Reagents - Immune System Regulation

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