cis-8,11,14-Eicosatrienoic Acid 顺式-8,11,14-二十碳三烯酸

CAS 1783-84-2 MFCD00065721

化学结构图

1783-84-2
SMILES: CCCCC/C=C\C/C=C\C/C=C\CCCCCCC(=O)O

化学属性

Mol. FormulaC20H34O2
Mol. Weight306.48
Refractive index1.4760 to 1.4800
Boiling Point200 °C at 760 mmHg
Flash Point62°C(lit.)

别名和识别编码

Chemical Namecis-8,11,14-Eicosatrienoic Acid
CAS Number1783-84-2
Synonym Dihomo-γ-linolenic acid {LY} Dihomo-γ-linolenic acid {} {LY} Dihomo-γ-linolenic acid {} {} {LY} Dihomo-γ-linolenic acid {} {} {} {LY} Dihomo-γ-linolenic acid {} {} {} {} {LY} Dihomo-γ-linolenic acid {} {} {} {} {} {LY} Dihomo-γ-linolenic acid {} {} {} {} {} {} {LY} Dihomo-γ-linolenic acid {} {} {} {} {} {} {} {LY} Dihomo-γ-linolenic acid {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Dihomo-γ-linolenic acid {} {} {} {} {} {} {} {} {} {LY} Dihomo-γ-linolenic acid {} {} {} {} {} {} {} {} {} {} {LY} Dihomo-γ-linolenic acid {} {} {} {} {} {} {} {} {} {} {} {LY} Dihomo-γ-linolenic acid {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Dihomo-γ-linolenic acid {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Dihomo-γ-linolenic acid {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Dihomo-γ-linolenic acid {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Dihomo-γ-linolenic acid
MDL NumberMFCD00065721
PubChem Substance ID5280581
Beilstein Registry Number2(3)1521
EC Number217-233-0
Chemical Name Translation顺式-8,11,14-二十碳三烯酸
Reaxys-RN1913514
LabNetwork Molecule IDLN01303724
InChIInChI=1S/C20H34O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20(21)22/h6-7,9-10,12-13H,2-5,8,11,14-19H2,1H3,(H,21,22)/b7-6-,10-9-,13-12-
Canonical SMILESCCCCC/C=C\C/C=C\C/C=C\CCCCCCC(O)=O
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分类

  • {SNA} Biochemicals and Reagents, Cell Biology, Fatty Acid Metabolism, Fatty Acids and conjugates, Fatty Acyls, Lipids, Metabolic Pathways, Metabolomics, Omega 6 fatty acids and derivatives, Polyunsaturated, Unsaturated Fatty Acids and Derivatives
  • {SNA} Fatty Acids and conjugates,
  • {SNA} Fatty Acids and conjugates, Fatty Acyls, Omega 6 fatty acids and derivatives,
  • Glycerols
  • Fatty Acid Derivatives & Lipids
  • {SNA} Biochemicals and Reagents, Fatty Acid Metabolism, Fatty Acids and conjugates, Fatty Acyls, Lipids, Metabolic Pathways, Metabolomics, Omega 6 fatty acids and derivatives, Polyunsaturated, Unsaturated Fatty Acids and Derivatives
  • {SNA} Fatty Acids and

产品应用

  • cis-8,11,14-Eicosatrienoic acid is a fatty acid which has selective tumoricidal action.

相关文献及参考

  • [2]. Gallagher H, et al. Dihomo-γ-linolenic acid inhibits several key cellular processes associated with atherosclerosis. Biochim Biophys Acta Mol Basis Dis. 2019 Sep 1;1865(9):2538-2550.
  • [3]. Yang X, et al. Dihomo-γ-linolenic acid inhibits growth of xenograft tumors in mice bearing human pancreatic cancer cells (BxPC-3) transfected with delta-5-desaturase shRNA. Redox Biol. 2019 Jan;20:236-246.
  • Das, U., et al.: Cancer Lett., 56, 235 (1991),
  • Menendez, J., et al.: Breast Cancer Res. Treat., 72, 203 (2002),
  • Rudra, P., et al.: Anticancer Res., 21, 29 (2001),
  • [1]. Wang X, et al. Multiple roles of dihomo-γ-linolenic acid against proliferation diseases. Lipids Health Dis. 2012 Feb 14;11:25.
  • [1]. Wang X, et al. Multiple roles of dihomo-γ-linolenic acid against proliferation diseases. Lipids Health Dis. 2012 Feb 14;11:25.
  • [2]. Gallagher H, et al. Dihomo-γ-linolenic acid inhibits several key cellular processes associated with ather

安全信息

WGK Germany3
Personal Protective Equipment Eyeshields, Gloves, half-mask respirator (US), multi-purpose combination respirator cartridge (US)
RTECSJX3880000
Signal word
Precautionary statements
  • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
  • P501 Dispose of contents/container to..… 处理内容物/容器.....
  • P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking. 远离热源/火花/明火/热的表面。——禁止吸烟。
  • P403+P235
Storage condition Solution, -20°C, 2 years {LY} Solution, -20°C, 2 years {} {LY} Solution, -20°C, 2 years {} {} {LY} Solution, -20°C, 2 years {} {} {} {LY} Solution, -20°C, 2 years {} {} {} {} {LY} Solution, -20°C, 2 years {} {} {} {} {} {LY} Solution, -20°C, 2 years {} {} {} {} {} {} {LY} Solution, -20°C, 2 years {} {} {} {} {} {} {} {LY} Solution, -20°C, 2 years {} {} {} {} {} {} {} {} {LY} Solution, -20°C, 2 years {} {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {} {LY} Solution, -20°C, 2 years {} {} {} {} {} {} {} {} {} {} {LY} Solution, -20°C, 2 years {} {} {} {} {} {} {} {} {} {} {} {LY} Solution, -20°C, 2 years {} {} {} {} {} {} {} {} {} {} {} {} {LY} Solution, -20°C, 2 years {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Solution, -20°C, 2 years {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Solution, -20°C, 2 years {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Solution, -20°C, 2 years {} {} {} {} {} {} {} {} {} {} {} {} {}
Hazard statements
  • H227 Combustible liquid 可燃液体

系列性分类

  1. Life Science 生命科学
  2. Metabolomics 代谢组学
  3. Metabolic Pathways - Metabolomics
  4. Fatty Acid Metabolism - Metabolic Pathways
  1. Life Science 生命科学
  2. Biochemicals and Reagents 生化试剂
  3. Lipids - Biochemicals and Reagents
  4. Fatty Acyls - Lipids
  5. Fatty Acids and conjugates - Fatty Acyls
  6. Unsaturated Fatty Acids and Derivatives - Fatty Acids and conjugates
  7. Polyunsaturated - Unsaturated Fatty Acids and Derivatives
  8. Omega 6 fatty acids and derivatives - Polyunsaturated
  1. Medical Research Areas
  2. Metabolism
  3. Endogenous Metabolite  (内源性代谢物)

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