N-Boc-L-prolinol N-Boc-L-脯氨醇

CAS 69610-40-8 MFCD00066232

化学结构图

69610-40-8
SMILES: CC(C)(C)OC(=O)N1CCC[C@@H]1CO

化学属性

Mol. FormulaC10H19NO3
Mol. Weight201.26
Melting Point60-64°C
TSCANo
Density1.084
Boiling Point289.5°C at 760 mmHg

别名和识别编码

Chemical NameN-Boc-L-prolinol
CAS Number69610-40-8
Alfabeta NameBOCPROLINOL NL---
MDL NumberMFCD00066232
Synonym 1-Boc-2-(S)-pyrrolidinemethanol {LY} 1-Boc-2-(S)-pyrrolidinemethanol {} {LY} 1-Boc-2-(S)-pyrrolidinemethanol {} {} {LY} 1-Boc-2-(S)-pyrrolidinemethanol {} {} {} {LY} 1-Boc-2-(S)-pyrrolidinemethanol {} {} {} {} {LY} 1-Boc-2-(S)-pyrrolidinemethanol {} {} {} {} {} {LY} 1-Boc-2-(S)-pyrrolidinemethanol {} {} {} {} {} {} {LY} 1-Boc-2-(S)-pyrrolidinemethanol {} {} {} {} {} {} {} {LY} 1-Boc-2-(S)-pyrrolidinemethanol {} {} {} {} {} {} {} {} {LY} 1-Boc-2-(S)-pyrrolidinemethanol {} {} {} {} {} {} {} {} {} {LY} 1-Boc-2-(S)-pyrrolidinemethanol {} {} {} {} {} {} {} {} {} {} {LY} 1-Boc-2-(S)-pyrrolidinemethanol {} {} {} {} {} {} {} {} {} {} {} {LY} 1-Boc-2-(S)-pyrrolidinemethanol {} {} {} {} {} {} {} {} {} {} {} {} {LY} 1-Boc-2-(S)-pyrrolidinemethanol {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 1-Boc-2-(S)-pyrrolidinemethanol {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 1-Boc-2-(S)-pyrrolidinemethanol {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 1-Boc-2-(S)-pyrrolidineme
PubChem Substance ID643448
Beilstein Registry Number3542667
Reaxys-RN3542667
EC Number250-023-7
Chemical Name TranslationN-Boc-L-脯氨醇
LabNetwork Molecule IDLN00008076
InChIInChI=1S/C10H19NO3/c1-10(2,3)14-9(13)11-6-4-5-8(11)7-12/h8,12H,4-7H2,1-3H3/t8-/m0/s1
Canonical SMILESO=C(N1[C@@H](CCC1)CO)OC(C)(C)C
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分类

  • {SNA} Amino Acid Derivatives, Amino Alcohols, Chemical Biology, Chemical Synthesis, Peptide Chemistry
  • {SNA} Amino Acids & Derivatives, Amino Alcohols, Chemical Biology, Chemical Synthesis, Peptide Chemistry

产品应用

  • 用于合成抗凝血剂(anticoagulants)
  • 新烟碱乙酰胆碱受体合成砌块。用于合成手性β-氨基硫化物和β-氨基酸硫醇

相关文献及参考

  • 1. Lin. N.-H. et al. J. Med. Chem. 40 , 385, (1997) 摘要
  • 2. Elliott, R.L. et al. Bioorg. Med. Chem. Lett. 6 , 2283, (1996)
  • 3. Abreo, M.A. et al. J. Med. Chem. 39 , 817, (1996) 摘要
  • 4. Cran, G.A. et al. Tetrahedron Asymmetry 6 , 1553, (1995)
  • Bioorg. Med. Chem. 12 , 2099-2114, (2004) 摘要
  • FT-IR 2 (1), 1302:A

安全信息

Warnings IRRITANT
WGK Germany3
GHS Symbol
Precautionary statements
  • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
  • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
  • P302+P352+P332+P313+P362+P364
  • P305+P351+P338
  • P305+P351+P338+P337+P313
  • P332+P313
  • P362 Take off contaminated clothing and wash before reuse. 脱掉污染的衣服,清洗后方可重新使用
Hazard statements
  • H315 Causes skin irritation 会刺激皮肤
  • H319 Causes serious eye irritation 严重刺激眼睛
  • H335 May cause respiratory irritation 可能导致呼吸道刺激
Hazard Codes Xi
Personal Protective Equipment dust mask type N95 (US), Eyeshields, Gloves
Signal word Warning
Safety Statements
  • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后,立即用大量水冲洗并征求医生意见;
  • S36 Wear suitable protective clothing 穿戴适当的防护服;
  • S36/37/39 Wear suitable protective clothing, gloves and eye/face protection 穿戴适当的防护服、手套和眼睛/面保护;
Risk Statements
  • R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
Storage condition 2-8°C {LY} 2-8°C Store at room temperature {} {LY} 2-8°C {} {} {LY} 2-8°C {} {} {} {LY} 2-8°C {} {} {} {} {LY} 2-8°C {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°

其他信息

  • 不溶于水。

系列性分类


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