Sulfacetamide 乙酰磺胺

CAS 144-80-9 MFCD00066501

化学结构图

144-80-9
SMILES: CC(=O)NS(=O)(=O)c1ccc(N)cc1

化学属性

Mol. FormulaC8H10N2O3S
Mol. Weight214.24
Melting Point182-184°C
TSCAYes
Solubility<0.01 G/100 ML AT 16 ºC
Appearance 白色结晶粉末,熔点179-184℃。溶于乙醇,微溶于水或乙醚,几乎不溶于氯仿或苯,溶于稀矿酸或氢氧化碱溶液。无臭,有特殊酸味。
Density1.373
Boiling Point239.433°C at 760 mmHg
Flash Point107.073°C

别名和识别编码

Chemical NameSulfacetamide
CAS Number144-80-9
Alfabeta NameACETYLAMINOBENZENESULFONAMIDE N4---
MDL NumberMFCD00066501
Synonym Sulfacetamide {LY} Sulfacetamide {} {LY} Sulfacetamide {} {} {LY} Sulfacetamide {} {} {} {LY} Sulfacetamide {} {} {} {} {LY} Sulfacetamide {} {} {} {} {} {LY} Sulfacetamide {} {} {} {} {} {} {LY} Sulfacetamide {} {} {} {} {} {} {} {LY} Sulfacetamide {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {LY} Sulfacetamide {} {} {} {} {} {} {} {} {} {LY} Sulfacetamide {} {} {} {} {} {} {} {} {} {} {LY} Sulfacetamide {} {} {} {} {} {} {} {} {} {} {} {LY} Sulfacetamide {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Sulfacetamide {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Sulfacetamide {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Sulfacetamide {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Sulfacetamide {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Sulfacetamide
PubChem Substance ID5320
Beilstein Registry Number981718
EC Number205-640-6
Merck Number8899
Chemical Name Translation乙酰磺胺
Reaxys-RN981718
Wiswesser Line NotationZR DSWMV1
LabNetwork Molecule IDLN00132407
InChIInChI=1S/C8H10N2O3S/c1-6(11)10-14(12,13)8-4-2-7(9)3-5-8/h2-5H,9H2,1H3,(H,10,11)
Canonical SMILESCC(NS(=O)(C1=CC=C(N)C=C1)=O)=O
信息真实价格透明    资金保障    专业采购外包团队在线服务   
信息真实价格透明    资金保障    专业采购外包团队在线服务   
品牌质保精细包装    现货库存    一流品牌服务   

分类

  • {SNA} Alphabetical Index of Analytical Standards, Analytical Standards, Analytical/Chromatography, Antibiotics, Antibiotics A to Z, Antibiotics N-S, Bacteriostatic, Biochemicals and Reagents, Chemical Structure, Chromatography, Clinical Standards, Principle, S, SN - SZ, Sulfonamides
  • {SNA} Antibiotics, Antibiotics A to Z, Antibiotics N-S, Building Blocks,
  • {SNA} Antibiotics, Antibiotics A to Z, Antibiotics N-S, Biochemicals and Reagents, Chemical Structure Class, Sulfonamides
  • {SNA} Antibiotics A to Z, Antibiotics N-S,
  • {SNA} Antibiotics A to Z

产品应用

  • 医药,用于治疗结膜炎,砂眼及其他眼部感染。

相关文献及参考

  • Short: III/20a
  • Short: EINECS
  • Merck: 14,8899 Beilstein:14(4)2662
  • Merck: 14,8899

安全信息

Warnings IRRITANT
WGK Germany2
RTECSAC8450000
Personal Protective Equipment Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
Safety Statements
  • S36/37 Wear suitable protective clothing and gloves 穿戴适当的防护服和手套;
Risk Statements
  • R68 Possible risk of irreversible effects 可能有不可挽回的作用的危险
Packing GroupIII
Hazard Codes Xi
Hazard Class6.1(b)
Storage condition 2-8°C, protect from light {LY} 2-8°C, protect from light {} {LY} 2-8°C, protect from light {} {} {LY} 2-8°C, protect from light {} {} {} {LY} 2-8°C, protect from light {} {} {} {} {LY} 2-8°C, protect from light {} {} {} {} {} {LY} 2-8°C, protect from light {} {} {} {} {} {} {LY} 2-8°C, protect from light {} {} {} {} {} {} {} {LY} 2-8°C, protect from light {} {} {} {} {} {} {} {} {LY} 2-8°C, protect from light {} {} {} {} {} {} {} {} {} {LY} 2-8°C, protect from light {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C, protect from light {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C, protect from light {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C, protect from light {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C, protect from light {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C, protect from light {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C, protect from light {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {}
UN Number 3249
GHS Symbol
Precautionary statements
  • P201 Obtain special instructions before use. 使用前获取专门指示。
  • P202 Do not handle until all safety precautions have been read and understood. 已阅读并理解所有的安全预防措施之前,切勿操作。
  • P281 Use personal protective equipment as required. 使用所需的个人防护装备。
  • P308+P313
  • P405 Store locked up. 上锁保管。
  • P501a
Signal word Warning
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 6600 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   AEPPAE Naunyn-Schmiedeberg's Archiv fuer Experimentelle Pathologie und
   Pharmakologie.  (Berlin, Ger.) V.110-253, 1925-66.  For publisher
   information, see NSAPCC.  Volume(issue)/page/year: 211,367,1950

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 606 mg/kg
TOXIC EFFECTS :
   Behavioral - altered sleep time (including change in righting reflex)
REFERENCE :
   FRZKAP Farmatsevtichnii Zhurnal (Kiev).  (V/O Mezhdunarodnaya Kniga, 113095
   Moscow, USSR) V.3-    1930-  Volume(issue)/page/year: (6),26,1987

TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 5 gm/kg
TOXIC EFFECTS :
   Behavioral - rigidity (including catalepsy)
   Lungs, Thorax, or Respiration - dyspnea
   Gastrointestinal - hypermotility, diarrhea
REFERENCE :
   JOURAA Journal of Urology.  (Williams & Wilkins Co., 428 E. Preston St.,
   Baltimore, MD  21202) V.1-    1917-  Volume(issue)/page/year: 47,183,1942

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 16500 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JOURAA Journal of Urology.  (Williams & Wilkins Co., 428 E. Preston St.,
   Baltimore, MD  21202) V.1-    1917-  Volume(issue)/page/year: 47,183,1942

TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF E

TYPE OF TEST            : Sex chromosome loss and nondisjunction
TEST SYSTEM             : Mold - Neurospora crassa
DOSE/DURATION           : 250 mg/L
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 167,35,1986

TYPE OF TEST            : Sex chromosome loss and nondisjunction
TEST SYSTEM             : Yeast - Saccharomyces cerevisiae
DOSE/DURATION           : 2 gm/L
REFERENCE :
   EVHPAZ EHP, Environmental Health Perspectives.  (U.S. Government Printing
   Office, Supt of Documents, Washington, DC 20402)  No.1-    1972-
   Volume(issue)/page/year: 31,97,1979

TYPE OF TEST            : Sister chromatid exchange
TEST SYSTEM             : Rodent - hamster Ovary
DOSE/DURATION           : 1 gm/L
REFERENCE :
   EMMUEG Environmental and Molecular Mutagenesis.  (Alan R. Liss, Inc., 41 E.
   11th St., New York, NY 10003)  V.10-    1987-  Volume(issue)/page/year:
   10(Suppl 10),1,1987

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 10 gm/kg
SEX/DURATION            : female 10 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Effects on Embryo or Fetus - fetal death
REFERENCE :
   PROEAS Problemy Endokrinologii.  Problems of Endocrinology.  (V/O
   Mezhdunarodnaya Kniga, 113095 Moscow, USSR)  V.1-6, 1936-41; 13-    1967-
   Volume(issue)/page/year: 14,89,1968

其他信息

  • Sigma Aldrich:144-80-9(sigmaaldrich)
  • 方法一:磺胺醋酰钠酸化而得,将磺胺醋酸钠溶解于水中,用5%盐酸调节至pH3.8-4,析出磺胺醋酰。过滤,水洗,干燥得成品。
  • 溶于乙醇,微溶于水或乙醚,几乎不溶于氯仿或苯,溶于稀矿酸或氢氧化碱溶液。无臭,有特殊酸味。
  • MOL 文件:144-80-9.mol
  • 用途一:医药,用于治疗结膜炎,砂眼及其他眼部感染。
  • MSDS 信息:N-((4-Aminophenyl)sulfonyl)acetamide(144-80-9).msds
  • 上游原料:磺胺乙酰钠 --> 磺胺醋酸钠
  • 图谱信息:磺胺醋酰(144-80-9)质谱(MS) 磺胺醋酰(144-80-9)红外图谱(IR1) 磺胺醋酰(144-80-9)红外图谱(IR2)
  • Alfa Aesar:磺胺醋酰,98% Sulfacetamide, 98%(144-80-9)
  • 磺胺醋酰价格(试剂级):更新日期 产品编号 产品名称 包装 价格 2010/05/25 A19836 磺胺醋酰, 98% Sulfacetamide, 98% 50g 403元 2010/05/25 A19836 磺胺醋酰, 98% Sulfacetamide, 98% 250g 893元

系列性分类


相关产品推荐