Adenosine, N-(1-methyl-2-phenylethyl)-, (R)-

CAS 38594-96-6 MFCD00069194

化学结构图

38594-96-6
SMILES: C[C@H](CC1C=CC=CC=1)NC1=NC=NC2=C1N=CN2[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O

化学属性

Mol. FormulaC19H23N5O4
Mol. Weight385.42

别名和识别编码

Chemical Name(-)-N6-(2-Phenylisopropyl)adenosine
Synonym (-)-N6-(2-Phenylisopropyl)adenosine (R)-N6-(1-Methyl-2-phenylethyl)adenosine (R)-N6-(1-Methyl-2-phenylethyl)adenosine N6-(L-2-Phenylisopropyl)adenosine R-(-)-PIA L-Pia N(sup 6)-(L-Phenylisopropyl)adenosine N6-(L-2-Phenylisopropyl)adenosine R-(-)-PIA Th 162 l-N(sup 6)-Phenylisopropyladenosine l-Phenylisopropyladenosine
MDL NumberMFCD00069194
PubChem Substance ID24277681
CAS Number38594-96-6
EC Number254-028-5
Beilstein Registry Number4912716
Chemical Name Translation
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分类

  • {SNA} Adenosines/P2 Nucleotide Receptor - Agonists, Adenosines/P2 Nucleotide Receptors (Purinergics), Agonists, Bioactive Small Molecule Alphabetical Index, GPCR Modulators, GPCR Proteins, Modulators and Antibodies, Membrane Protein Biology Tools, Neuroscience, Neurotransmission, Neurotransmitters, P-PH, 生化试剂, 生物活性小分子, 细胞信号转导和神经科学, 细胞生物学, 蛋白质及衍生物
  • {SNA} Adenosines/P2 Nucleotide Receptor - Agonists, Adenosines/P2 Nucleotide Receptors (Purinergics), Agonists, Bioactive Small Molecules, Biochemicals and Reagents, Cell Biology, Cell Signaling and Neuroscience,

相关文献及参考

  • Daly, J.W. J. Med. Chem. 25 , 197, (1982) 摘要
  • Bruns, et al. Mol. Pharmacol. 29 , 331, (1986) 摘要
  • Tan HL, et al. Cardiovasc. Drugs Ther. 13 , 441, (1999) 摘要

安全信息

WGK Germany3
Personal Protective Equipment Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
RTECSAU7404930 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE                    : 770 ug/kg
SEX/DURATION            : female 11-12 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Effects on Embryo or Fetus - fetal death
REFERENCE :
   TJADAB Teratology, The International Journal of Abnormal Development. (Alan
   R. Liss, Inc., 41 E. 11th St., New York, NY 10003)  V.1-    1968-
   Volume(issue)/page/year: 25(2),35A,1982

系列性分类

  1. Life Science 生命科学
  2. Cell Biology 细胞生物学
  3. Cell Signaling and Neuroscience - Cell Biology
  4. Neuroscience - Cell Signaling and Neuroscience
  5. Neurotransmission - Neuroscience
  6. Neurotransmitters - Neurotransmission
  7. Adenosines/P2 Nucleotide Receptors (Purinergics) - Neurotransmitters
  8. Agonists - Adenosines/P2 Nucleotide Receptors (Purinergics)

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