Normorphine

CAS 466-97-7 MFCD00069318

化学结构图

466-97-7
SMILES: Oc1ccc2c3c1O[C@H]1[C@@H](O)C=C[C@H]4[C@@H](C2)NCC[C@]314

化学属性

Mol. FormulaC16H17NO3
Mol. Weight271.34

别名和识别编码

Chemical NameMorphinan-3,6-alpha-diol,7,8-didehydro-4,5-alpha-epoxy-
CAS Number466-97-7
Synonym N-Normorphine Demethylmorphine Normorphine NSC 270042 (5?,6?)-7,8-Didehydro-4,5-epoxy-morphinan-3,6-diol Desmethylmorphine 4,5-Epoxy-3,6-dihydromorphin-7-ene N-Demethylmorphine (-)-Normorphine
MDL NumberMFCD00069318
PubChem Substance ID24897470
EC Number207-381-4
Beilstein Registry Number5297209
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分类

  • Metabolites & Impurities
  • Pharmaceuticals
  • Intermediates & Fine Chemicals,
  • {SNA} Alkaloids, Alphabetic, Analytical Standards, Analytical/Chromatography, Chemical Structure, Chromatography, Drugs & Metabolites, Drugs of Abuse, Forensic and Veterinary Standards, Morphine, N, NJ - NZ, Neat Compounds

产品应用

  • Normorphine is a metabolite of Morphine (M652290).

相关文献及参考

  • Coffman, B., et al.: Drug Metab. Dispos., 25, 1 (1997),
  • Hanks, G., et al.: Br. J. Cancer, 84, 587 (2001),
  • Projean, D., et al.: Xenobiotica, 33, 841 (2003),

安全信息

WGK Germany3
GHS Symbol
Precautionary statements
  • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
  • P260 Do not breathe dust/fume/gas/mist/vapours/spray. 不要吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P284 Wear respiratory protection.? 佩戴呼吸保护装置。
  • P302+P350
  • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
  • P310 Immediately call a POISON CENTER or doctor/physician. 立即呼救解毒中心或医生/医师。
Hazard statements
  • H330 Fatal if inhaled 吸入致命
  • H310 Fatal in contact with skin 皮肤接触致命
  • H300 Fatal if swallowed 吞食致命
RTECSQC7814000
Signal word Danger
Personal Protective Equipment Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 104 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   BJPCAL British Journal of Pharmacology and Chemotherapy.  (London, UK)
   V.1-33, 1946-68.  For publisher information, see BJPCBM.
   Volume(issue)/page/year: 17,433,1961

Restrict 精麻类化学品

系列性分类

  1. Analytical & Chromatography 分析化学与色谱
  2. Analytical Standards
  3. Alphabetic - Analytical Standards
  4. N - Alphabetic
  5. NJ - NZ - N

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