Quisqualic acid 使君子氨酸

CAS 52809-07-1 MFCD00069337

化学结构图

52809-07-1
SMILES: N[C@@H](CN1OC(=O)NC1=O)C(O)=O

化学属性

Mol. FormulaC5H7N3O5
Mol. Weight189
TSCANo
Melting Point185-187°

别名和识别编码

Chemical NameQuisqualic acid
CAS Number52809-07-1
Synonym L-Quisqualic Acid 使君子氨酸 3-(3,5-Dioxo-1,2,4-oxadiazolidin-2-yl)-L-alanine β-(3,5-二氧代-1,2,4-氧杂重氮烷-2-基)-L-丙氨酸 beta-(3,5-Dioxo-1,2,4-oxadiazolidin-2-yl)-L-alanine L-(+)-?-Amino-3,5-dioxo-1,2,4-oxadiazolidine-2-propanoic Acid β-(3,5-Dioxo-1,2,4-oxadiazolidin-2-yl)-L-alanine 3-(3,5-Dioxo-1,2,4-oxadiazolidin-2-yl)-L-alanine
MDL NumberMFCD00069337
PubChem Substance ID24278004
Beilstein Registry Number1078734
Merck Number14,8085
Chemical Name Translation使君子氨酸
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分类

  • {SNA} AMPA/Kainate Agonists, Excitatory Amino Acids, Ion Channels, Ionotropic Glutamate Receptor Modulators, Ligand-Gated Ion Channels, Neuroscience, Neurotransmission, Neurotransmitters, 细胞信号转导和神经科学, 细胞生物学
  • {SNA} AMPA/Kainate Agonists, Bioactive Small Molecules, Cell Biology, Cell Signaling and Neuroscience, Excitatory Amino Acids, Ion Channels, Ionotropic Glutamate Receptor Modulators, Ligand-Gated Ion Channels, Neuroscience, Neurotransmission, Neurotransmitters, Q
  • Amino Acids & Derivatives; Heterocycles
  • Neurochemicals

产品应用

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相关文献及参考

  • [2]. H Bräuner-Osborne, et al. Ligands for Glutamate Receptors: Design and Therapeutic Prospects. J Med Chem. 2000 Jul 13;43(14):2609-45.
  • Honore, T., et al.: J. Neurochem., 38, 173 (1982),
  • Recasens, M., et al.: Neurochem. Int., 13, 463 (1988),
  • Schoepp, D., et al.: J. Neurochem., 50, 1605 (1988),
  • [1]. Hugues-Olivier Bertrand, et al. Common and Selective Molecular Determinants Involved in Metabotopic Glutamate Receptor Agonist Activity. J Med Chem. 2002 Jul 18;45(15):3171-83.
  • [1]. Hugues-Olivier Bertrand, et al. Common and Selective Molecular Determinants Involved in Metabotopic Glutamate Receptor Agonist Activity. J Med Chem. 2002 Jul 18;45(15):3171-83.
  • [2]. H Bräuner-Osborne, et al. Ligands for Glutamate Receptors: Design and Therapeutic Prospects. J Med Chem. 2000 Jul 13;43(14):2609-45.

安全信息

GHS Symbol
Precautionary statements
  • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
Hazard statements
  • H332 Harmful if inhaled 吸入有害
  • H302 Harmful if swallowed 吞食有害
  • H312 Harmful in contact with skin 皮肤接触有害
WGK Germany3
Signal word Warning
Personal Protective Equipment dust mask type N95 (US), Eyeshields, Gloves
Safety Statements
  • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后，立即用大量水冲洗并征求医生意见；
  • S36 Wear suitable protective clothing 穿戴适当的防护服；
Risk Statements
  • R20/21/22 Harmful by inhalation, in contact with skin and if swallowed 吸入、皮肤接触和不慎吞咽有害
Hazard Codes Xn

系列性分类

  1. Life Science 生命科学
  2. Cell Biology 细胞生物学
  3. Bioactive Small Molecules - Cell Biology
  4. Q - Bioactive Small Molecules
  1. Life Science 生命科学
  2. Biochemicals and Reagents 生化试剂
  3. Amino Acids 氨基酸
  4. Modified Amino Acids - Amino Acids
  5. I - Z - Modified Amino Acids
  1. Life Science 生命科学
  2. Cell Biology 细胞生物学
  3. Cell Signaling and Neuroscience - Cell Biology
  4. Ion Channels - Cell Signaling and Neuroscience
  5. Ligand-Gated Ion Channels - Ion Channels
  6. Ionotropic Glutamate Receptor Modulators - Ligand-Gated Ion Channels
  1. Medical Research Areas
  2. GPCR & G Protein
  3. mGluR  (代谢型谷氨酸受体)

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