Meglumine Amidotrizoate 氨基三丙酸甲葡胺

CAS 131-49-7 MFCD00069632

化学结构图

131-49-7
SMILES: CC(=O)Nc1c(I)c(NC(C)=O)c(I)c(C(=O)O)c1I.CNC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO

化学属性

Mol. FormulaC18H26I3N3O9
Mol. Weight614

别名和识别编码

Chemical NameMeglumine Amidotrizoate
MDL NumberMFCD00069632
CAS Number131-49-7
Synonym Amidotrizoate meglumine Angiografin Benzoic acid, 3,5-diacetamido-2,4,6-triiodo-, compd. with Meglumine diatrizoate N-Methyl-D-glucamine diatrizoate
PubChem Substance ID8566
EC Number205-024-7
Chemical Name Translation氨基三丙酸甲葡胺
Wiswesser Line Notation1VMR BI DI FI CVQ EMV1 &Q1YQYQYQYQ1M1
InChIInChI=1S/C11H9I3N2O4.C7H17NO5/c1-3(17)15-9-6(12)5(11(19)20)7(13)10(8(9)14)16-4(2)18;1-8-2-4(10)6(12)7(13)5(11)3-9/h1-2H3,(H,15,17)(H,16,18)(H,19,20);4-13H,2-3H2,1H3/t;4-,5+,6+,7+/m.0/s1
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分类

  • {SNA} Density Gradient Media, Hematology and Histology, Histopaque and Nonionic Iodinated Density Gradient Media, Other Nonionic Iodinated
  • {SNA} Cell Biology, Density Gradient Media, Hematology and Histology, Histopaque and Nonionic Iodinated Density Gradient Media, Other Nonionic Iodinated
  • {SNA} Density Gradient Media, Hematology and Histology, Histopaque and Nonionic Iodinated Density Gradient Media, Other Nonionic Iodinated, 细胞生物学
  • {SNA} Density Gradient Media, Nonionic Iodinated Density Gradient Media, 细胞生物学, 血液学和组织学
  • {SNA} Density Gradient Media, Histopaque and Nonionic Iodinated Density Gradient Media, Other Nonionic Iodinated, 细胞生物学, 血液学和组织学

安全信息

WGK Germany3
RTECSLZ4315000
Personal Protective Equipment Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Unreported
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 19500 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   YAKUD5 Gekkan Yakuji.  Pharmaceuticals Monthly.  (Yakugyo Jihosha, Inaoka
   Bldg., 2-36 Jinbo-cho, Kanda, Chiyoda-ku, Tokyo 101, Japan)  V.1-   1959-
   Volume(issue)/page/year: 26,921,1984

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 14565 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   AAJRDX AJR, American Journal of Roentgenology.  (Williams & Wilkins Co., 428
   E. Preston St., Baltimore, MD 21202)  V.126-    1976-
   Volume(issue)/page/year: 142,619,1984

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Human - man
DOSE/DURATION           : 214 mg/kg
TOXIC EFFECTS :
   Kidney, Ureter, Bladder - changes in both tubules and glomeruli
   Kidney, Ureter, Bladder - interstitial nephritis
   Kidney, Ureter, Bladder - urine volume decreased
REFERENCE :
   34ZIAG "Toxicology of Drugs and Chemicals," Deichmann, W.B., New York,
   Academic Press, Inc., 1969  Volume(issue)/page/year: -,392,1969

TYPE OF

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Parenteral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 44504 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   AAJRDX AJR, American Journal of Roentgenology.  (Williams & Wilkins Co., 428
   E. Preston St., Baltimore, MD 21202)  V.126-    1976-
   Volume(issue)/page/year: 142,619,1984

系列性分类

  1. Life Science 生命科学
  2. Hematology and Histology 血液学和组织学
  3. Density Gradient Media - Hematology and Histology
  4. Histopaque® and Nonionic Iodinated Density Gradient Media - Density Gradient Media
  5. Other Nonionic Iodinated - Histopaque® and Nonionic Iodinated Density Gradient Media

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